Page last updated: 2024-10-18

kynurenine and Pneumonia

kynurenine has been researched along with Pneumonia in 13 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Pneumonia: Infection of the lung often accompanied by inflammation.

Research Excerpts

ExcerptRelevanceReference
"This study analyzed the difference in serum metabolic profiles between patients with severe pneumonia and health individuals through metabolomics, aiming to uncover the correlation between the Tryptophan-Kynurenine pathway and the severity of severe pneumonia, as well as N-3/N-6 polyunsaturated fatty acids (PUFAs)."8.31Correlation between immune-related Tryptophan-Kynurenine pathway and severity of severe pneumonia and inflammation-related polyunsaturated fatty acids. ( Gan, H; Guo, B; Liao, Y; Lin, R; Liu, M; Lyu, J; Sun, B; Xue, M; Zhang, T; Zheng, P, 2023)
"Activation of the kynurenine pathway is associated with the severity and fatal outcomes of AIDS patients with pneumocystis pneumonia."7.91Activation of the kynurenine pathway is associated with poor outcome in Pneumocystis pneumonia patients infected with HIV: results of 2 months cohort study. ( Dai, X; Dong, X; Guo, Y; Hu, C; Huang, Y; Su, J; Wang, M; Zhou, Q; Zhu, B, 2019)
"The kynurenine blood level was found to correlate with seizures."5.27[Elevated kynurenine concentration in the blood serum of children with epilepsy and bronchial asthma]. ( Buzdin, VV; Ivanova, NA; Nikitina, ZS; Ryzhov, IV, 1988)
"This study analyzed the difference in serum metabolic profiles between patients with severe pneumonia and health individuals through metabolomics, aiming to uncover the correlation between the Tryptophan-Kynurenine pathway and the severity of severe pneumonia, as well as N-3/N-6 polyunsaturated fatty acids (PUFAs)."4.31Correlation between immune-related Tryptophan-Kynurenine pathway and severity of severe pneumonia and inflammation-related polyunsaturated fatty acids. ( Gan, H; Guo, B; Liao, Y; Lin, R; Liu, M; Lyu, J; Sun, B; Xue, M; Zhang, T; Zheng, P, 2023)
"In all influenza patients, neopterin concentrations were increased and significantly higher compared to those determined in patients with pneumonia and healthy controls."3.91Assessment of neopterin and indoleamine 2,3-dioxygenase activity in patients with seasonal influenza: A pilot study. ( Bellmann-Weiler, R; Fuchs, D; Kurz, K; Pizzini, A; Santifaller, J; Theurl, I; Tschurtschenthaler, C; Weiss, G, 2019)
"Activation of the kynurenine pathway is associated with the severity and fatal outcomes of AIDS patients with pneumocystis pneumonia."3.91Activation of the kynurenine pathway is associated with poor outcome in Pneumocystis pneumonia patients infected with HIV: results of 2 months cohort study. ( Dai, X; Dong, X; Guo, Y; Hu, C; Huang, Y; Su, J; Wang, M; Zhou, Q; Zhu, B, 2019)
"In this study, the effects of lung inflammation, induced by the intravenous injection of complete Freund's adjuvant, and dietary Trp content on Trp metabolism and availability were investigated."1.35Dietary tryptophan helps to preserve tryptophan homeostasis in pigs suffering from lung inflammation. ( Le Floc'h, N; Melchior, D; Sève, B, 2008)
"The kynurenine blood level was found to correlate with seizures."1.27[Elevated kynurenine concentration in the blood serum of children with epilepsy and bronchial asthma]. ( Buzdin, VV; Ivanova, NA; Nikitina, ZS; Ryzhov, IV, 1988)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19903 (23.08)18.7374
1990's0 (0.00)18.2507
2000's2 (15.38)29.6817
2010's6 (46.15)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Arshad, H1
Siokis, A1
Franke, R1
Habib, A1
Alfonso, JCL1
Poliakova, Y1
Lücke, E1
Michaelis, K1
Brönstrup, M1
Meyer-Hermann, M1
Bilitewski, U1
Vila, J1
Abel, L1
Illig, T1
Schreiber, J1
Pessler, F1
Guo, B1
Xue, M1
Zhang, T1
Gan, H1
Lin, R1
Liu, M1
Liao, Y1
Lyu, J1
Zheng, P1
Sun, B1
Pizzini, A1
Kurz, K1
Santifaller, J1
Tschurtschenthaler, C1
Theurl, I1
Fuchs, D1
Weiss, G1
Bellmann-Weiler, R1
Lee, SM1
Park, HY1
Suh, YS1
Yoon, EH1
Kim, J1
Jang, WH1
Lee, WS1
Park, SG1
Choi, IW1
Choi, I1
Kang, SW1
Yun, H1
Teshima, T1
Kwon, B1
Seo, SK1
Wang, M1
Dong, X1
Huang, Y1
Su, J1
Dai, X1
Guo, Y1
Hu, C1
Zhou, Q1
Zhu, B1
Meier, MA1
Ottiger, M1
Vögeli, A1
Steuer, C1
Bernasconi, L1
Thomann, R1
Christ-Crain, M1
Henzen, C1
Hoess, C1
Zimmerli, W1
Huber, A1
Mueller, B1
Schuetz, P1
Le Floc'h, N2
Melchior, D2
Sève, B2
de Luca, A1
Bozza, S1
Zelante, T1
Zagarella, S1
D'Angelo, C1
Perruccio, K1
Vacca, C1
Carvalho, A1
Cunha, C1
Aversa, F1
Romani, L1
Suzuki, Y1
Suda, T1
Yokomura, K1
Suzuki, M1
Fujie, M1
Furuhashi, K1
Hahimoto, D1
Enomto, N1
Fujisawa, T1
Nakamura, Y1
Inui, N1
Nakano, Y1
Nakamura, H1
Chida, K1
Ivanova, NA1
Ryzhov, IV1
Buzdin, VV1
Nikitina, ZS1
Kontsevaia, NG2
Shapiro, SE1
Kureeva, RIa1
Koval'skiĭ, GS1
Kondrat'ev, VG2

Other Studies

13 other studies available for kynurenine and Pneumonia

ArticleYear
Reprogramming of Amino Acid Metabolism Differs between Community-Acquired Pneumonia and Infection-Associated Exacerbation of Chronic Obstructive Pulmonary Disease.
    Cells, 2022, 07-24, Volume: 11, Issue:15

    Topics: Asparagine; Biomarkers; Community-Acquired Infections; Convalescence; Humans; Kynurenine; Pneumonia;

2022
Correlation between immune-related Tryptophan-Kynurenine pathway and severity of severe pneumonia and inflammation-related polyunsaturated fatty acids.
    Immunity, inflammation and disease, 2023, Volume: 11, Issue:11

    Topics: Arachidonic Acid; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Humans; Hydroxyeicosatetraenoic Ac

2023
Assessment of neopterin and indoleamine 2,3-dioxygenase activity in patients with seasonal influenza: A pilot study.
    Influenza and other respiratory viruses, 2019, Volume: 13, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Female; Hospitalization; Humans; Indoleamine-Pyrrole 2,3

2019
Inhibition of acute lethal pulmonary inflammation by the IDO-AhR pathway.
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 07-18, Volume: 114, Issue:29

    Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Female; Graft vs Host Disease; Hematopoietic

2017
Activation of the kynurenine pathway is associated with poor outcome in Pneumocystis pneumonia patients infected with HIV: results of 2 months cohort study.
    BMC infectious diseases, 2019, Mar-04, Volume: 19, Issue:1

    Topics: Adult; Antifungal Agents; Area Under Curve; Biomarkers; Chromatography, High Pressure Liquid; Cohort

2019
Activation of the tryptophan/serotonin pathway is associated with severity and predicts outcomes in pneumonia: results of a long-term cohort study.
    Clinical chemistry and laboratory medicine, 2017, Jun-27, Volume: 55, Issue:7

    Topics: Aged; Aged, 80 and over; Biomarkers; Cohort Studies; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxyg

2017
Dietary tryptophan helps to preserve tryptophan homeostasis in pigs suffering from lung inflammation.
    Journal of animal science, 2008, Volume: 86, Issue:12

    Topics: Animals; Antioxidants; Diet; Dietary Supplements; Female; Haptoglobins; Homeostasis; Kynurenine; Mal

2008
Non-hematopoietic cells contribute to protective tolerance to Aspergillus fumigatus via a TRIF pathway converging on IDO.
    Cellular & molecular immunology, 2010, Volume: 7, Issue:6

    Topics: Adaptor Proteins, Vesicular Transport; Animals; Aspergillus fumigatus; Disease Susceptibility; Down-

2010
Serum activity of indoleamine 2,3-dioxygenase predicts prognosis of community-acquired pneumonia.
    The Journal of infection, 2011, Volume: 63, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Community-Acquired Infections; Female; Humans; Indoleami

2011
Effects of chronic lung inflammation on tryptophan metabolism in piglets.
    Advances in experimental medicine and biology, 2003, Volume: 527

    Topics: Animals; Chronic Disease; Freund's Adjuvant; Kynurenine; Pneumonia; Sus scrofa; Swine Diseases; Tryp

2003
[Elevated kynurenine concentration in the blood serum of children with epilepsy and bronchial asthma].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1988, Volume: 88, Issue:6

    Topics: Adolescent; Asthma; Child; Child, Preschool; Chronic Disease; Epilepsy; Female; Humans; Kynurenine;

1988
[Aromatic compounds in certain infectious diseases].
    Klinicheskaia meditsina, 1973, Volume: 51, Issue:5

    Topics: Amino Acids; Erysipelas; Homogentisic Acid; Humans; Indican; Infections; Kynurenine; Liver Diseases;

1973
[Balance and metabolism of tryptophan in pneumonia].
    Terapevticheskii arkhiv, 1971, Volume: 43, Issue:5

    Topics: Adult; Chronic Disease; Focal Infection; Humans; Kynurenine; Male; Pneumonia; Spectrophotometry; Try

1971