kynurenine has been researched along with Pain, Chronic in 3 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pro-inflammatory cytokines from persistent low-grade inflammation not only contribute to the development of chronic pain conditions, but also regulate various aspects of the tryptophan metabolism, especially that of the kynurenine pathway (KP)." | 9.41 | Glucocorticoid Hormones as Modulators of the Kynurenine Pathway in Chronic Pain Conditions. ( Jovanovic, F; Jovanovic, V; Knezevic, NN, 2023) |
| "Since chronic painful conditions and depression have common pathophysiological patterns, and the kynurenine signaling pathway is involved in both of them, future clinical studies should aim to have outcomes targeting not only pain, but also functionality, mood changes, and quality of life." | 6.66 | The Role of the Kynurenine Signaling Pathway in Different Chronic Pain Conditions and Potential Use of Therapeutic Agents. ( Candido, KD; Jovanovic, F; Knezevic, NN, 2020) |
| " Pro-inflammatory cytokines from persistent low-grade inflammation not only contribute to the development of chronic pain conditions, but also regulate various aspects of the tryptophan metabolism, especially that of the kynurenine pathway (KP)." | 5.41 | Glucocorticoid Hormones as Modulators of the Kynurenine Pathway in Chronic Pain Conditions. ( Jovanovic, F; Jovanovic, V; Knezevic, NN, 2023) |
| "Since chronic painful conditions and depression have common pathophysiological patterns, and the kynurenine signaling pathway is involved in both of them, future clinical studies should aim to have outcomes targeting not only pain, but also functionality, mood changes, and quality of life." | 2.66 | The Role of the Kynurenine Signaling Pathway in Different Chronic Pain Conditions and Potential Use of Therapeutic Agents. ( Candido, KD; Jovanovic, F; Knezevic, NN, 2020) |
| "Chronic pain was evaluated by thermal hyperalgesia in Hargreaves test and mechanical allodynia in von Frey test, depressive-like behaviors were evaluated by immobility time in forced swim test and tail suspension test." | 1.48 | Chronic trans-astaxanthin treatment exerts antihyperalgesic effect and corrects co-morbid depressive like behaviors in mice with chronic pain. ( Ding, L; Jiang, X; Jing, C; Liu, F; Pang, C; Yan, Q; Zhang, L, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Jovanovic, F | 2 |
| Jovanovic, V | 1 |
| Knezevic, NN | 2 |
| Candido, KD | 1 |
| Jiang, X | 1 |
| Yan, Q | 1 |
| Liu, F | 1 |
| Jing, C | 1 |
| Ding, L | 1 |
| Zhang, L | 1 |
| Pang, C | 1 |
2 reviews available for kynurenine and Pain, Chronic
| Article | Year |
|---|---|
Glucocorticoid Hormones as Modulators of the Kynurenine Pathway in Chronic Pain Conditions.
Topics: Chronic Pain; Cytokines; Glucocorticoids; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; In | 2023 |
The Role of the Kynurenine Signaling Pathway in Different Chronic Pain Conditions and Potential Use of Therapeutic Agents.
Topics: Analgesics; Animals; Chronic Pain; Depression; Headache; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenas | 2020 |
1 other study available for kynurenine and Pain, Chronic
| Article | Year |
|---|---|
Chronic trans-astaxanthin treatment exerts antihyperalgesic effect and corrects co-morbid depressive like behaviors in mice with chronic pain.
Topics: Analgesics; Animals; Behavior, Animal; Chronic Pain; Cytokines; Depression; Hydroxyindoleacetic Acid | 2018 |