kynurenine has been researched along with Multiple Sclerosis, Chronic Progressive in 2 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
Multiple Sclerosis, Chronic Progressive: A form of multiple sclerosis characterized by a progressive deterioration in neurologic function which is in contrast to the more typical relapsing remitting form. If the clinical course is free of distinct remissions, it is referred to as primary progressive multiple sclerosis. When the progressive decline is punctuated by acute exacerbations, it is referred to as progressive relapsing multiple sclerosis. The term secondary progressive multiple sclerosis is used when relapsing remitting multiple sclerosis evolves into the chronic progressive form. (From Ann Neurol 1994;36 Suppl:S73-S79; Adams et al., Principles of Neurology, 6th ed, pp903-914)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bansi, J | 1 |
| Koliamitra, C | 1 |
| Bloch, W | 1 |
| Joisten, N | 1 |
| Schenk, A | 1 |
| Watson, M | 1 |
| Kool, J | 1 |
| Langdon, D | 1 |
| Dalgas, U | 1 |
| Kesselring, J | 1 |
| Zimmer, P | 1 |
| Herman, S | 1 |
| Åkerfeldt, T | 1 |
| Spjuth, O | 1 |
| Burman, J | 1 |
| Kultima, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Transient and Immediate Motor Effects of Exercise in Progressive Multiple Sclerosis: A Pilot Study.[NCT05562414] | 30 participants (Anticipated) | Interventional | 2022-10-01 | Recruiting | |||
| The Influence of High-Intensity Interval Training Compared to Moderate Continuous Training on Cardiorespiratory Fitness, Symptom Improvement, and Disease-specific Biomarkers in Primary Progressive Multiple Sclerosis[NCT05229861] | 61 participants (Anticipated) | Interventional | 2022-05-10 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for kynurenine and Multiple Sclerosis, Chronic Progressive
1 other study available for kynurenine and Multiple Sclerosis, Chronic Progressive
| Article | Year |
|---|---|
Biochemical Differences in Cerebrospinal Fluid between Secondary Progressive and Relapsing⁻Remitting Multiple Sclerosis.
Topics: Adult; Case-Control Studies; Female; Humans; Kynurenine; Male; Metabolome; Middle Aged; Multiple Scl | 2019 |