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kynurenine and Mitochondrial Diseases

kynurenine has been researched along with Mitochondrial Diseases in 5 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Mitochondrial Diseases: Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.

Research Excerpts

ExcerptRelevanceReference
" The second part of the review deals with the kynurenine metabolic pathway, its alterations and their potential association with cellular energy impairment in certain neurodegenerative diseases."4.84Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders. ( Robotka, H; Sas, K; Toldi, J; Vécsei, L, 2007)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Tanaka, M1
Szabó, Á1
Spekker, E1
Polyák, H1
Tóth, F1
Vécsei, L2
Castellano-Gonzalez, G1
Jacobs, KR1
Don, E1
Cole, NJ1
Adams, S1
Lim, CK1
Lovejoy, DB1
Guillemin, GJ1
Ward, JM1
Stoyas, CA1
Switonski, PM1
Ichou, F1
Fan, W1
Collins, B1
Wall, CE1
Adanyeguh, I1
Niu, C1
Sopher, BL1
Kinoshita, C1
Morrison, RS1
Durr, A1
Muotri, AR1
Evans, RM1
Mochel, F1
La Spada, AR1
Reyes-Ocampo, J1
Ramírez-Ortega, D1
Cervantes, GI1
Pineda, B1
Balderas, PM1
González-Esquivel, D1
Sánchez-Chapul, L1
Lugo-Huitrón, R1
Silva-Adaya, D1
Ríos, C1
Jiménez-Anguiano, A1
Pérez-de la Cruz, V1
Sas, K1
Robotka, H1
Toldi, J1

Reviews

2 reviews available for kynurenine and Mitochondrial Diseases

ArticleYear
Mitochondrial Impairment: A Common Motif in Neuropsychiatric Presentation? The Link to the Tryptophan-Kynurenine Metabolic System.
    Cells, 2022, 08-21, Volume: 11, Issue:16

    Topics: Animals; DNA, Mitochondrial; Humans; Kynurenine; Mitochondria; Mitochondrial Diseases; Tryptophan

2022
Mitochondria, metabolic disturbances, oxidative stress and the kynurenine system, with focus on neurodegenerative disorders.
    Journal of the neurological sciences, 2007, Jun-15, Volume: 257, Issue:1-2

    Topics: Animals; Brain; Brain Diseases, Metabolic; Energy Metabolism; Humans; Kynurenine; Mitochondria; Mito

2007

Other Studies

3 other studies available for kynurenine and Mitochondrial Diseases

ArticleYear
Kynurenine 3-Monooxygenase Activity in Human Primary Neurons and Effect on Cellular Bioenergetics Identifies New Neurotoxic Mechanisms.
    Neurotoxicity research, 2019, Volume: 35, Issue:3

    Topics: Adenosine Triphosphate; Brain; Cell Survival; HEK293 Cells; Humans; Kynurenic Acid; Kynurenine; Kynu

2019
Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease.
    Cell reports, 2019, 01-29, Volume: 26, Issue:5

    Topics: Adipose Tissue; Animals; Ataxin-7; Blood Glucose; Energy Metabolism; Humans; Kynurenine; Metabolomic

2019
Mitochondrial dysfunction related to cell damage induced by 3-hydroxykynurenine and 3-hydroxyanthranilic acid: Non-dependent-effect of early reactive oxygen species production.
    Neurotoxicology, 2015, Volume: 50

    Topics: 3-Hydroxyanthranilic Acid; Animals; Astrocytes; Brain; Cells, Cultured; Cerebral Cortex; Disease Mod

2015