kynurenine and Mesothelioma studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Mesothelioma: A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed)

Research Excerpts

Excerpt	Relevance	Reference
"Kynurenine synthesis was due to the transcription of the indoleamine 1,2 dioxygenase (IDO) enzyme, consequent to the activation of the signal transducer and activator of transcription-3 (STAT3)."	5.42	Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma. ( Campia, I; Gazzano, E; Ghigo, D; Kopecka, J; Orecchia, S; Riganti, C; Salaroglio, IC, 2015)
"Kynurenine synthesis was due to the transcription of the indoleamine 1,2 dioxygenase (IDO) enzyme, consequent to the activation of the signal transducer and activator of transcription-3 (STAT3)."	1.42	Zoledronic acid overcomes chemoresistance and immunosuppression of malignant mesothelioma. ( Campia, I; Gazzano, E; Ghigo, D; Kopecka, J; Orecchia, S; Riganti, C; Salaroglio, IC, 2015)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

kynurenine and Mesothelioma

Research Excerpts

Research

Studies (1)

Authors

Other Studies

Authors	Studies
Salaroglio, IC	1
Campia, I	1
Kopecka, J	1
Gazzano, E	1
Orecchia, S	1
Ghigo, D	1
Riganti, C	1