kynurenine has been researched along with Meningitis, Bacterial in 2 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
Meningitis, Bacterial: Bacterial infections of the leptomeninges and subarachnoid space, frequently involving the cerebral cortex, cranial nerves, cerebral blood vessels, spinal cord, and nerve roots.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Activation of the kynurenine (KYN) pathway (KP) has been reported in various neurological diseases as a consequence of inflammation." | 3.80 | The kynurenine pathway is involved in bacterial meningitis. ( Agnez-Lima, LF; Bellac, CL; Christen, S; Coutinho, LG; Fontes, FL; Grandgirard, D; Leib, SL; Souza, FR, 2014) |
| "Acute bacterial meningitis (ABM) causes excessive activation of N-methyl-D-aspartate receptors (NMDAr), leading to cortical and hippocampal neuron death." | 1.91 | The neurotoxic branch of the kynurenine pathway is highly activated in the central nervous system of patients with pneumococcal meningitis. ( Campi-Azevedo, AC; Candiani, TMS; Cassiano, LMG; Coimbra, RS; de Oliveira, DB; Kohlhoff, M; Kroon, EG; Martins-Filho, OA, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cassiano, LMG | 1 |
| de Oliveira, DB | 1 |
| Candiani, TMS | 1 |
| Campi-Azevedo, AC | 1 |
| Martins-Filho, OA | 1 |
| Kroon, EG | 1 |
| Kohlhoff, M | 1 |
| Coimbra, RS | 1 |
| Coutinho, LG | 1 |
| Christen, S | 1 |
| Bellac, CL | 1 |
| Fontes, FL | 1 |
| Souza, FR | 1 |
| Grandgirard, D | 1 |
| Leib, SL | 1 |
| Agnez-Lima, LF | 1 |
2 other studies available for kynurenine and Meningitis, Bacterial
| Article | Year |
|---|---|
The neurotoxic branch of the kynurenine pathway is highly activated in the central nervous system of patients with pneumococcal meningitis.
Topics: Central Nervous System; Child; Humans; Interleukin-10; Interleukin-6; Kynurenine; Meningitis, Bacter | 2023 |
The kynurenine pathway is involved in bacterial meningitis.
Topics: Adolescent; Adult; Chromatography, High Pressure Liquid; Cytokines; Female; Humans; Inflammation; Ky | 2014 |