Page last updated: 2024-10-18

kynurenine and Malaria

kynurenine has been researched along with Malaria in 6 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Research Excerpts

ExcerptRelevanceReference
"Other than Kaposi sarcoma (KS)-associated herpesvirus and CD4 T-cell lymphopenia, the mechanisms responsible for KS in the context of HIV are poorly understood."5.42The Kynurenine Pathway of Tryptophan Catabolism and AIDS-Associated Kaposi Sarcoma in Africa. ( Bangsberg, DR; Bennett, J; Bwana, BM; Byakwaga, H; Dollard, SC; Glidden, DV; Huang, Y; Hunt, PW; Laker-Oketta, M; Martin, JN; Mbidde, EK; Mocello, AR; Walusansa, V, 2015)
"In Anopheles gambiae, the most efficient vector of the malaria parasite Plasmodium falciparum, 3-hydroxykynurenine is endowed with a toxic potential."3.91Study of Anopheles gambiae 3-hydroxykynurenine transaminase activity and inhibition by LC-MS/MS method. ( Canavesi, R; Del Grosso, E; Galli, U; Miggiano, R; Rizzi, M; Rossi, F; Stella, M, 2019)
"Other than Kaposi sarcoma (KS)-associated herpesvirus and CD4 T-cell lymphopenia, the mechanisms responsible for KS in the context of HIV are poorly understood."1.42The Kynurenine Pathway of Tryptophan Catabolism and AIDS-Associated Kaposi Sarcoma in Africa. ( Bangsberg, DR; Bennett, J; Bwana, BM; Byakwaga, H; Dollard, SC; Glidden, DV; Huang, Y; Hunt, PW; Laker-Oketta, M; Martin, JN; Mbidde, EK; Mocello, AR; Walusansa, V, 2015)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Canavesi, R1
Miggiano, R1
Stella, M1
Galli, U1
Rossi, F1
Rizzi, M1
Del Grosso, E1
Byakwaga, H1
Hunt, PW1
Laker-Oketta, M1
Glidden, DV1
Huang, Y1
Bwana, BM1
Mocello, AR1
Bennett, J1
Walusansa, V1
Dollard, SC1
Bangsberg, DR1
Mbidde, EK1
Martin, JN1
Jortzik, E1
Zocher, K1
Isernhagen, A1
Mailu, BM1
Rahlfs, S1
Viola, G1
Wittlin, S1
Hunt, NH3
Ihmels, H1
Becker, K1
Wang, Y1
Liu, H1
McKenzie, G1
Witting, PK1
Stasch, JP1
Hahn, M1
Changsirivathanathamrong, D1
Wu, BJ1
Ball, HJ1
Thomas, SR2
Kapoor, V1
Celermajer, DS1
Mellor, AL1
Keaney, JF1
Stocker, R2
Tetsutani, K1
To, H1
Torii, M1
Hisaeda, H1
Himeno, K1
Sanni, LA1
Tattam, BN1
Moore, DE1
Chaudhri, G1

Other Studies

6 other studies available for kynurenine and Malaria

ArticleYear
Study of Anopheles gambiae 3-hydroxykynurenine transaminase activity and inhibition by LC-MS/MS method.
    Journal of pharmaceutical and biomedical analysis, 2019, Sep-05, Volume: 173

    Topics: Animals; Anopheles; Enzyme Assays; Enzyme Inhibitors; Insecticides; Kynurenine; Malaria; Mosquito Ve

2019
The Kynurenine Pathway of Tryptophan Catabolism and AIDS-Associated Kaposi Sarcoma in Africa.
    Journal of acquired immune deficiency syndromes (1999), 2015, Nov-01, Volume: 70, Issue:3

    Topics: Adult; AIDS-Related Opportunistic Infections; Female; Gene Expression Regulation, Enzymologic; Human

2015
Benzo[b]quinolizinium Derivatives Have a Strong Antimalarial Activity and Inhibit Indoleamine Dioxygenase.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:1

    Topics: Animals; Antimalarials; Cell Line, Tumor; Cell Survival; Cloning, Molecular; Crystallography, X-Ray;

2016
Kynurenine is an endothelium-derived relaxing factor produced during inflammation.
    Nature medicine, 2010, Volume: 16, Issue:3

    Topics: Adenylyl Cyclases; Animals; Blood Pressure; Coronary Vessels; Dose-Response Relationship, Drug; Endo

2010
Malaria parasite induces tryptophan-related immune suppression in mice.
    Parasitology, 2007, Volume: 134, Issue:Pt 7

    Topics: Animals; Antimalarials; CD4-Positive T-Lymphocytes; Chloroquine; Enzyme Activation; Enzyme Inhibitor

2007
Dramatic changes in oxidative tryptophan metabolism along the kynurenine pathway in experimental cerebral and noncerebral malaria.
    The American journal of pathology, 1998, Volume: 152, Issue:2

    Topics: Animals; Aspartic Acid; Brain; Brain Diseases; Female; Glutamic Acid; Indoleamine-Pyrrole 2,3,-Dioxy

1998