kynurenine has been researched along with Lymph Node Metastasis in 8 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Esophageal squamous cell carcinoma (ESCC) is one of the most frequent malignancies worldwide." | 5.46 | Disturbed tryptophan metabolism correlating to progression and metastasis of esophageal squamous cell carcinoma. ( Cheng, J; Gao, X; Hou, X; Jin, H; Lv, J; Zheng, G, 2017) |
| "17 patients with pancreatic adenocarcinoma were recruited and completed mood questionnaires (Functional Assessment of Cancer Therapy -Pancreatic Cancer, Beck Depression Inventory and the Beck Anxiety Inventory) and blood testing for serum levels of tryptophan, kynurenine, kynurenic acid and quinolinic acid." | 3.80 | A biological basis for depression in pancreatic cancer. ( Botwinick, IC; Chabot, JA; Cooper, T; Mann, JJ; Pursell, L; Yu, G, 2014) |
| "Esophageal squamous cell carcinoma (ESCC) is one of the most frequent malignancies worldwide." | 1.46 | Disturbed tryptophan metabolism correlating to progression and metastasis of esophageal squamous cell carcinoma. ( Cheng, J; Gao, X; Hou, X; Jin, H; Lv, J; Zheng, G, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, QH | 1 |
| Han, H | 1 |
| Lu, JB | 1 |
| Liu, TY | 1 |
| Huang, KB | 1 |
| Deng, CZ | 1 |
| Li, ZS | 1 |
| Chen, JP | 1 |
| Yao, K | 1 |
| Qin, ZK | 1 |
| Liu, ZW | 1 |
| Li, YH | 1 |
| Guo, SJ | 1 |
| Ye, YL | 1 |
| Zhou, FJ | 1 |
| Liu, RY | 1 |
| Masaki, A | 1 |
| Ishida, T | 1 |
| Maeda, Y | 1 |
| Ito, A | 1 |
| Suzuki, S | 1 |
| Narita, T | 1 |
| Kinoshita, S | 1 |
| Yoshida, T | 1 |
| Ri, M | 1 |
| Kusumoto, S | 1 |
| Komatsu, H | 1 |
| Inagaki, H | 1 |
| Ueda, R | 1 |
| Choi, I | 1 |
| Suehiro, Y | 1 |
| Iida, S | 1 |
| Cheng, J | 1 |
| Jin, H | 1 |
| Hou, X | 1 |
| Lv, J | 1 |
| Gao, X | 1 |
| Zheng, G | 1 |
| Xiang, Z | 1 |
| Li, J | 1 |
| Song, S | 1 |
| Wang, J | 1 |
| Cai, W | 1 |
| Hu, W | 1 |
| Ji, J | 1 |
| Zhu, Z | 1 |
| Zang, L | 1 |
| Yan, R | 1 |
| Yu, Y | 1 |
| Iversen, TZ | 1 |
| Engell-Noerregaard, L | 1 |
| Ellebaek, E | 1 |
| Andersen, R | 1 |
| Larsen, SK | 1 |
| Bjoern, J | 1 |
| Zeyher, C | 1 |
| Gouttefangeas, C | 1 |
| Thomsen, BM | 1 |
| Holm, B | 1 |
| Thor Straten, P | 1 |
| Mellemgaard, A | 1 |
| Andersen, MH | 1 |
| Svane, IM | 1 |
| Botwinick, IC | 1 |
| Pursell, L | 1 |
| Yu, G | 1 |
| Cooper, T | 1 |
| Mann, JJ | 1 |
| Chabot, JA | 1 |
| Engin, A | 1 |
| Gonul, II | 1 |
| Engin, AB | 1 |
| Karamercan, A | 1 |
| Sepici Dincel, A | 1 |
| Dursun, A | 1 |
| Rose, DP | 1 |
| Randall, ZC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Open-label, Randomized, Phase I/II Trial Investigating the Safety and Efficacy of IO102 in Combination With Pembrolizumab, With or Without Chemotherapy, as First-line Treatment for Patients With Metastatic Non-Small Cell Lung Cancer[NCT03562871] | Phase 1/Phase 2 | 109 participants (Actual) | Interventional | 2018-08-22 | Completed | ||
| IDO Peptid Vaccination in Combination With Immune Stimulating Agent Aldara and the Adjuvant Montanide, for Treatment of Patients With Locally Advanced or Metastatic Non Small-cell Lung Cancer. A First-in-man Phase I Trial.[NCT01219348] | Phase 1 | 14 participants (Actual) | Interventional | 2010-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for kynurenine and Lymph Node Metastasis
| Article | Year |
|---|---|
Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase.
Topics: Adenocarcinoma; Adjuvants, Immunologic; Aged; Cancer Vaccines; Carcinoma, Non-Small-Cell Lung; Disea | 2014 |
Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase.
Topics: Adenocarcinoma; Adjuvants, Immunologic; Aged; Cancer Vaccines; Carcinoma, Non-Small-Cell Lung; Disea | 2014 |
Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase.
Topics: Adenocarcinoma; Adjuvants, Immunologic; Aged; Cancer Vaccines; Carcinoma, Non-Small-Cell Lung; Disea | 2014 |
Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase.
Topics: Adenocarcinoma; Adjuvants, Immunologic; Aged; Cancer Vaccines; Carcinoma, Non-Small-Cell Lung; Disea | 2014 |
7 other studies available for kynurenine and Lymph Node Metastasis
| Article | Year |
|---|---|
Up-regulation of indoleamine 2,3-dioxygenase 1 (IDO1) expression and catalytic activity is associated with immunosuppression and poor prognosis in penile squamous cell carcinoma patients.
Topics: Adult; Aged; Aged, 80 and over; B7-H1 Antigen; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Lin | 2020 |
Clinical significance of tryptophan catabolism in follicular lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Female; Humans; Immunohistochemistry; Kynurenine; | 2020 |
Disturbed tryptophan metabolism correlating to progression and metastasis of esophageal squamous cell carcinoma.
Topics: 5-Hydroxytryptophan; Aged; Biomarkers, Tumor; Carcinoma, Squamous Cell; Case-Control Studies; Diseas | 2017 |
A positive feedback between IDO1 metabolite and COL12A1 via MAPK pathway to promote gastric cancer metastasis.
Topics: Animals; Cell Line, Tumor; Cell Movement; Collagen Type XII; Gene Expression Regulation, Neoplastic; | 2019 |
A biological basis for depression in pancreatic cancer.
Topics: Adenocarcinoma; Affect; Aged; Aged, 80 and over; Depression; Female; Humans; Kynurenine; Lymphatic M | 2014 |
Relationship between indoleamine 2,3-dioxygenase activity and lymphatic invasion propensity of colorectal carcinoma.
Topics: Biomarkers, Tumor; Biopterins; Carcinoma; Case-Control Studies; Chromatography, High Pressure Liquid | 2016 |
Tryptophan metabolism in early and advanced breast cancer and carcinoma of the cervix.
Topics: Administration, Oral; Adult; Aged; Bone Neoplasms; Breast Neoplasms; Carcinoma; Female; Humans; Kynu | 1972 |