kynurenine has been researched along with Liver Failure, Acute in 2 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, the effect of acute liver failure (ALF) on brain KYNA production and on the peripheral tryptophan metabolism was investigated in rats." | 1.51 | Acute liver failure increases kynurenic acid production in rat brain via changes in tryptophan metabolism in the periphery. ( Fukuwatari, T; Sekine, A, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sekine, A | 1 |
| Fukuwatari, T | 1 |
| Hilgier, W | 1 |
| Kocki, T | 1 |
| Obara-Michlewska, M | 1 |
| Turski, WA | 1 |
| Oja, SS | 1 |
| Saransaari, P | 1 |
| Albrecht, J | 1 |
2 other studies available for kynurenine and Liver Failure, Acute
| Article | Year |
|---|---|
Acute liver failure increases kynurenic acid production in rat brain via changes in tryptophan metabolism in the periphery.
Topics: Animals; Kynurenic Acid; Kynurenine; Liver Failure, Acute; Male; Rats; Rats, Wistar; Thioacetamide | 2019 |
Modulation by kynurenine of extracellular kynurenate and glutamate in cerebral cortex of rats with acute liver failure.
Topics: Animals; Cerebral Cortex; Glutamic Acid; Kynurenic Acid; Kynurenine; Liver Failure, Acute; Male; Rat | 2014 |