kynurenine has been researched along with Leukemia, Myeloid, Acute in 8 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
Leukemia, Myeloid, Acute: Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Because blasts from patients with acute myeloid leukemia (AML) express IDO, the goal of this study was to investigate the role of L-kynurenine as a prognostic marker for AML." | 1.43 | High serum concentration of L-kynurenine predicts unfavorable outcomes in patients with acute myeloid leukemia. ( Goto, N; Hara, T; Ito, H; Kanemura, N; Kitagawa, J; Mabuchi, R; Matsumoto, T; Moriwaki, H; Nakamura, H; Nakamura, N; Saito, K; Shibata, Y; Shimizu, M; Tsurumi, H; Yamamoto, Y, 2016) |
| "In patients with acute myeloid leukemia (AML), the serum kynurenine/tryptophan ratio (Kyn/Trp) was raised, suggesting a higher IDO activity than in healthy people." | 1.35 | Indoleamine 2,3-dioxygenase activity of acute myeloid leukemia cells can be measured from patients' sera by HPLC and is inducible by IFN-gamma. ( Berthon, C; Biggio, V; Briche, I; Corm, S; Dupont, C; Imbenotte, M; Lhermitte, M; Quesnel, B, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 4 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Galán-Díez, M | 1 |
| Borot, F | 1 |
| Ali, AM | 1 |
| Zhao, J | 1 |
| Gil-Iturbe, E | 1 |
| Shan, X | 1 |
| Luo, N | 1 |
| Liu, Y | 1 |
| Huang, XP | 1 |
| Bisikirska, B | 1 |
| Labella, R | 1 |
| Kurland, I | 1 |
| Roth, BL | 1 |
| Quick, M | 1 |
| Mukherjee, S | 1 |
| Rabadán, R | 1 |
| Carroll, M | 1 |
| Raza, A | 1 |
| Kousteni, S | 1 |
| Kierdorf, F | 1 |
| Zimmer, P | 1 |
| Joisten, N | 1 |
| Kiesl, D | 1 |
| Winker, M | 1 |
| Rigoux, L | 1 |
| Elter, T | 1 |
| Sobash, PT | 1 |
| Kolhe, R | 1 |
| Karim, NA | 1 |
| Guddati, AK | 1 |
| Jillella, A | 1 |
| Kota, V | 1 |
| Wells, G | 1 |
| Kennedy, PT | 1 |
| Dahal, LN | 1 |
| Iachininoto, MG | 1 |
| Nuzzolo, ER | 1 |
| Bonanno, G | 1 |
| Mariotti, A | 1 |
| Procoli, A | 1 |
| Locatelli, F | 1 |
| De Cristofaro, R | 1 |
| Rutella, S | 1 |
| Mabuchi, R | 1 |
| Hara, T | 2 |
| Matsumoto, T | 2 |
| Shibata, Y | 2 |
| Nakamura, N | 2 |
| Nakamura, H | 2 |
| Kitagawa, J | 2 |
| Kanemura, N | 1 |
| Goto, N | 1 |
| Shimizu, M | 2 |
| Ito, H | 2 |
| Yamamoto, Y | 1 |
| Saito, K | 2 |
| Moriwaki, H | 1 |
| Tsurumi, H | 2 |
| Ninomiya, S | 1 |
| Nannya, Y | 1 |
| Corm, S | 1 |
| Berthon, C | 1 |
| Imbenotte, M | 1 |
| Biggio, V | 1 |
| Lhermitte, M | 1 |
| Dupont, C | 1 |
| Briche, I | 1 |
| Quesnel, B | 1 |
2 reviews available for kynurenine and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Role of indoleamine 2,3-dioxygenase in acute myeloid leukemia.
Topics: Antineoplastic Agents; Cell Differentiation; Dendritic Cells; Disease Progression; Gene Expression R | 2020 |
Investigating the Role of Indoleamine 2,3-Dioxygenase in Acute Myeloid Leukemia: A Systematic Review.
Topics: Antineoplastic Agents; Cell Proliferation; Gene Expression Regulation, Leukemic; Humans; Indoleamine | 2021 |
6 other studies available for kynurenine and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Subversion of Serotonin Receptor Signaling in Osteoblasts by Kynurenine Drives Acute Myeloid Leukemia.
Topics: Animals; Humans; Kynurenine; Leukemia, Myeloid, Acute; Mice; Osteoblasts; Signal Transduction; Tumor | 2022 |
L-kynurenine as a prognostic marker for early mortality in patients with acute myeloid leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Humans; Kynurenine; Leukemia, Myeloid, Acute; Progno | 2022 |
Cyclooxygenase-2 (COX-2) inhibition constrains indoleamine 2,3-dioxygenase 1 (IDO1) activity in acute myeloid leukaemia cells.
Topics: Coculture Techniques; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Enzyme Induction; | 2013 |
High serum concentration of L-kynurenine predicts unfavorable outcomes in patients with acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Chromosome Banding; Female; Humans; I | 2016 |
Prognostic value of the combination of serum l-kynurenine level and indoleamine 2,3-dioxygenase mRNA expression in acute myeloid leukemia.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Female; Gene Expression Regulation, Enzymologic; | 2016 |
Indoleamine 2,3-dioxygenase activity of acute myeloid leukemia cells can be measured from patients' sera by HPLC and is inducible by IFN-gamma.
Topics: Blast Crisis; Chromatography, High Pressure Liquid; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; In | 2009 |