kynurenine has been researched along with Insulin Sensitivity in 12 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study examined the diagnostic ability of tryptophan catabolites (TRYCATs) and insulin resistance (IR) parameters in women with PE." | 8.31 | Maternal Tryptophan Catabolites and Insulin Resistance Parameters in Preeclampsia. ( Al-Hakeim, HK; Jasim, ZA; Stanek, A; Zolghadri, S, 2023) |
| "An extensive body of literature indicates a relationship between insulin resistance and the up-regulation of the kynurenine pathway, i." | 7.85 | Successful metformin treatment of insulin resistance is associated with down-regulation of the kynurenine pathway. ( Burghardt, P; Kumar, A; Muzik, O; Seyoum, B; Yi, Z, 2017) |
| " The present study examined the diagnostic ability of tryptophan catabolites (TRYCATs) and insulin resistance (IR) parameters in women with PE." | 4.31 | Maternal Tryptophan Catabolites and Insulin Resistance Parameters in Preeclampsia. ( Al-Hakeim, HK; Jasim, ZA; Stanek, A; Zolghadri, S, 2023) |
| "GM changes accompanying pregnancy shift IDO1-dependent tryptophan metabolism toward kynurenine production, intestinal inflammation, and gestational IR, a phenotype reversed by genetic deletion or inhibition of IDO1." | 4.12 | Gestational Insulin Resistance Is Mediated by the Gut Microbiome-Indoleamine 2,3-Dioxygenase Axis. ( Allard, S; Bernabe, BP; Chlipala, GE; Dai, Y; Garcia, MS; Gilbert, J; Gill, RK; Khan, MW; Layden, BT; Lednovich, K; Maki, PM; Manzella, CR; Navarro, G; Perdew, GH; Priyadarshini, M; Reiman, DJ; Sharma, A; Szynal, B; Wicksteed, B; Xu, K, 2022) |
| "An extensive body of literature indicates a relationship between insulin resistance and the up-regulation of the kynurenine pathway, i." | 3.85 | Successful metformin treatment of insulin resistance is associated with down-regulation of the kynurenine pathway. ( Burghardt, P; Kumar, A; Muzik, O; Seyoum, B; Yi, Z, 2017) |
| " Obese women had significantly higher circulating BCAA and kynurenine/tryptophan (Kyn/Trp) ratio than lean or overweight women (P < 0." | 3.81 | Alterations of plasma metabolite profiles related to adipose tissue distribution and cardiometabolic risk. ( Adamski, J; Boulet, MM; Chevrier, G; Grenier-Larouche, T; Marette, A; Nadeau, M; Pelletier, M; Prehn, C; Scarpa, J; Tchernof, A, 2015) |
| "The treatment and prevention of migraine within the last decade has become largely pharmacological." | 1.43 | Migraine: A disorder of metabolism? ( Kokavec, A, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 5 (41.67) | 2.80 |
| Authors | Studies |
|---|---|
| Priyadarshini, M | 1 |
| Navarro, G | 1 |
| Reiman, DJ | 1 |
| Sharma, A | 1 |
| Xu, K | 1 |
| Lednovich, K | 1 |
| Manzella, CR | 1 |
| Khan, MW | 1 |
| Garcia, MS | 1 |
| Allard, S | 1 |
| Wicksteed, B | 1 |
| Chlipala, GE | 1 |
| Szynal, B | 1 |
| Bernabe, BP | 1 |
| Maki, PM | 1 |
| Gill, RK | 1 |
| Perdew, GH | 1 |
| Gilbert, J | 1 |
| Dai, Y | 1 |
| Layden, BT | 1 |
| Huang, T | 1 |
| Song, J | 1 |
| Gao, J | 1 |
| Cheng, J | 1 |
| Xie, H | 1 |
| Zhang, L | 1 |
| Wang, YH | 1 |
| Gao, Z | 1 |
| Wang, Y | 1 |
| Wang, X | 1 |
| He, J | 1 |
| Liu, S | 1 |
| Yu, Q | 1 |
| Zhang, S | 1 |
| Xiong, F | 1 |
| Zhou, Q | 1 |
| Wang, CY | 1 |
| Jasim, ZA | 1 |
| Al-Hakeim, HK | 1 |
| Zolghadri, S | 1 |
| Stanek, A | 1 |
| Oxenkrug, G | 3 |
| Summergrad, P | 2 |
| Boßlau, TK | 1 |
| Wasserfurth, P | 1 |
| Krüger, B | 1 |
| Reichel, T | 1 |
| Palmowski, J | 1 |
| Nebl, J | 1 |
| Weyh, C | 1 |
| Schenk, A | 1 |
| Joisten, N | 1 |
| Stahl, F | 1 |
| Thoms, S | 1 |
| Gebhardt, K | 1 |
| Hahn, A | 1 |
| Krüger, K | 1 |
| Muzik, O | 1 |
| Burghardt, P | 1 |
| Yi, Z | 1 |
| Kumar, A | 1 |
| Seyoum, B | 1 |
| Laurans, L | 1 |
| Venteclef, N | 1 |
| Haddad, Y | 1 |
| Chajadine, M | 1 |
| Alzaid, F | 1 |
| Metghalchi, S | 1 |
| Sovran, B | 1 |
| Denis, RGP | 1 |
| Dairou, J | 1 |
| Cardellini, M | 1 |
| Moreno-Navarrete, JM | 1 |
| Straub, M | 1 |
| Jegou, S | 1 |
| McQuitty, C | 1 |
| Viel, T | 1 |
| Esposito, B | 1 |
| Tavitian, B | 1 |
| Callebert, J | 1 |
| Luquet, SH | 1 |
| Federici, M | 1 |
| Fernandez-Real, JM | 1 |
| Burcelin, R | 1 |
| Launay, JM | 1 |
| Tedgui, A | 1 |
| Mallat, Z | 1 |
| Sokol, H | 1 |
| Taleb, S | 1 |
| Bernstein, HG | 1 |
| Guest, PC | 1 |
| van der Hart, M | 1 |
| Roeser, J | 1 |
| Steiner, J | 1 |
| Boulet, MM | 1 |
| Chevrier, G | 1 |
| Grenier-Larouche, T | 1 |
| Pelletier, M | 1 |
| Nadeau, M | 1 |
| Scarpa, J | 1 |
| Prehn, C | 1 |
| Marette, A | 1 |
| Adamski, J | 1 |
| Tchernof, A | 1 |
| Barat, P | 1 |
| Meiffred, MC | 1 |
| Brossaud, J | 1 |
| Fuchs, D | 1 |
| Corcuff, JB | 1 |
| Thibault, H | 1 |
| Capuron, L | 1 |
| Kokavec, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Very Low Calorie Ketogenic Diet on Microbiota, Adipose Tissue and Immunitary Regulation: Pilot Study on Patients With Metabolic Syndrome[NCT05275608] | 40 participants (Anticipated) | Interventional | 2022-11-07 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for kynurenine and Insulin Sensitivity
| Article | Year |
|---|---|
Insulin resistance and dysregulation of tryptophan-kynurenine and kynurenine-nicotinamide adenine dinucleotide metabolic pathways.
Topics: Biomarkers; Humans; Insulin Resistance; Kynurenine; Metabolic Networks and Pathways; NAD; Tryptophan | 2013 |
11 other studies available for kynurenine and Insulin Sensitivity
| Article | Year |
|---|---|
Gestational Insulin Resistance Is Mediated by the Gut Microbiome-Indoleamine 2,3-Dioxygenase Axis.
Topics: Animals; Female; Gastrointestinal Microbiome; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflamma | 2022 |
Adipocyte-derived kynurenine promotes obesity and insulin resistance by activating the AhR/STAT3/IL-6 signaling.
Topics: Adipocytes; Animals; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Insulin Resistance; Interleukin-6 | 2022 |
Maternal Tryptophan Catabolites and Insulin Resistance Parameters in Preeclampsia.
Topics: Case-Control Studies; Female; Humans; Insulin Resistance; Kynurenic Acid; Kynurenine; Pre-Eclampsia; | 2023 |
Benserazide, an Inhibitor of Peripheral Kynurenine Metabolism, Attenuates Olanzapine-Induced Weight Gain, Insulin Resistance, and Dyslipidemia in C57Bl/6j Mice.
Topics: Animals; Antipsychotic Agents; Benserazide; Dyslipidemias; Female; Insulin Resistance; Kynurenine; M | 2020 |
Abdominal Obesity-Related Disturbance of Insulin Sensitivity Is Associated with CD8
Topics: Adipokines; Biomarkers; Body Mass Index; Case-Control Studies; CD8-Positive T-Lymphocytes; Cross-Sec | 2021 |
Successful metformin treatment of insulin resistance is associated with down-regulation of the kynurenine pathway.
Topics: Adult; Down-Regulation; Humans; Insulin Resistance; Kynurenine; Metformin | 2017 |
Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health.
Topics: Animals; Diabetes Mellitus, Type 2; Fatty Liver; Gastrointestinal Microbiome; Health; Humans; Indole | 2018 |
Plasma xanthurenic acid in a context of insulin resistance and obesity in schizophrenia.
Topics: Case-Control Studies; Humans; Insulin Resistance; Kynurenic Acid; Kynurenine; Obesity; Schizophrenia | 2019 |
Alterations of plasma metabolite profiles related to adipose tissue distribution and cardiometabolic risk.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Adipocytes; Adipokines; Adipose Tissue; Adult; Am | 2015 |
Inflammatory, endocrine and metabolic correlates of fatigue in obese children.
Topics: Adolescent; Anhedonia; Apathy; Body Mass Index; C-Reactive Protein; Child; Fatigue; Female; Humans; | 2016 |
Migraine: A disorder of metabolism?
Topics: Animals; Eating; Fasting; Female; Food; Glucose; Glucose Transporter Type 3; Glucose Transporter Typ | 2016 |