Page last updated: 2024-10-18

kynurenine and Hypotension

kynurenine has been researched along with Hypotension in 4 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

ExcerptRelevanceReference
"Kynurenine is a potential contributor to hypotension in animal and human sepsis."7.81Kynurenine causes vasodilation and hypotension induced by activation of KCNQ-encoded voltage-dependent K(+) channels. ( Akahori, T; Feng, GG; Fujiwara, Y; Hatakeyama, N; Kinoshita, H; Li, J; Nakamura, E; Sakakibara, K; Yasuda, Y, 2015)
"Patients (n = 16) with septic shock had indoleamine 2,3-dioxygenase activity assessed as the kynurenine-to-tryptophan ratio, and the severity of hypotension was determined by their inotrope requirements."7.77Tryptophan metabolism to kynurenine is a potential novel contributor to hypotension in human sepsis. ( Celermajer, DS; Changsirivathanathamrong, D; dos Remedios, CG; Duflou, J; Gebski, V; Maghzal, GJ; Mak, WM; Rajbhandari, D; Stocker, R; Wang, Y; Woolfe, C, 2011)
"Kynurenine is a potential contributor to hypotension in animal and human sepsis."3.81Kynurenine causes vasodilation and hypotension induced by activation of KCNQ-encoded voltage-dependent K(+) channels. ( Akahori, T; Feng, GG; Fujiwara, Y; Hatakeyama, N; Kinoshita, H; Li, J; Nakamura, E; Sakakibara, K; Yasuda, Y, 2015)
"Patients (n = 16) with septic shock had indoleamine 2,3-dioxygenase activity assessed as the kynurenine-to-tryptophan ratio, and the severity of hypotension was determined by their inotrope requirements."3.77Tryptophan metabolism to kynurenine is a potential novel contributor to hypotension in human sepsis. ( Celermajer, DS; Changsirivathanathamrong, D; dos Remedios, CG; Duflou, J; Gebski, V; Maghzal, GJ; Mak, WM; Rajbhandari, D; Stocker, R; Wang, Y; Woolfe, C, 2011)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sakakibara, K1
Feng, GG1
Li, J1
Akahori, T1
Yasuda, Y1
Nakamura, E1
Hatakeyama, N1
Fujiwara, Y1
Kinoshita, H1
Changsirivathanathamrong, D1
Wang, Y1
Rajbhandari, D1
Maghzal, GJ1
Mak, WM1
Woolfe, C1
Duflou, J1
Gebski, V1
dos Remedios, CG1
Celermajer, DS1
Stocker, R1
Eiserich, JP1
Hayakawa, KA1
Cross, CE1
Oxenkrug, GF1

Other Studies

4 other studies available for kynurenine and Hypotension

ArticleYear
Kynurenine causes vasodilation and hypotension induced by activation of KCNQ-encoded voltage-dependent K(+) channels.
    Journal of pharmacological sciences, 2015, Volume: 129, Issue:1

    Topics: Animals; Arteries; Dose-Response Relationship, Drug; Humans; Hypotension; In Vitro Techniques; Indol

2015
Tryptophan metabolism to kynurenine is a potential novel contributor to hypotension in human sepsis.
    Critical care medicine, 2011, Volume: 39, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Hypotension; Indoleamine-Pyrrole 2,3,-Dioxygenase; I

2011
Sepsis and hypotension: enter kynurenine, move over nitric oxide.
    Critical care medicine, 2011, Volume: 39, Issue:12

    Topics: Female; Humans; Hypotension; Kynurenine; Male; Shock, Septic; Tryptophan

2011
Kynurenine and hypotension: historic perspectives.
    Critical care medicine, 2012, Volume: 40, Issue:6

    Topics: Female; Humans; Hypotension; Kynurenine; Male; Shock, Septic; Tryptophan

2012