kynurenine has been researched along with Genetic Predisposition in 6 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prior studies of mRNA expression, protein expression, and pathway metabolite levels have implicated dysregulation of the kynurenine pathway in the etiology of schizophrenia and bipolar disorder." | 7.75 | Two complex genotypes relevant to the kynurenine pathway and melanotropin function show association with schizophrenia and bipolar disorder. ( Leonard, S; Miller, CL; Murakami, P; Ross, RG; Ruczinski, I; Sinkus, M; Sullivan, B, 2009) |
| "Prior studies of mRNA expression, protein expression, and pathway metabolite levels have implicated dysregulation of the kynurenine pathway in the etiology of schizophrenia and bipolar disorder." | 3.75 | Two complex genotypes relevant to the kynurenine pathway and melanotropin function show association with schizophrenia and bipolar disorder. ( Leonard, S; Miller, CL; Murakami, P; Ross, RG; Ruczinski, I; Sinkus, M; Sullivan, B, 2009) |
| "PDS was determined by an Edinburgh Postnatal Depression Scale (EPDS) score ≥13." | 1.46 | Genetic variants of the kynurenine-3-monooxygenase and postpartum depressive symptoms after cesarean section in Chinese women. ( Duan, KM; Liu, ZQ; Mao, XY; Peng, C; Tan, XF; Wang, CY; Wang, SY; Yang, M; Yin, JY; Zheng, W; Zhou, HH, 2017) |
| "A consistent finding in major depressive disorder (MDD) research is dysfunction of the immune system." | 1.37 | The kynurenine pathway in major depression: haplotype analysis of three related functional candidate genes. ( Baune, B; Claes, S; De Deyn, P; Del-Favero, J; Domschke, K; Engelborghs, S; Entrich, K; Mueller, N; Myint, AM; Rothermundt, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 5 (83.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, SY | 1 |
| Duan, KM | 1 |
| Tan, XF | 1 |
| Yin, JY | 1 |
| Mao, XY | 1 |
| Zheng, W | 1 |
| Wang, CY | 1 |
| Yang, M | 1 |
| Peng, C | 1 |
| Zhou, HH | 1 |
| Liu, ZQ | 1 |
| Lee, A | 1 |
| Kanuri, N | 1 |
| Zhang, Y | 1 |
| Sayuk, GS | 1 |
| Li, E | 1 |
| Ciorba, MA | 1 |
| Miller, CL | 1 |
| Murakami, P | 1 |
| Ruczinski, I | 1 |
| Ross, RG | 1 |
| Sinkus, M | 1 |
| Sullivan, B | 1 |
| Leonard, S | 1 |
| Oxenkrug, GF | 1 |
| Claes, S | 1 |
| Myint, AM | 1 |
| Domschke, K | 1 |
| Del-Favero, J | 1 |
| Entrich, K | 1 |
| Engelborghs, S | 1 |
| De Deyn, P | 1 |
| Mueller, N | 1 |
| Baune, B | 1 |
| Rothermundt, M | 1 |
| Osawa, Y | 1 |
| Kanamori, H | 1 |
| Seki, E | 1 |
| Hoshi, M | 1 |
| Ohtaki, H | 1 |
| Yasuda, Y | 1 |
| Ito, H | 1 |
| Suetsugu, A | 1 |
| Nagaki, M | 1 |
| Moriwaki, H | 1 |
| Saito, K | 1 |
| Seishima, M | 1 |
1 review available for kynurenine and Genetic Predisposition
| Article | Year |
|---|---|
Tryptophan kynurenine metabolism as a common mediator of genetic and environmental impacts in major depressive disorder: the serotonin hypothesis revisited 40 years later.
Topics: Adrenal Cortex Hormones; Animals; Biosynthetic Pathways; Cytokines; Depressive Disorder, Major; Envi | 2010 |
5 other studies available for kynurenine and Genetic Predisposition
| Article | Year |
|---|---|
Genetic variants of the kynurenine-3-monooxygenase and postpartum depressive symptoms after cesarean section in Chinese women.
Topics: Adult; Asian People; Case-Control Studies; Cesarean Section; China; Depression, Postpartum; Female; | 2017 |
IDO1 and IDO2 non-synonymous gene variants: correlation with crohn's disease risk and clinical phenotype.
Topics: Adult; Case-Control Studies; Crohn Disease; Female; Genetic Predisposition to Disease; Humans; Indol | 2014 |
Two complex genotypes relevant to the kynurenine pathway and melanotropin function show association with schizophrenia and bipolar disorder.
Topics: Adult; Aged; Aged, 80 and over; Bipolar Disorder; Black or African American; Databases, Genetic; Fem | 2009 |
The kynurenine pathway in major depression: haplotype analysis of three related functional candidate genes.
Topics: Adult; Depressive Disorder, Major; Female; Gene Frequency; Genetic Predisposition to Disease; Haplot | 2011 |
L-tryptophan-mediated enhancement of susceptibility to nonalcoholic fatty liver disease is dependent on the mammalian target of rapamycin.
Topics: Adenoviridae; Animal Feed; Animals; Aromatic-L-Amino-Acid Decarboxylases; Fatty Liver; Fibrosis; Fru | 2011 |