Page last updated: 2024-10-18

kynurenine and Friedreich Ataxia

kynurenine has been researched along with Friedreich Ataxia in 2 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Friedreich Ataxia: An autosomal recessive disease, usually of childhood onset, characterized pathologically by degeneration of the spinocerebellar tracts, posterior columns, and to a lesser extent the corticospinal tracts. Clinical manifestations include GAIT ATAXIA, pes cavus, speech impairment, lateral curvature of spine, rhythmic head tremor, kyphoscoliosis, congestive heart failure (secondary to a cardiomyopathy), and lower extremity weakness. Most forms of this condition are associated with a mutation in a gene on chromosome 9, at band q13, which codes for the mitochondrial protein frataxin. (From Adams et al., Principles of Neurology, 6th ed, p1081; N Engl J Med 1996 Oct 17;335(16):1169-75) The severity of Friedreich ataxia associated with expansion of GAA repeats in the first intron of the frataxin gene correlates with the number of trinucleotide repeats. (From Durr et al, N Engl J Med 1996 Oct 17;335(16):1169-75)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
FISCHL, J1
RABIAH, S1
Robinson, N1
Curzon, G1
Theaker, P1

Other Studies

2 other studies available for kynurenine and Friedreich Ataxia

ArticleYear
DETERMINATION OF FREE AND TOTAL INDOLE-3-ACETIC ACID AND OF THE INDOLE INDEX.
    Clinical chemistry, 1964, Volume: 10

    Topics: Friedreich Ataxia; Humans; Indoleacetic Acids; Indoles; Intestines; Kynurenine; Metabolism; Myotonia

1964
Excretion of tryptophan metabolites in Friedreich's ataxia.
    Journal of clinical pathology, 1965, Volume: 18, Issue:6

    Topics: Friedreich Ataxia; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Kynurenine; Tryptophan; Uri

1965