kynurenine has been researched along with Fibromyalgia in 4 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fibromyalgia (FM) is a prevalent syndrome with chronic pain and a hypothesised underlying disturbance of the tryptophan (TRP) metabolism." | 7.72 | Experimental evaluation of an altered tryptophan metabolism in fibromyalgia. ( Ackenheil, M; Neumeister, A; Offenbaecher, M; Schwarz, MJ, 2003) |
| "Fibromyalgia (FM) is a prevalent syndrome with chronic pain and a hypothesized underlying disturbance of the tryptophan (TRP) metabolism." | 7.71 | Evidence for an altered tryptophan metabolism in fibromyalgia. ( Ackenheil, M; Ewert, T; Lossau, K; Neumeister, A; Offenbaecher, M; Praschak-Rieder, N; Schwarz, MJ; Stucki, G; Weisser, R; Willeit, M; Zach, J; Zacherl, M, 2002) |
| "The pathology of Chronic Fatigue Syndrome (CFS) and Fibromyalgia (FM) is currently under investigation, and the overlapping symptoms such as depression suggest that the CNS may be involved." | 5.62 | Kynurenine metabolites and ratios differ between Chronic Fatigue Syndrome, Fibromyalgia, and healthy controls. ( Fors, EA; Groven, N; Guzey, IC; Reitan, SK, 2021) |
| "Fibromyalgia (FM) is a prevalent syndrome with chronic pain and a hypothesised underlying disturbance of the tryptophan (TRP) metabolism." | 3.72 | Experimental evaluation of an altered tryptophan metabolism in fibromyalgia. ( Ackenheil, M; Neumeister, A; Offenbaecher, M; Schwarz, MJ, 2003) |
| "Fibromyalgia (FM) is a prevalent syndrome with chronic pain and a hypothesized underlying disturbance of the tryptophan (TRP) metabolism." | 3.71 | Evidence for an altered tryptophan metabolism in fibromyalgia. ( Ackenheil, M; Ewert, T; Lossau, K; Neumeister, A; Offenbaecher, M; Praschak-Rieder, N; Schwarz, MJ; Stucki, G; Weisser, R; Willeit, M; Zach, J; Zacherl, M, 2002) |
| "The pathology of Chronic Fatigue Syndrome (CFS) and Fibromyalgia (FM) is currently under investigation, and the overlapping symptoms such as depression suggest that the CNS may be involved." | 1.62 | Kynurenine metabolites and ratios differ between Chronic Fatigue Syndrome, Fibromyalgia, and healthy controls. ( Fors, EA; Groven, N; Guzey, IC; Reitan, SK, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pradeep, A | 1 |
| Birerdinc, A | 1 |
| Branigan, T | 1 |
| Phan, V | 1 |
| Morris, H | 1 |
| Shah, J | 1 |
| DeStefano, S | 1 |
| Sikdar, S | 1 |
| Srbely, J | 1 |
| Kumbhare, D | 1 |
| Stecco, A | 1 |
| Paik, J | 1 |
| Gerber, LH | 1 |
| Groven, N | 1 |
| Reitan, SK | 1 |
| Fors, EA | 1 |
| Guzey, IC | 1 |
| Schwarz, MJ | 2 |
| Offenbaecher, M | 2 |
| Neumeister, A | 2 |
| Ewert, T | 1 |
| Willeit, M | 1 |
| Praschak-Rieder, N | 1 |
| Zach, J | 1 |
| Zacherl, M | 1 |
| Lossau, K | 1 |
| Weisser, R | 1 |
| Stucki, G | 1 |
| Ackenheil, M | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect Of High Intensity Interval Upper Extremity Training On Biochemistry Parameters And Disease Symptoms In Patients With Fibromyalgia[NCT05502003] | 33 participants (Actual) | Interventional | 2022-08-25 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for kynurenine and Fibromyalgia
| Article | Year |
|---|---|
Evidence for an association of serum microanalytes and myofascial pain syndrome.
Topics: Acetylcholine; Adult; Brain-Derived Neurotrophic Factor; Cytokines; Dehydroepiandrosterone; Female; | 2023 |
Kynurenine metabolites and ratios differ between Chronic Fatigue Syndrome, Fibromyalgia, and healthy controls.
Topics: Adolescent; Adult; Case-Control Studies; Fatigue Syndrome, Chronic; Female; Fibromyalgia; Humans; Ky | 2021 |
Evidence for an altered tryptophan metabolism in fibromyalgia.
Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay | 2002 |
Experimental evaluation of an altered tryptophan metabolism in fibromyalgia.
Topics: Adult; Case-Control Studies; Cross-Over Studies; Double-Blind Method; Female; Fibromyalgia; Humans; | 2003 |