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kynurenine and Epilepsy, Temporal Lobe

kynurenine has been researched along with Epilepsy, Temporal Lobe in 5 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Epilepsy, Temporal Lobe: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).

Research Excerpts

ExcerptRelevanceReference
"Treatment with kynurenine inhibited glutamatergic activity in non-seizure control samples but not in MTLE-HS samples."5.62Altered hippocampal kynurenine pathway metabolism contributes to hyperexcitability in human mesial temporal lobe epilepsy-hippocampal sclerosis. ( Banerjee Dixit, A; Banerjee, J; Chandra, PS; Dey, S; Doddamani, RS; Lalwani, S; Sharma, MC; Tripathi, M, 2021)
"Treatment with kynurenine inhibited glutamatergic activity in non-seizure control samples but not in MTLE-HS samples."1.62Altered hippocampal kynurenine pathway metabolism contributes to hyperexcitability in human mesial temporal lobe epilepsy-hippocampal sclerosis. ( Banerjee Dixit, A; Banerjee, J; Chandra, PS; Dey, S; Doddamani, RS; Lalwani, S; Sharma, MC; Tripathi, M, 2021)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Dey, S4
Dubey, V3
Dixit, AB3
Tripathi, M4
Chandra, PS4
Banerjee, J4
Banerjee Dixit, A1
Doddamani, RS1
Sharma, MC1
Lalwani, S1
Natsume, J1
Kumakura, Y1
Bernasconi, N1
Soucy, JP1
Nakai, A1
Rosa, P1
Fedi, M1
Dubeau, F1
Andermann, F1
Lisbona, R1
Bernasconi, A1
Diksic, M1
Young, SN1
Joseph, MH1
Gauthier, S1
Schwarcz, R1
Du, F1

Reviews

1 review available for kynurenine and Epilepsy, Temporal Lobe

ArticleYear
Quinolinic acid and kynurenic acid in the mammalian brain.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; AIDS Dementia Complex; Animals; Aspartic Acid; Biological Tra

1991

Trials

1 trial available for kynurenine and Epilepsy, Temporal Lobe

ArticleYear
Alpha-[11C] methyl-L-tryptophan and glucose metabolism in patients with temporal lobe epilepsy.
    Neurology, 2003, Mar-11, Volume: 60, Issue:5

    Topics: Adolescent; Adult; Aged; Amygdala; Atrophy; Cerebral Cortex; Epilepsy, Temporal Lobe; Female; Glucos

2003

Other Studies

3 other studies available for kynurenine and Epilepsy, Temporal Lobe

ArticleYear
Differential Levels of Tryptophan-Kynurenine Pathway Metabolites in the Hippocampus, Anterior Temporal Lobe, and Neocortex in an Animal Model of Temporal Lobe Epilepsy.
    Cells, 2022, 11-10, Volume: 11, Issue:22

    Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kynurenic Acid; Kynurenine; N

2022
Differential Levels of Tryptophan-Kynurenine Pathway Metabolites in the Hippocampus, Anterior Temporal Lobe, and Neocortex in an Animal Model of Temporal Lobe Epilepsy.
    Cells, 2022, 11-10, Volume: 11, Issue:22

    Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kynurenic Acid; Kynurenine; N

2022
Differential Levels of Tryptophan-Kynurenine Pathway Metabolites in the Hippocampus, Anterior Temporal Lobe, and Neocortex in an Animal Model of Temporal Lobe Epilepsy.
    Cells, 2022, 11-10, Volume: 11, Issue:22

    Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kynurenic Acid; Kynurenine; N

2022
Differential Levels of Tryptophan-Kynurenine Pathway Metabolites in the Hippocampus, Anterior Temporal Lobe, and Neocortex in an Animal Model of Temporal Lobe Epilepsy.
    Cells, 2022, 11-10, Volume: 11, Issue:22

    Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kynurenic Acid; Kynurenine; N

2022
Differential Levels of Tryptophan-Kynurenine Pathway Metabolites in the Hippocampus, Anterior Temporal Lobe, and Neocortex in an Animal Model of Temporal Lobe Epilepsy.
    Cells, 2022, 11-10, Volume: 11, Issue:22

    Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kynurenic Acid; Kynurenine; N

2022
Differential Levels of Tryptophan-Kynurenine Pathway Metabolites in the Hippocampus, Anterior Temporal Lobe, and Neocortex in an Animal Model of Temporal Lobe Epilepsy.
    Cells, 2022, 11-10, Volume: 11, Issue:22

    Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kynurenic Acid; Kynurenine; N

2022
Differential Levels of Tryptophan-Kynurenine Pathway Metabolites in the Hippocampus, Anterior Temporal Lobe, and Neocortex in an Animal Model of Temporal Lobe Epilepsy.
    Cells, 2022, 11-10, Volume: 11, Issue:22

    Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kynurenic Acid; Kynurenine; N

2022
Differential Levels of Tryptophan-Kynurenine Pathway Metabolites in the Hippocampus, Anterior Temporal Lobe, and Neocortex in an Animal Model of Temporal Lobe Epilepsy.
    Cells, 2022, 11-10, Volume: 11, Issue:22

    Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kynurenic Acid; Kynurenine; N

2022
Differential Levels of Tryptophan-Kynurenine Pathway Metabolites in the Hippocampus, Anterior Temporal Lobe, and Neocortex in an Animal Model of Temporal Lobe Epilepsy.
    Cells, 2022, 11-10, Volume: 11, Issue:22

    Topics: Animals; Disease Models, Animal; Epilepsy, Temporal Lobe; Hippocampus; Kynurenic Acid; Kynurenine; N

2022
Altered hippocampal kynurenine pathway metabolism contributes to hyperexcitability in human mesial temporal lobe epilepsy-hippocampal sclerosis.
    British journal of pharmacology, 2021, Volume: 178, Issue:19

    Topics: Chromatography, Liquid; Epilepsy, Temporal Lobe; Hippocampus; Humans; Kynurenine; Magnetic Resonance

2021
Studies on kynurenine in human cerebrospinal fluid: lowered levels in epilepsy.
    Journal of neural transmission, 1983, Volume: 58, Issue:3-4

    Topics: Adolescent; Adult; Aged; Amino Acids; Anticonvulsants; Epilepsy; Epilepsy, Temporal Lobe; Humans; Hy

1983