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kynurenine and Eosinophilia-Myalgia Syndrome

kynurenine has been researched along with Eosinophilia-Myalgia Syndrome in 4 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Eosinophilia-Myalgia Syndrome: A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. Diagnostic features generally include EOSINOPHILIA, myalgia severe enough to limit usual activities of daily living, and the absence of coexisting infectious, autoimmune or other conditions that may induce eosinophilia. Biopsy of affected tissue reveals a microangiopathy associated with diffuse inflammation involving connective tissue. (From Spitzer et al., J Rheumatol Suppl 1996 Oct;46:73-9; Blackburn WD, Semin Arthritis Rheum 1997 Jun;26(6):788-93)

Research Excerpts

ExcerptRelevanceReference
"We report a L-tryptophan-induced case of eosinophilia-myalgia syndrome in a Japanese woman and describe the time course of changes in tryptophan metabolism observed during steroid therapy."7.69Elevated L-kynurenine level and its normalization by prednisolone in a patient with eosinophilia-myalgia syndrome. ( Hisatomi, A; Imamura, T; Kubota, A; Nagata, T; Nawata, H; Ohashi, M; Umeda, F, 1997)
"To investigate the metabolism of L-tryptophan (LT) via the kynurenine pathway in patients with the eosinophilia-myalgia syndrome (EMS)."7.68Tryptophan metabolism via the kynurenine pathway in patients with the eosinophilia-myalgia syndrome. ( Harati, Y; Heyes, MP; McKinley, K; Quearry, B; Silver, RM; Smith, EA; Sternberg, EM, 1992)
"The eosinophilia-myalgia syndrome (EMS) was associated with ingestion of L-tryptophan containing products and was accompanied by altered metabolism of L-tryptophan during the active phase."7.68Alterations in tryptophan metabolism in the toxic oil syndrome and in the eosinophilia-myalgia syndrome. ( Carreira, P; Heyes, MP; Silver, RM; Sutherland, SE, 1992)
"Abnormal metabolism of tryptophan is one of the possible aetiological factors in the L-tryptophan-induced eosinophilia-myalgia syndrome (EMS)."7.68L-tryptophan-induced eosinophilia-myalgia syndrome. II. Partial correction of abnormal tryptophan metabolism by pyridoxine. ( Fathi, M; Mainetti, C; Saurat, JH, 1991)
"We report a L-tryptophan-induced case of eosinophilia-myalgia syndrome in a Japanese woman and describe the time course of changes in tryptophan metabolism observed during steroid therapy."3.69Elevated L-kynurenine level and its normalization by prednisolone in a patient with eosinophilia-myalgia syndrome. ( Hisatomi, A; Imamura, T; Kubota, A; Nagata, T; Nawata, H; Ohashi, M; Umeda, F, 1997)
"To investigate the metabolism of L-tryptophan (LT) via the kynurenine pathway in patients with the eosinophilia-myalgia syndrome (EMS)."3.68Tryptophan metabolism via the kynurenine pathway in patients with the eosinophilia-myalgia syndrome. ( Harati, Y; Heyes, MP; McKinley, K; Quearry, B; Silver, RM; Smith, EA; Sternberg, EM, 1992)
"The eosinophilia-myalgia syndrome (EMS) was associated with ingestion of L-tryptophan containing products and was accompanied by altered metabolism of L-tryptophan during the active phase."3.68Alterations in tryptophan metabolism in the toxic oil syndrome and in the eosinophilia-myalgia syndrome. ( Carreira, P; Heyes, MP; Silver, RM; Sutherland, SE, 1992)
"Abnormal metabolism of tryptophan is one of the possible aetiological factors in the L-tryptophan-induced eosinophilia-myalgia syndrome (EMS)."3.68L-tryptophan-induced eosinophilia-myalgia syndrome. II. Partial correction of abnormal tryptophan metabolism by pyridoxine. ( Fathi, M; Mainetti, C; Saurat, JH, 1991)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hisatomi, A1
Kubota, A1
Ohashi, M1
Umeda, F1
Nawata, H1
Imamura, T1
Nagata, T1
Silver, RM2
McKinley, K1
Smith, EA1
Quearry, B1
Harati, Y1
Sternberg, EM1
Heyes, MP2
Sutherland, SE1
Carreira, P1
Mainetti, C1
Fathi, M1
Saurat, JH1

Other Studies

4 other studies available for kynurenine and Eosinophilia-Myalgia Syndrome

ArticleYear
Elevated L-kynurenine level and its normalization by prednisolone in a patient with eosinophilia-myalgia syndrome.
    Fukuoka igaku zasshi = Hukuoka acta medica, 1997, Volume: 88, Issue:1

    Topics: Anti-Inflammatory Agents; Eosinophilia-Myalgia Syndrome; Female; Humans; Kynurenine; Middle Aged; Pr

1997
Tryptophan metabolism via the kynurenine pathway in patients with the eosinophilia-myalgia syndrome.
    Arthritis and rheumatism, 1992, Volume: 35, Issue:9

    Topics: Adrenal Cortex Hormones; Adult; Aged; Eosinophilia-Myalgia Syndrome; Female; Humans; Interferon-gamm

1992
Alterations in tryptophan metabolism in the toxic oil syndrome and in the eosinophilia-myalgia syndrome.
    The Journal of rheumatology, 1992, Volume: 19, Issue:1

    Topics: Arthritis, Rheumatoid; Biopterins; Brassica; Eosinophilia-Myalgia Syndrome; Fatty Acids, Monounsatur

1992
L-tryptophan-induced eosinophilia-myalgia syndrome. II. Partial correction of abnormal tryptophan metabolism by pyridoxine.
    Dermatologica, 1991, Volume: 183, Issue:1

    Topics: Adult; Eosinophilia-Myalgia Syndrome; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Middle A

1991