kynurenine has been researched along with Diathesis in 14 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It has been shown that a possible pathogenetic mechanism of neurodegeneration in the mouse model of glaucoma (DBA/2J) may be an alteration of kynurenic acid (KYNA) in the retina." | 8.02 | Tryptophan Pathway Abnormalities in a Murine Model of Hereditary Glaucoma. ( Avitabile, T; Choragiewicz, T; Fiedorowicz, M; Grieb, P; Kamińska, A; Kocki, T; Nowakowska, D; Rejdak, R; Toro, MD; Turski, WA; Wertejuk, K; Wełniak-Kaminska, M; Zweifel, S, 2021) |
| "Obesity is a metabolic disease characterized by a state of chronic, low-grade inflammation and dominated by pro-inflammatory cytokines such as IL-6." | 5.62 | Pathogenetic Interplay Between IL-6 and Tryptophan Metabolism in an Experimental Model of Obesity. ( Albini, E; Belladonna, ML; Grohmann, U; Mondanelli, G; Orabona, C; Orecchini, E; Pallotta, MT; Ricci, G, 2021) |
| " We review the literature concerning SARS-CoV2 infiltration and infection in the CNS and the prospects of synergy between stress, inflammation, and kynurenine pathway function during illness and recovery from Covid-19." | 5.12 | Covid-19 interface with drug misuse and substance use disorders. ( Cisneros, IE; Cunningham, KA, 2021) |
| "It has been shown that a possible pathogenetic mechanism of neurodegeneration in the mouse model of glaucoma (DBA/2J) may be an alteration of kynurenic acid (KYNA) in the retina." | 4.02 | Tryptophan Pathway Abnormalities in a Murine Model of Hereditary Glaucoma. ( Avitabile, T; Choragiewicz, T; Fiedorowicz, M; Grieb, P; Kamińska, A; Kocki, T; Nowakowska, D; Rejdak, R; Toro, MD; Turski, WA; Wertejuk, K; Wełniak-Kaminska, M; Zweifel, S, 2021) |
| "Primary brain tumors, both malignant and benign, are diagnosed in adults at an incidence rate of approximately 23 people per 100 thousand." | 2.66 | The Role of Aryl Hydrocarbon Receptor (AhR) in Brain Tumors. ( Grishanova, AY; Perepechaeva, ML, 2020) |
| "Obesity is a metabolic disease characterized by a state of chronic, low-grade inflammation and dominated by pro-inflammatory cytokines such as IL-6." | 1.62 | Pathogenetic Interplay Between IL-6 and Tryptophan Metabolism in an Experimental Model of Obesity. ( Albini, E; Belladonna, ML; Grohmann, U; Mondanelli, G; Orabona, C; Orecchini, E; Pallotta, MT; Ricci, G, 2021) |
| "Paracoccidioides brasiliensis infection was more severe in 1MT treated than untreated macrophages of resistant and susceptible mice, concurrently with decreased production of kynurenines and IDO mRNA." | 1.40 | Indoleamine 2,3-dioxygenase controls fungal loads and immunity in Paracoccidioidomicosis but is more important to susceptible than resistant hosts. ( Araújo, EF; Bazan, SB; Calich, VL; Costa, TA; Feriotti, C; Loures, FV; Pina, A; Schanoski, AS, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 7 (50.00) | 24.3611 |
| 2020's | 6 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Skorobogatov, K | 1 |
| De Picker, L | 1 |
| Verkerk, R | 1 |
| Coppens, V | 1 |
| Leboyer, M | 1 |
| Müller, N | 1 |
| Morrens, M | 1 |
| Zádor, F | 2 |
| Nagy-Grócz, G | 2 |
| Kekesi, G | 1 |
| Dvorácskó, S | 2 |
| Szűcs, E | 2 |
| Tömböly, C | 2 |
| Horvath, G | 1 |
| Benyhe, S | 2 |
| Vécsei, L | 4 |
| Boros, FA | 1 |
| Perepechaeva, ML | 1 |
| Grishanova, AY | 1 |
| Fiedorowicz, M | 1 |
| Choragiewicz, T | 1 |
| Turski, WA | 1 |
| Kocki, T | 1 |
| Nowakowska, D | 1 |
| Wertejuk, K | 1 |
| Kamińska, A | 1 |
| Avitabile, T | 1 |
| Wełniak-Kaminska, M | 1 |
| Grieb, P | 1 |
| Zweifel, S | 1 |
| Rejdak, R | 1 |
| Toro, MD | 1 |
| Joca, S | 1 |
| Mondanelli, G | 1 |
| Albini, E | 1 |
| Orecchini, E | 1 |
| Pallotta, MT | 1 |
| Belladonna, ML | 1 |
| Ricci, G | 1 |
| Grohmann, U | 1 |
| Orabona, C | 1 |
| Cisneros, IE | 1 |
| Cunningham, KA | 1 |
| Sas, K | 1 |
| Szabó, E | 1 |
| Araújo, EF | 1 |
| Loures, FV | 2 |
| Bazan, SB | 2 |
| Feriotti, C | 2 |
| Pina, A | 2 |
| Schanoski, AS | 1 |
| Costa, TA | 1 |
| Calich, VL | 2 |
| Zelante, T | 2 |
| Pieraccini, G | 1 |
| Scaringi, L | 1 |
| Aversa, F | 2 |
| Romani, L | 2 |
| de Luca, A | 1 |
| Bozza, S | 1 |
| Zagarella, S | 1 |
| D'Angelo, C | 1 |
| Perruccio, K | 1 |
| Vacca, C | 1 |
| Carvalho, A | 1 |
| Cunha, C | 1 |
| Felonato, M | 1 |
| de Araujo, EF | 1 |
| Silva, NM | 1 |
| Rodrigues, CV | 1 |
| Santoro, MM | 1 |
| Reis, LF | 1 |
| Alvarez-Leite, JI | 1 |
| Gazzinelli, RT | 1 |
8 reviews available for kynurenine and Diathesis
| Article | Year |
|---|---|
Brain
Topics: Animals; Biomarkers; Blood-Brain Barrier; Brain; Disease Models, Animal; Disease Susceptibility; Hum | 2021 |
Kynurenines and the Endocannabinoid System in Schizophrenia: Common Points and Potential Interactions.
Topics: Animals; Biomarkers; Disease Susceptibility; Endocannabinoids; Humans; Kynurenine; Metabolic Network | 2019 |
Immunomodulatory Effects of Genetic Alterations Affecting the Kynurenine Pathway.
Topics: Animals; Biomarkers; Disease Susceptibility; Gene Expression Regulation, Enzymologic; Genetic Variat | 2019 |
The Role of Aryl Hydrocarbon Receptor (AhR) in Brain Tumors.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Brain Neoplasms; Disease Management; Disease | 2020 |
Pro-Inflammatory Cytokines: Potential Links between the Endocannabinoid System and the Kynurenine Pathway in Depression.
Topics: Animals; Biomarkers; Cytokines; Depression; Disease Susceptibility; Endocannabinoids; Humans; Inflam | 2021 |
Covid-19 interface with drug misuse and substance use disorders.
Topics: Adaptation, Psychological; Angiotensin-Converting Enzyme 2; Animals; Axons; Comorbidity; COVID-19; D | 2021 |
Mitochondria, Oxidative Stress and the Kynurenine System, with a Focus on Ageing and Neuroprotection.
Topics: Aging; Animals; Brain; Cellular Senescence; Disease Susceptibility; DNA Damage; DNA Repair; DNA, Mit | 2018 |
Learning from other diseases: protection and pathology in chronic fungal infections.
Topics: Animals; Disease Resistance; Disease Susceptibility; Fungi; Host-Pathogen Interactions; Humans; Immu | 2016 |
6 other studies available for kynurenine and Diathesis
| Article | Year |
|---|---|
Tryptophan Pathway Abnormalities in a Murine Model of Hereditary Glaucoma.
Topics: Animals; Biomarkers; Disease Models, Animal; Disease Susceptibility; Genetic Diseases, Inborn; Glauc | 2021 |
Pathogenetic Interplay Between IL-6 and Tryptophan Metabolism in an Experimental Model of Obesity.
Topics: Adipose Tissue; Animals; Biomarkers; Cytokines; Diet, High-Fat; Disease Models, Animal; Disease Susc | 2021 |
Indoleamine 2,3-dioxygenase controls fungal loads and immunity in Paracoccidioidomicosis but is more important to susceptible than resistant hosts.
Topics: Animals; Cytokines; Dendritic Cells; Disease Susceptibility; Host-Pathogen Interactions; Indoleamine | 2014 |
Non-hematopoietic cells contribute to protective tolerance to Aspergillus fumigatus via a TRIF pathway converging on IDO.
Topics: Adaptor Proteins, Vesicular Transport; Animals; Aspergillus fumigatus; Disease Susceptibility; Down- | 2010 |
Anti-CD25 treatment depletes Treg cells and decreases disease severity in susceptible and resistant mice infected with Paracoccidioides brasiliensis.
Topics: Animals; Antibodies; Cell Movement; Disease Resistance; Disease Susceptibility; Forkhead Transcripti | 2012 |
Expression of indoleamine 2,3-dioxygenase, tryptophan degradation, and kynurenine formation during in vivo infection with Toxoplasma gondii: induction by endogenous gamma interferon and requirement of interferon regulatory factor 1.
Topics: Acute Disease; Animals; Disease Susceptibility; DNA-Binding Proteins; Gene Expression; Interferon Re | 2002 |