kynurenine has been researched along with Diarrhea in 7 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The purpose of this study was to evaluate the efficacy of a low-FODMAP diet with a concomitant reduction in tryptophan (TRP) intake in irritable bowel syndrome with diarrhea predominance (IBS-D) in relation to its metabolism via the serotonin and kynurenine pathways." | 9.69 | The Usefulness of the Low-FODMAP Diet with Limited Tryptophan Intake in the Treatment of Diarrhea-Predominant Irritable Bowel Syndrome. ( Blasiak, J; Blonska, A; Chojnacki, C; Chojnacki, J; Konrad, P; Poplawski, T, 2023) |
| "Irregularities of serotonin function in irritable bowel syndrome (IBS) may be due to changes in the metabolism of the serotonin precursor l-tryptophan." | 9.14 | Increased serum free tryptophan in patients with diarrhea-predominant irritable bowel syndrome. ( Afzal, M; Badawy, AA; Christmas, DM; Creed, T; Davies, SJ; Hince, D; Nutt, DJ; Potokar, JP; Probert, C; Smithson, J, 2010) |
| "Our objectives are to demonstrate whether the kynurenine pathway is activated in diarrhea-type irritable bowel syndrome (IBS-D) patients, and whether the neurotoxic metabolite quinolinic acid (QUIN) is out of balance with the neuroprotective metabolite kynurenic acid (KYNA), and further explore whether this can lead to increase of N-methyl D-aspartate receptor 2B (NMDAR2B) expression in the enteric nervous system and in turn leads to intestinal symptoms and mood disorders." | 7.96 | Characterization of kynurenine pathway in patients with diarrhea-predominant irritable bowel syndrome. ( Bai, Y; Cui, Z; Li, P; Li, Y; Wang, D; Wang, Y; Zhang, J; Zheng, J, 2020) |
| " The purpose of this study was to evaluate the efficacy of a low-FODMAP diet with a concomitant reduction in tryptophan (TRP) intake in irritable bowel syndrome with diarrhea predominance (IBS-D) in relation to its metabolism via the serotonin and kynurenine pathways." | 5.69 | The Usefulness of the Low-FODMAP Diet with Limited Tryptophan Intake in the Treatment of Diarrhea-Predominant Irritable Bowel Syndrome. ( Blasiak, J; Blonska, A; Chojnacki, C; Chojnacki, J; Konrad, P; Poplawski, T, 2023) |
| "Irregularities of serotonin function in irritable bowel syndrome (IBS) may be due to changes in the metabolism of the serotonin precursor l-tryptophan." | 5.14 | Increased serum free tryptophan in patients with diarrhea-predominant irritable bowel syndrome. ( Afzal, M; Badawy, AA; Christmas, DM; Creed, T; Davies, SJ; Hince, D; Nutt, DJ; Potokar, JP; Probert, C; Smithson, J, 2010) |
| "Our objectives are to demonstrate whether the kynurenine pathway is activated in diarrhea-type irritable bowel syndrome (IBS-D) patients, and whether the neurotoxic metabolite quinolinic acid (QUIN) is out of balance with the neuroprotective metabolite kynurenic acid (KYNA), and further explore whether this can lead to increase of N-methyl D-aspartate receptor 2B (NMDAR2B) expression in the enteric nervous system and in turn leads to intestinal symptoms and mood disorders." | 3.96 | Characterization of kynurenine pathway in patients with diarrhea-predominant irritable bowel syndrome. ( Bai, Y; Cui, Z; Li, P; Li, Y; Wang, D; Wang, Y; Zhang, J; Zheng, J, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Das, R | 1 |
| Haque, MA | 1 |
| Sobi, RA | 1 |
| Sultana, AA | 1 |
| Khan, MA | 1 |
| Gazi, A | 1 |
| Mahfuz, M | 1 |
| Nahar, B | 1 |
| Bardhan, PK | 1 |
| Ahmed, T | 1 |
| Chojnacki, C | 1 |
| Poplawski, T | 1 |
| Blonska, A | 1 |
| Konrad, P | 1 |
| Chojnacki, J | 1 |
| Blasiak, J | 1 |
| Li, P | 1 |
| Zheng, J | 1 |
| Bai, Y | 1 |
| Wang, D | 1 |
| Cui, Z | 1 |
| Li, Y | 1 |
| Zhang, J | 1 |
| Wang, Y | 1 |
| Capozzalo, MM | 1 |
| Kim, JC | 1 |
| Htoo, JK | 1 |
| de Lange, CF | 1 |
| Mullan, BP | 1 |
| Hansen, CF | 1 |
| Resink, JW | 1 |
| Stumbles, PA | 1 |
| Hampson, DJ | 1 |
| Pluske, JR | 1 |
| Christmas, DM | 1 |
| Badawy, AA | 1 |
| Hince, D | 1 |
| Davies, SJ | 1 |
| Probert, C | 1 |
| Creed, T | 1 |
| Smithson, J | 1 |
| Afzal, M | 1 |
| Nutt, DJ | 1 |
| Potokar, JP | 1 |
| Montenero, AS | 1 |
| Lapin, IP | 1 |
3 trials available for kynurenine and Diarrhea
| Article | Year |
|---|---|
The Usefulness of the Low-FODMAP Diet with Limited Tryptophan Intake in the Treatment of Diarrhea-Predominant Irritable Bowel Syndrome.
Topics: Chromatography, Liquid; Diarrhea; Diet; Fermentation; FODMAP Diet; Humans; Irritable Bowel Syndrome; | 2023 |
Effect of increasing the dietary tryptophan to lysine ratio on plasma levels of tryptophan, kynurenine and urea and on production traits in weaner pigs experimentally infected with an enterotoxigenic strain of Escherichia coli.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Bacterial Shedding; Body Weight; D | 2015 |
Increased serum free tryptophan in patients with diarrhea-predominant irritable bowel syndrome.
Topics: Adult; Affect; Amino Acids, Neutral; Case-Control Studies; Dairy Products; Diarrhea; Diet; Female; H | 2010 |
4 other studies available for kynurenine and Diarrhea
| Article | Year |
|---|---|
Citrulline and kynurenine to tryptophan ratio: potential EED (environmental enteric dysfunction) biomarkers in acute watery diarrhea among children in Bangladesh.
Topics: Bangladesh; Biomarkers; Child, Preschool; Citrulline; Cross-Sectional Studies; Diarrhea; Humans; Inf | 2023 |
Characterization of kynurenine pathway in patients with diarrhea-predominant irritable bowel syndrome.
Topics: Diarrhea; Female; Humans; Intestinal Mucosa; Irritable Bowel Syndrome; Kynurenic Acid; Kynurenine; M | 2020 |
[Toxicity and tolerance of tryptophan and its metabolites].
Topics: Animals; Cats; Diarrhea; Dogs; Guinea Pigs; Humans; Kynurenine; Mice; ortho-Aminobenzoates; Rabbits; | 1978 |
Interaction of kynurenine and its metabolites with tryptamine, serotonin and its precursors and oxotremorine.
Topics: Animals; Behavior, Animal; Diarrhea; Drug Antagonism; Drug Interactions; Female; Humans; Hypothermia | 1972 |