kynurenine has been researched along with Diabetic Retinopathy in 2 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An elevation in the concentrations of tryptophan metabolites and IDO expression was evident in diabetic retinopathy patients." | 7.77 | Evaluation of indoleamine 2,3-dioxygenase expression and kynurenine pathway metabolites levels in serum samples of diabetic retinopathy patients. ( Agraharm, SG; Gundae, S; Munipally, PK; Turlapati, NR; Valavala, VK, 2011) |
| "An elevation in the concentrations of tryptophan metabolites and IDO expression was evident in diabetic retinopathy patients." | 3.77 | Evaluation of indoleamine 2,3-dioxygenase expression and kynurenine pathway metabolites levels in serum samples of diabetic retinopathy patients. ( Agraharm, SG; Gundae, S; Munipally, PK; Turlapati, NR; Valavala, VK, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| KozieĊ, K | 1 |
| Urbanska, EM | 1 |
| Munipally, PK | 1 |
| Agraharm, SG | 1 |
| Valavala, VK | 1 |
| Gundae, S | 1 |
| Turlapati, NR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Vortioxetine Monotherapy for Major Depressive Disorder in Type 2 Diabetes: Role of Inflammation, Kynurenine Pathway, and Structural and Functional Brain Connectivity as Biomarkers[NCT03580967] | Phase 4 | 0 participants (Actual) | Interventional | 2019-07-01 | Withdrawn (stopped due to COVID-19 Pandemic interfered with Pt recruitment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for kynurenine and Diabetic Retinopathy
| Article | Year |
|---|---|
Kynurenine Pathway in Diabetes Mellitus-Novel Pharmacological Target?
Topics: Animals; Brain; Diabetes Mellitus; Diabetic Retinopathy; Humans; Kynurenine; Nervous System Diseases | 2023 |
1 other study available for kynurenine and Diabetic Retinopathy
| Article | Year |
|---|---|
Evaluation of indoleamine 2,3-dioxygenase expression and kynurenine pathway metabolites levels in serum samples of diabetic retinopathy patients.
Topics: Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Diabetic Retinopathy; Female | 2011 |