Page last updated: 2024-10-18

kynurenine and Diabetes Mellitus

kynurenine has been researched along with Diabetes Mellitus in 15 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.

Research Excerpts

ExcerptRelevanceReference
"Although we are far from a complete understanding of the role of kynurenine pathway in the modulation of energy homeostasis, targeting kynurenine pathway harbors high potential to expand the range of therapies to prevent and treat metabolic diseases."5.01Emerging role for kynurenines in metabolic pathologies. ( Liu, JJ; Movassat, J; Portha, B, 2019)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19909 (60.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.67)29.6817
2010's4 (26.67)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Kozieł, K1
Urbanska, EM1
Song, P1
Ramprasath, T1
Wang, H1
Zou, MH1
Entenmann, L1
Pietzner, M1
Artati, A1
Hannemann, A1
Henning, AK1
Kastenmüller, G1
Völzke, H1
Nauck, M1
Adamski, J1
Wallaschofski, H1
Friedrich, N1
Liu, JJ1
Movassat, J1
Portha, B1
Favennec, M1
Hennart, B1
Verbanck, M1
Pigeyre, M1
Caiazzo, R1
Raverdy, V1
Verkindt, H1
Leloire, A1
Guillemin, GJ1
Yengo, L1
Allorge, D1
Froguel, P1
Pattou, F1
Poulain-Godefroy, O1
MUSAJO, L1
BENASSI, CA1
PASQUARIELLO, G1
Belladonna, ML1
Puccetti, P1
Orabona, C1
Fallarino, F1
Vacca, C1
Volpi, C1
Gizzi, S1
Pallotta, MT1
Fioretti, MC1
Grohmann, U1
Rudzit, VK1
Silinia, IIa1
Connick, JH1
Stone, TW1
Kniazev, IuA1
Marchenko, LF1
Vakhrusheva, LL1
Denisov, BE1
Chiancone, FM1
Okamoto, H1
Tabolin, VA1
Kruglov, BV1
Lebedev, VP1
Levitina, NO1
Khattab, M1
Abul-Fadl, M1
Khalafallah, A1
Hamza, S1

Reviews

6 reviews available for kynurenine and Diabetes Mellitus

ArticleYear
Kynurenine Pathway in Diabetes Mellitus-Novel Pharmacological Target?
    Cells, 2023, 01-31, Volume: 12, Issue:3

    Topics: Animals; Brain; Diabetes Mellitus; Diabetic Retinopathy; Humans; Kynurenine; Nervous System Diseases

2023
Abnormal kynurenine pathway of tryptophan catabolism in cardiovascular diseases.
    Cellular and molecular life sciences : CMLS, 2017, Volume: 74, Issue:16

    Topics: Aging; Animals; Blood Pressure; Cardiovascular Diseases; Diabetes Mellitus; Drug Discovery; Endothel

2017
Emerging role for kynurenines in metabolic pathologies.
    Current opinion in clinical nutrition and metabolic care, 2019, Volume: 22, Issue:1

    Topics: Aging; Animals; Atherosclerosis; Biomarkers; Diabetes Mellitus; Homeostasis; Humans; Islets of Lange

2019
ASPECTS OF DISORDERS OF THE KYNURENINE PATHWAY OF TRYPTOPHAN METABOLISM IN MAN.
    Advances in clinical chemistry, 1964, Volume: 7

    Topics: Amino Acids; Diabetes Mellitus; Fluids and Secretions; Geriatrics; Hodgkin Disease; Humans; Kidney C

1964
[On the regulatory mechanism of kynurenine metabolism in mitochondrial membranes with special reference to the problem of hyperinsulinemia or diabetic state (author's transl)].
    Seikagaku. The Journal of Japanese Biochemical Society, 1974, Sep-25, Volume: 46, Issue:9

    Topics: Animals; Diabetes Mellitus; Electron Transport; Female; Flavin-Adenine Dinucleotide; Glucose; Humans

1974
[Chief clinical syndromes in children with tryptophan metabolism disorders (literature survey)].
    Voprosy okhrany materinstva i detstva, 1972, Volume: 17, Issue:6

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Carboxy-Lyases; Child; Child, Preschool; Diabetes

1972

Trials

1 trial available for kynurenine and Diabetes Mellitus

ArticleYear
Comprehensive metabolic characterization of serum osteocalcin action in a large non-diabetic sample.
    PloS one, 2017, Volume: 12, Issue:9

    Topics: Adult; Aged; Biomarkers; Diabetes Mellitus; Female; Germany; Humans; Kidney; Kidney Function Tests;

2017

Other Studies

8 other studies available for kynurenine and Diabetes Mellitus

ArticleYear
Post-Bariatric Surgery Changes in Quinolinic and Xanthurenic Acid Concentrations Are Associated with Glucose Homeostasis.
    PloS one, 2016, Volume: 11, Issue:6

    Topics: Adult; Bariatric Surgery; C-Reactive Protein; Diabetes Mellitus; Female; Glucose; Homeostasis; Human

2016
[RESEARCH ON THE TRYPTOPHAN--NICOTINIC ACID PATHWAY IN DIABETES MELLITUS].
    Acta vitaminologica, 1964, Volume: 18

    Topics: Diabetes Mellitus; Geriatrics; Hippurates; Insulin; Kynurenic Acid; Kynurenine; Metabolism; Niacin;

1964
Immunosuppression via tryptophan catabolism: the role of kynurenine pathway enzymes.
    Transplantation, 2007, Jul-15, Volume: 84, Issue:1 Suppl

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antigens, CD; Antigens, Differentiation; CTLA-4 Antig

2007
[Method of determination of blood serum kynurenine content].
    Laboratornoe delo, 1980, Issue:4

    Topics: Adolescent; Adult; Cushing Syndrome; Diabetes Mellitus; Female; Humans; Hyperthyroidism; Kynurenine;

1980
The role of kynurenines in diabetes mellitus.
    Medical hypotheses, 1985, Volume: 18, Issue:4

    Topics: Diabetes Mellitus; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Kynurenine

1985
[Chromatographic separation of tryptophan metabolites on thin-layer silica gel].
    Laboratornoe delo, 1971, Volume: 2

    Topics: Adolescent; Child; Chromatography, Thin Layer; Diabetes Mellitus; Gels; Humans; Indoleacetic Acids;

1971
[Functional exploration at various levels of the tryptophan--nicotinic acid metabolic line].
    Acta vitaminologica et enzymologica, 1972, Volume: 26, Issue:3

    Topics: Diabetes Mellitus; Down Syndrome; Female; Humans; Hydroxyindoleacetic Acid; Hydroxylation; Kynurenin

1972
Studies on the urinary excretion of certain tryptophan metabolites in diabetics.
    The Journal of the Egyptian Medical Association, 1972, Volume: 55, Issue:7

    Topics: Adolescent; Adult; Amino Acids; Diabetes Mellitus; Female; Humans; Hydroxyindoleacetic Acid; Kynuren

1972