Page last updated: 2024-10-18

kynurenine and Depression, Postpartum

kynurenine has been researched along with Depression, Postpartum in 15 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Depression, Postpartum: Depression in POSTPARTUM WOMEN, usually within four weeks after giving birth (PARTURITION). The degree of depression ranges from mild transient depression to neurotic or psychotic depressive disorders. (From DSM-IV, p386)

Research Excerpts

ExcerptRelevanceReference
"PDS was determined by an Edinburgh Postnatal Depression Scale (EPDS) score ≥ 13."1.56The role of kynurenine pathway and kynurenic aminotransferase alleles in postpartum depression following cesarean section in Chinese women. ( Duan, K; Hu, N; Huang, Z; Long, G; Ma, J; Quan, C; Wang, S; Yang, M; Yu, H; Zeng, G, 2020)
"PDS was determined by an Edinburgh Postnatal Depression Scale (EPDS) score ≥ 13."1.51The IDO genetic polymorphisms and postpartum depressive symptoms: an association study in Chinese parturients who underwent cesarean section. ( Duan, KM; Huang, ZD; Li, X; Liu, ZQ; Ma, JH; Wang, SY; Yang, M; Yin, JY; Yu, HY; Zhou, HH; Zhou, YY, 2019)
"PPD was diagnosed with an Edinburgh Postnatal Depression Scale (EPDS) score ≥13."1.48[Correlation between kynurenine metabolites and postpartum depression]. ( Duan, K; Quan, C; Tan, Y; Wang, S; Wen, S; Zhang, J, 2018)
"PDS was determined by an Edinburgh Postnatal Depression Scale (EPDS) score ≥13."1.46Genetic variants of the kynurenine-3-monooxygenase and postpartum depressive symptoms after cesarean section in Chinese women. ( Duan, KM; Liu, ZQ; Mao, XY; Peng, C; Tan, XF; Wang, CY; Wang, SY; Yang, M; Yin, JY; Zheng, W; Zhou, HH, 2017)
"Kynurenine was significantly lower in patients with PP and PD as compared to healthy postpartum women (p=0."1.43Tryptophan pathway alterations in the postpartum period and in acute postpartum psychosis and depression. ( Bergink, V; Burgerhout, KM; Drexhage, HA; Hoogendijk, WJ; Kushner, SA; Myint, AM; Schütze, G; Schwarz, MJ; Veen, C, 2016)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.67)29.6817
2010's6 (40.00)24.3611
2020's8 (53.33)2.80

Authors

AuthorsStudies
Li, S1
Yang, Z1
Yao, M1
Shen, Y1
Zhu, H1
Jiang, Y1
Ji, Y1
Yin, J1
Levin, G1
Ein-Dor, T1
Achtyes, E3
Keaton, SA1
Smart, L2
Burmeister, AR1
Heilman, PL1
Krzyzanowski, S1
Nagalla, M2
Guillemin, GJ2
Escobar Galvis, ML1
Lim, CK1
Muzik, M1
Postolache, TT1
Leach, R2
Brundin, L3
Quan, C2
Wang, S2
Duan, K2
Ma, J1
Yu, H2
Yang, M3
Hu, N1
Long, G1
Zeng, G1
Huang, Z2
Badawy, AA1
Sha, Q1
Keaton, S1
Qiu, W1
Go, KA1
Lamers, Y1
Galea, LAM1
Wang, SY3
Duan, KM3
Tan, XF1
Yin, JY2
Mao, XY1
Zheng, W1
Wang, CY1
Peng, C1
Zhou, HH2
Liu, ZQ2
Roomruangwong, C1
Kanchanatawan, B1
Sirivichayakul, S1
Anderson, G1
Carvalho, AF1
Duleu, S1
Geffard, M1
Maes, M1
Ma, JH2
Zhou, Y1
Li, X1
Huang, ZD1
Zhou, YY1
Yu, HY1
Tan, Y1
Wen, S1
Zhang, J1
Veen, C1
Myint, AM1
Burgerhout, KM1
Schwarz, MJ1
Schütze, G1
Kushner, SA1
Hoogendijk, WJ1
Drexhage, HA1
Bergink, V1
Kohl, C1
Walch, T1
Huber, R1
Kemmler, G1
Neurauter, G1
Fuchs, D1
Sölder, E1
Schröcksnadel, H1
Sperner-Unterweger, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Genetic Risk Factors Predictive of the Occurrence of Maternally Diagnosed Perinatal Depression in Women[NCT05175755]3,000 participants (Anticipated)Interventional2023-09-25Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for kynurenine and Depression, Postpartum

ArticleYear
Exploration for biomarkers of postpartum depression based on metabolomics: A systematic review.
    Journal of affective disorders, 2022, 11-15, Volume: 317

    Topics: Biomarkers; Depression, Postpartum; Eicosapentaenoic Acid; Female; Humans; Kynurenic Acid; Kynurenin

2022
A unified model of the biology of peripartum depression.
    Translational psychiatry, 2023, 04-28, Volume: 13, Issue:1

    Topics: Biology; Depression; Depression, Postpartum; Depressive Disorder, Treatment-Resistant; Female; Human

2023
The role of tryptophan metabolism in postpartum depression.
    Metabolic brain disease, 2018, Volume: 33, Issue:3

    Topics: Depression; Depression, Postpartum; Depressive Disorder, Major; Female; Humans; Kynurenine; Quinolin

2018

Other Studies

12 other studies available for kynurenine and Depression, Postpartum

ArticleYear
Inflammation and kynurenine pathway dysregulation in post-partum women with severe and suicidal depression.
    Brain, behavior, and immunity, 2020, Volume: 83

    Topics: Adult; Cross-Sectional Studies; Depression, Postpartum; Female; Humans; Inflammation; Kynurenine; Po

2020
The role of kynurenine pathway and kynurenic aminotransferase alleles in postpartum depression following cesarean section in Chinese women.
    Brain and behavior, 2020, Volume: 10, Issue:4

    Topics: Adult; Alleles; Cesarean Section; Depression, Postpartum; Female; Genotype; Humans; Kynurenic Acid;

2020
Kynurenine pathway dysregulation in postpartum depression.
    Brain, behavior, and immunity, 2021, Volume: 91

    Topics: Depression, Postpartum; Female; Humans; Inflammation; Kynurenine; Postpartum Period; Suicidal Ideati

2021
Regarding letter on "Kynurenine pathway dysregulation in postpartum depression", by Achtyes et al, 2020.
    Brain, behavior, and immunity, 2021, Volume: 91

    Topics: Depression, Postpartum; Female; Humans; Inflammation; Kynurenine; Postpartum Period; Suicidal Ideati

2021
Associations between estrogen and progesterone, the kynurenine pathway, and inflammation in the post-partum.
    Journal of affective disorders, 2021, 02-15, Volume: 281

    Topics: Depression, Postpartum; Estrogens; Female; Humans; Inflammation; Kynurenine; Postpartum Period; Preg

2021
Postpartum corticosterone and fluoxetine shift the tryptophan-kynurenine pathway in dams.
    Psychoneuroendocrinology, 2021, Volume: 130

    Topics: Animals; Corticosterone; Depression, Postpartum; Depressive Disorder, Major; Female; Fluoxetine; Hum

2021
Genetic variants of the kynurenine-3-monooxygenase and postpartum depressive symptoms after cesarean section in Chinese women.
    Journal of affective disorders, 2017, Volume: 215

    Topics: Adult; Asian People; Case-Control Studies; Cesarean Section; China; Depression, Postpartum; Female;

2017
IgM-mediated autoimmune responses to oxidative specific epitopes, but not nitrosylated adducts, are significantly decreased in pregnancy: association with bacterial translocation, perinatal and lifetime major depression and the tryptophan catabolite (TRYC
    Metabolic brain disease, 2017, Volume: 32, Issue:5

    Topics: Adult; Autoimmunity; Bacterial Translocation; Biomarkers; Cytokines; Depression, Postpartum; Depress

2017
The IDO genetic polymorphisms and postpartum depressive symptoms: an association study in Chinese parturients who underwent cesarean section.
    Archives of women's mental health, 2019, Volume: 22, Issue:3

    Topics: Adult; Asian People; Case-Control Studies; Cesarean Section; China; Depression, Postpartum; Female;

2019
[Correlation between kynurenine metabolites and postpartum depression].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2018, Jul-28, Volume: 43, Issue:7

    Topics: Biomarkers; Cesarean Section; China; Depression, Postpartum; Female; Humans; Incidence; Kynurenic Ac

2018
Tryptophan pathway alterations in the postpartum period and in acute postpartum psychosis and depression.
    Journal of affective disorders, 2016, Jan-01, Volume: 189

    Topics: Adult; Depression, Postpartum; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine;

2016
Measurement of tryptophan, kynurenine and neopterin in women with and without postpartum blues.
    Journal of affective disorders, 2005, Volume: 86, Issue:2-3

    Topics: Adult; Austria; Depression, Postpartum; Female; Humans; Kynurenine; Labor, Obstetric; Neopterin; Pos

2005