kynurenine has been researched along with Debility in 7 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The kynurenine pathway is implicated in aging, longevity, and immune regulation, but longitudinal studies and assessment of the cerebrospinal fluid (CSF) are lacking." | 8.12 | Kynurenine Pathway Metabolites in the Blood and Cerebrospinal Fluid Are Associated with Human Aging. ( Cabral-Marques, O; Dugué, PA; Giil, LM; Giles, GG; Halaas, NB; Hodge, A; Idland, AV; McCann, A; Midttun, Ø; Nordrehaug, JE; Nygård, O; Solvang, SH; Tell, GS; Ueland, PM; Ulvik, A; Watne, LO, 2022) |
| "The kynurenine pathway is implicated in aging, longevity, and immune regulation, but longitudinal studies and assessment of the cerebrospinal fluid (CSF) are lacking." | 4.12 | Kynurenine Pathway Metabolites in the Blood and Cerebrospinal Fluid Are Associated with Human Aging. ( Cabral-Marques, O; Dugué, PA; Giil, LM; Giles, GG; Halaas, NB; Hodge, A; Idland, AV; McCann, A; Midttun, Ø; Nordrehaug, JE; Nygård, O; Solvang, SH; Tell, GS; Ueland, PM; Ulvik, A; Watne, LO, 2022) |
| "Kynurenine (Kyn) is a circulating tryptophan (Trp) catabolite generated by enzymes including IDO1 that are induced by inflammatory cytokines such as interferon-gamma." | 3.01 | The kynurenine pathway in HIV, frailty and inflammaging. ( Belin de Chantemèle, E; Bensreti, H; Elengickal, A; Hamrick, MW; McGee-Lawrence, ME; Sultana, S, 2023) |
| "Frailty is a progressive physiologic decline in multiple body systems, characterized by loss of function, loss of physiologic reserve, and increased vulnerability to disease and death." | 1.48 | Immunological alterations in frail older adults: A cross sectional study. ( Bonassi, S; Fuchs, D; Gostner, JM; Lorenzi, M; Marcos-Pérez, D; Onder, G; Strasser, B; Valdiglesias, V, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 6 (85.71) | 2.80 |
| Authors | Studies |
|---|---|
| Solvang, SH | 1 |
| Hodge, A | 1 |
| Watne, LO | 1 |
| Cabral-Marques, O | 1 |
| Nordrehaug, JE | 1 |
| Giles, GG | 1 |
| Dugué, PA | 1 |
| Nygård, O | 1 |
| Ueland, PM | 1 |
| McCann, A | 1 |
| Idland, AV | 1 |
| Midttun, Ø | 1 |
| Ulvik, A | 1 |
| Halaas, NB | 1 |
| Tell, GS | 1 |
| Giil, LM | 1 |
| Chung, T | 1 |
| Bopp, T | 1 |
| Ward, C | 1 |
| Notarangelo, FM | 1 |
| Schwarcz, R | 1 |
| Westbrook, R | 1 |
| Xue, QL | 1 |
| Walston, J | 1 |
| Hoke, A | 1 |
| Ballesteros, J | 1 |
| Rivas, D | 1 |
| Duque, G | 1 |
| Sultana, S | 1 |
| Elengickal, A | 1 |
| Bensreti, H | 1 |
| Belin de Chantemèle, E | 1 |
| McGee-Lawrence, ME | 1 |
| Hamrick, MW | 2 |
| Kim, BJ | 2 |
| Lee, SH | 1 |
| Koh, JM | 1 |
| Jang, IY | 1 |
| Park, JH | 1 |
| Kim, JH | 1 |
| Lee, S | 1 |
| Lee, E | 1 |
| Lee, JY | 1 |
| Park, SJ | 1 |
| Kim, DA | 1 |
| Valdiglesias, V | 1 |
| Marcos-Pérez, D | 1 |
| Lorenzi, M | 1 |
| Onder, G | 1 |
| Gostner, JM | 1 |
| Strasser, B | 1 |
| Fuchs, D | 1 |
| Bonassi, S | 1 |
3 reviews available for kynurenine and Debility
| Article | Year |
|---|---|
The Role of the Kynurenine Pathway in the Pathophysiology of Frailty, Sarcopenia, and Osteoporosis.
Topics: Aged; Aged, 80 and over; Frailty; Humans; Kynurenine; Osteoporosis; Sarcopenia; Tryptophan | 2023 |
The kynurenine pathway in HIV, frailty and inflammaging.
Topics: Aged; Cytokines; Frailty; HIV Infections; Humans; Kynurenine; Tryptophan | 2023 |
Clinical insights into the kynurenine pathway in age-related diseases.
Topics: Aged; Aging; Animals; Biomarkers; Frailty; Humans; Kynurenine; Metabolic Networks and Pathways; Tryp | 2020 |
4 other studies available for kynurenine and Debility
| Article | Year |
|---|---|
Kynurenine Pathway Metabolites in the Blood and Cerebrospinal Fluid Are Associated with Human Aging.
Topics: Aged; Aging; Child, Preschool; Frailty; Humans; Kynurenine; Quinolinic Acid; Tryptophan | 2022 |
Deletion of quinolinate phosphoribosyltransferase gene accelerates frailty phenotypes and neuromuscular decline with aging in a sex-specific pattern.
Topics: Aging; Animals; Female; Frailty; Kynurenine; Male; Mice; Muscle Weakness; Phenotype | 2023 |
The association of circulating kynurenine, a tryptophan metabolite, with frailty in older adults.
Topics: Age Factors; Aged; Biomarkers; Chromatography, Liquid; Cross-Sectional Studies; Female; Frail Elderl | 2020 |
Immunological alterations in frail older adults: A cross sectional study.
Topics: Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; Cross-Sectional Studies; Female; Frail Elde | 2018 |