kynurenine has been researched along with Coronary Heart Disease in 5 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In plasma from 3035 patients undergoing coronary angiography for suspected coronary heart disease, we investigated if plasma concentrations of any metabolites in the kynurenine pathway, which depend on PLP as cofactor, may serve as metabolic marker(s) of vitamin B-6 status." | 7.77 | Low plasma vitamin B-6 status affects metabolism through the kynurenine pathway in cardiovascular patients with systemic inflammation. ( Bleie, O; Ebbing, M; Midttun, O; Nilsen, RM; Nygård, O; Ringdal Pedersen, E; Schartum-Hansen, H; Ueland, PM; Ulvik, A, 2011) |
| "Blood concentrations of kynurenine and free tryptophan and the kynurenine to tryptophan ratio were examined in 35 patients with coronary heart disease verified by coronary angiography and compared with healthy controls." | 7.72 | Immune activation and degradation of tryptophan in coronary heart disease. ( Erglis, A; Fuchs, D; Kalnins, U; Murr, C; Neurauter, G; Rudzite, V; Trusinskis, K; Wirleitner, B, 2003) |
| " In plasma from 3035 patients undergoing coronary angiography for suspected coronary heart disease, we investigated if plasma concentrations of any metabolites in the kynurenine pathway, which depend on PLP as cofactor, may serve as metabolic marker(s) of vitamin B-6 status." | 3.77 | Low plasma vitamin B-6 status affects metabolism through the kynurenine pathway in cardiovascular patients with systemic inflammation. ( Bleie, O; Ebbing, M; Midttun, O; Nilsen, RM; Nygård, O; Ringdal Pedersen, E; Schartum-Hansen, H; Ueland, PM; Ulvik, A, 2011) |
| "Blood concentrations of kynurenine and free tryptophan and the kynurenine to tryptophan ratio were examined in 35 patients with coronary heart disease verified by coronary angiography and compared with healthy controls." | 3.72 | Immune activation and degradation of tryptophan in coronary heart disease. ( Erglis, A; Fuchs, D; Kalnins, U; Murr, C; Neurauter, G; Rudzite, V; Trusinskis, K; Wirleitner, B, 2003) |
| "Tryptophan load test followed by serum kynurenine determination at fasting state and after L-tryptophan loading, as well as serum pyridoxal-5-phosphate (P-5-P), homocysteine and neopterin concentrations at fasting state have been examined in 30 healthy individuals and 87 patients with coronary heart disease (CHD), verified by coronary angiography." | 3.72 | Prognostic value of tryptophan load test followed by serum kynurenine determination. Its comparison with pyridoxal-5-phosphate, kynurenine, homocysteine and neopterin amounts. ( Erglis, A; Fuchs, D; Jegere, S; Jurika, E; Kalnins, U; Rudzite, V; Silava, A; Trusinskis, K, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Midttun, O | 1 |
| Ulvik, A | 1 |
| Ringdal Pedersen, E | 1 |
| Ebbing, M | 1 |
| Bleie, O | 1 |
| Schartum-Hansen, H | 1 |
| Nilsen, RM | 1 |
| Nygård, O | 1 |
| Ueland, PM | 1 |
| Wirleitner, B | 1 |
| Rudzite, V | 3 |
| Neurauter, G | 1 |
| Murr, C | 1 |
| Kalnins, U | 2 |
| Erglis, A | 2 |
| Trusinskis, K | 2 |
| Fuchs, D | 2 |
| Jurika, E | 2 |
| Silava, A | 1 |
| Jegere, S | 1 |
| Rudzit, VK | 1 |
| Silenietse, GO | 1 |
| Zirne, RA | 1 |
| Iurika, EV | 1 |
| Jirgensons, J | 1 |
| Sileniece, G | 1 |
| Zirne, R | 1 |
| Jirgensone, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomised Double Blind Study of the Effects of Homocysteine Lowering Therapy on Mortality and Cardiac Events in Patients Undergoing Coronary Angiography[NCT00354081] | Phase 3 | 3,096 participants (Actual) | Interventional | 1999-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for kynurenine and Coronary Heart Disease
| Article | Year |
|---|---|
Low plasma vitamin B-6 status affects metabolism through the kynurenine pathway in cardiovascular patients with systemic inflammation.
Topics: Adult; Aged; C-Reactive Protein; Coronary Disease; Female; Humans; Inflammation; Kynurenine; Male; M | 2011 |
Immune activation and degradation of tryptophan in coronary heart disease.
Topics: Aged; Coronary Disease; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Midd | 2003 |
Prognostic value of tryptophan load test followed by serum kynurenine determination. Its comparison with pyridoxal-5-phosphate, kynurenine, homocysteine and neopterin amounts.
Topics: Biomarkers; Case-Control Studies; Coronary Disease; Homocysteine; Humans; Kynurenine; Neopterin; Pro | 2003 |
[Kynureninemia in patients with hypertension and ischemic heart disease previously treated with antitubercular drugs].
Topics: Antitubercular Agents; Coronary Disease; Humans; Hypertension; Kynurenine; Tuberculosis, Pulmonary | 1988 |
[Peculiarities of nicotinic acid formation in coronary heart disease with special reference to heart arrhythmias].
Topics: Angina Pectoris; Animals; Arrhythmias, Cardiac; Coronary Disease; Female; Humans; Kynurenine; Lipid | 1988 |