kynurenine has been researched along with Complications, Pregnancy in 7 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We hypothesize that: (1) L-tryptophan (Trp) is greatly utilized and not depleted in pregnancy; (2) fetal tolerance is achieved in part through immunosuppressive kynurenine (Kyn) metabolites produced by the flux of plasma free (non-albumin-bound) Trp down the Kyn pathway; (3) the role of indoleamine 2,3-dioxygenase (IDO) in infection is not related to limitation of an essential amino acid, but is rather associated with stress responses and the production of Kyn metabolites that regulate the activities of antigen presenting cells and T-cells, as well as increased NAD(+) synthesis in IDO-expressing cells; (4) Trp depletion is not a host defence mechanism, but is a consequence of Trp utilization." | 8.93 | The end of the road for the tryptophan depletion concept in pregnancy and infection. ( Badawy, AA; Moffett, JR; Namboodiri, AM, 2016) |
| " The present study examined the diagnostic ability of tryptophan catabolites (TRYCATs) and insulin resistance (IR) parameters in women with PE." | 8.31 | Maternal Tryptophan Catabolites and Insulin Resistance Parameters in Preeclampsia. ( Al-Hakeim, HK; Jasim, ZA; Stanek, A; Zolghadri, S, 2023) |
| "Higher estimated tryptophan intake was cross-sectionally independently associated with a lower prevalence of depressive symptoms during pregnancy in Japanese women." | 8.12 | Tryptophan intake is related to a lower prevalence of depressive symptoms during pregnancy in Japan: baseline data from the Kyushu Okinawa Maternal and Child Health Study. ( Arakawa, M; Miyake, Y; Okubo, H; Sasaki, S; Tanaka, K, 2022) |
| "To evaluate relationships among obesity in pregnancy and plasma levels of tryptophan (TRP) and kynurenine (KYN), inflammatory markers, and depressed mood." | 7.88 | Associations Among Obesity, Inflammation, and Tryptophan Catabolism in Pregnancy. ( D'Agata, A; Duffy, A; Fuchs, D; Groer, M; Louis-Jacques, A; Postolache, TT, 2018) |
| "We hypothesize that: (1) L-tryptophan (Trp) is greatly utilized and not depleted in pregnancy; (2) fetal tolerance is achieved in part through immunosuppressive kynurenine (Kyn) metabolites produced by the flux of plasma free (non-albumin-bound) Trp down the Kyn pathway; (3) the role of indoleamine 2,3-dioxygenase (IDO) in infection is not related to limitation of an essential amino acid, but is rather associated with stress responses and the production of Kyn metabolites that regulate the activities of antigen presenting cells and T-cells, as well as increased NAD(+) synthesis in IDO-expressing cells; (4) Trp depletion is not a host defence mechanism, but is a consequence of Trp utilization." | 4.93 | The end of the road for the tryptophan depletion concept in pregnancy and infection. ( Badawy, AA; Moffett, JR; Namboodiri, AM, 2016) |
| " The present study examined the diagnostic ability of tryptophan catabolites (TRYCATs) and insulin resistance (IR) parameters in women with PE." | 4.31 | Maternal Tryptophan Catabolites and Insulin Resistance Parameters in Preeclampsia. ( Al-Hakeim, HK; Jasim, ZA; Stanek, A; Zolghadri, S, 2023) |
| "Higher estimated tryptophan intake was cross-sectionally independently associated with a lower prevalence of depressive symptoms during pregnancy in Japanese women." | 4.12 | Tryptophan intake is related to a lower prevalence of depressive symptoms during pregnancy in Japan: baseline data from the Kyushu Okinawa Maternal and Child Health Study. ( Arakawa, M; Miyake, Y; Okubo, H; Sasaki, S; Tanaka, K, 2022) |
| "To evaluate relationships among obesity in pregnancy and plasma levels of tryptophan (TRP) and kynurenine (KYN), inflammatory markers, and depressed mood." | 3.88 | Associations Among Obesity, Inflammation, and Tryptophan Catabolism in Pregnancy. ( D'Agata, A; Duffy, A; Fuchs, D; Groer, M; Louis-Jacques, A; Postolache, TT, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Miyake, Y | 1 |
| Tanaka, K | 1 |
| Okubo, H | 1 |
| Sasaki, S | 1 |
| Arakawa, M | 1 |
| Jasim, ZA | 1 |
| Al-Hakeim, HK | 1 |
| Zolghadri, S | 1 |
| Stanek, A | 1 |
| Groer, M | 1 |
| Fuchs, D | 1 |
| Duffy, A | 1 |
| Louis-Jacques, A | 1 |
| D'Agata, A | 1 |
| Postolache, TT | 1 |
| Murthi, P | 1 |
| Vaillancourt, C | 1 |
| Badawy, AA | 1 |
| Namboodiri, AM | 1 |
| Moffett, JR | 1 |
| Oades, RD | 1 |
| Gorbacheva, LN | 1 |
2 reviews available for kynurenine and Complications, Pregnancy
| Article | Year |
|---|---|
RETRACTED: Placental serotonin systems in pregnancy metabolic complications associated with maternal obesity and gestational diabetes mellitus.
Topics: Diabetes, Gestational; Embryonic Development; Female; Fetal Development; Homeostasis; Humans; Inflam | 2020 |
The end of the road for the tryptophan depletion concept in pregnancy and infection.
Topics: Antigen-Presenting Cells; Communicable Diseases; Female; Fetus; Humans; Immune Tolerance; Indoleamin | 2016 |
5 other studies available for kynurenine and Complications, Pregnancy
| Article | Year |
|---|---|
Tryptophan intake is related to a lower prevalence of depressive symptoms during pregnancy in Japan: baseline data from the Kyushu Okinawa Maternal and Child Health Study.
Topics: Calcium; Child; Child Health; Cross-Sectional Studies; Depression; Docosahexaenoic Acids; Eicosapent | 2022 |
Maternal Tryptophan Catabolites and Insulin Resistance Parameters in Preeclampsia.
Topics: Case-Control Studies; Female; Humans; Insulin Resistance; Kynurenic Acid; Kynurenine; Pre-Eclampsia; | 2023 |
Associations Among Obesity, Inflammation, and Tryptophan Catabolism in Pregnancy.
Topics: Adult; Biomarkers; Body Mass Index; Cross-Sectional Studies; Female; Humans; Indoleamine-Pyrrole 2,3 | 2018 |
An exploration of the associations of pregnancy and perinatal features with cytokines and tryptophan/kynurenine metabolism in children with attention-deficit hyperactivity disorder (ADHD).
Topics: Adult; Alcohol Drinking; Attention Deficit Disorder with Hyperactivity; Case-Control Studies; Child; | 2011 |
[Tryptophan metabolism via the kynurenine and serotonin pathways in pregnancy nephropathy].
Topics: Female; Humans; Kidney Diseases; Kynurenine; Postpartum Period; Pre-Eclampsia; Pregnancy; Pregnancy | 1978 |