kynurenine has been researched along with Colorectal Cancer in 10 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " pylori seronegative and seropositive colorectal cancer patients, while serum tryptophan levels were decreased (controls vs patients; seronegative: 20." | 7.81 | Helicobacter pylori and serum kynurenine-tryptophan ratio in patients with colorectal cancer. ( Engin, A; Engin, AB; Karahalil, B; Karakaya, AE, 2015) |
| "We tested the hypothesis that reduced tryptophan availability due to immunological stimulation in colorectal cancer impairs quality of life (QoL) by measuring serum tryptophan levels, and correlating them with serum immunological markers and with QoL indices." | 7.72 | Tryptophan and quality of life in colorectal cancer. ( Allen-Mersh, TG; Fuchs, D; Glover, C; Henderson, DC; Huang, A; Widner, B, 2003) |
| "Serotonin system also increases colorectal cancer cells proliferation and metastasis while, indole metabolites can profoundly decrease colorectal cancer growth." | 6.82 | Tryptophan metabolites modulate inflammatory bowel disease and colorectal cancer by affecting immune system. ( Ala, M, 2022) |
| "Sixty-six patients with colorectal cancer were studied (39 males; median age 66 years) of whom 25 had colorectal liver metastases only (17 males; median age 62 years; median liver metastasis volume 208 ml; median survival 234 days)." | 5.31 | Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer. ( Allen-Mersh, TG; Fuchs, D; Glover, C; Henderson, DC; Huang, A; Widner, B, 2002) |
| " pylori seronegative and seropositive colorectal cancer patients, while serum tryptophan levels were decreased (controls vs patients; seronegative: 20." | 3.81 | Helicobacter pylori and serum kynurenine-tryptophan ratio in patients with colorectal cancer. ( Engin, A; Engin, AB; Karahalil, B; Karakaya, AE, 2015) |
| "We tested the hypothesis that reduced tryptophan availability due to immunological stimulation in colorectal cancer impairs quality of life (QoL) by measuring serum tryptophan levels, and correlating them with serum immunological markers and with QoL indices." | 3.72 | Tryptophan and quality of life in colorectal cancer. ( Allen-Mersh, TG; Fuchs, D; Glover, C; Henderson, DC; Huang, A; Widner, B, 2003) |
| "Serotonin system also increases colorectal cancer cells proliferation and metastasis while, indole metabolites can profoundly decrease colorectal cancer growth." | 2.82 | Tryptophan metabolites modulate inflammatory bowel disease and colorectal cancer by affecting immune system. ( Ala, M, 2022) |
| "We used human and mouse colorectal cancer cell lines, organoids, mouse syngeneic colorectal cancer tumor graft models, and colorectal cancer tissues from patients who received radiotherapy." | 1.56 | Interferon-Induced IDO1 Mediates Radiation Resistance and Is a Therapeutic Target in Colorectal Cancer. ( Alvarado, DM; Chen, B; Ciorba, MA; Iticovici, M; Kau, NS; Parikh, PJ; Park, H; Thotala, D, 2020) |
| "To improve the quality of life of colorectal cancer patients, it is important to establish new screening methods for early diagnosis of colorectal cancer." | 1.38 | A novel serum metabolomics-based diagnostic approach for colorectal cancer. ( Azuma, T; Hayashi, N; Ikeda, A; Izumi, Y; Kawano, S; Kibi, M; Kobayashi, T; Nishiumi, S; Okuno, T; Takenawa, T; Yoshida, M; Yoshie, T, 2012) |
| "Sixty-six patients with colorectal cancer were studied (39 males; median age 66 years) of whom 25 had colorectal liver metastases only (17 males; median age 62 years; median liver metastasis volume 208 ml; median survival 234 days)." | 1.31 | Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer. ( Allen-Mersh, TG; Fuchs, D; Glover, C; Henderson, DC; Huang, A; Widner, B, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zor, DS | 1 |
| Hakan, MT | 1 |
| Özgür, E | 1 |
| Horozoglu, C | 1 |
| Yörüker, EE | 1 |
| Kulle, CB | 1 |
| Gezer, U | 1 |
| Yaylim, I | 1 |
| Chen, B | 2 |
| Alvarado, DM | 2 |
| Iticovici, M | 1 |
| Kau, NS | 1 |
| Park, H | 1 |
| Parikh, PJ | 1 |
| Thotala, D | 1 |
| Ciorba, MA | 2 |
| Ala, M | 1 |
| Bishnupuri, KS | 1 |
| Khouri, AN | 1 |
| Shabsovich, M | 1 |
| Dieckgraefe, BK | 1 |
| Engin, AB | 2 |
| Karahalil, B | 1 |
| Karakaya, AE | 1 |
| Engin, A | 2 |
| Gonul, II | 1 |
| Karamercan, A | 1 |
| Sepici Dincel, A | 1 |
| Dursun, A | 1 |
| Gylling, B | 1 |
| Myte, R | 1 |
| Schneede, J | 1 |
| Hallmans, G | 1 |
| Häggström, J | 1 |
| Johansson, I | 1 |
| Ulvik, A | 1 |
| Ueland, PM | 1 |
| Van Guelpen, B | 1 |
| Palmqvist, R | 1 |
| Nishiumi, S | 1 |
| Kobayashi, T | 1 |
| Ikeda, A | 1 |
| Yoshie, T | 1 |
| Kibi, M | 1 |
| Izumi, Y | 1 |
| Okuno, T | 1 |
| Hayashi, N | 1 |
| Kawano, S | 1 |
| Takenawa, T | 1 |
| Azuma, T | 1 |
| Yoshida, M | 1 |
| Huang, A | 2 |
| Fuchs, D | 2 |
| Widner, B | 2 |
| Glover, C | 2 |
| Henderson, DC | 2 |
| Allen-Mersh, TG | 2 |
1 review available for kynurenine and Colorectal Cancer
| Article | Year |
|---|---|
Tryptophan metabolites modulate inflammatory bowel disease and colorectal cancer by affecting immune system.
Topics: Colitis; Colorectal Neoplasms; Humans; Indoles; Inflammatory Bowel Diseases; Kynurenine; Serotonin; | 2022 |
9 other studies available for kynurenine and Colorectal Cancer
| Article | Year |
|---|---|
Plasma Levels of Kynurenine, Soluble OX40 and Mir-138-5p Are Associated With Tumor-infiltrating Lymphocytes in Colorectal Cancer: An Exploratory Study.
Topics: B7-H1 Antigen; Colorectal Neoplasms; Humans; Kynurenine; Lymphocytes; MicroRNAs; Tryptophan; Tumor M | 2023 |
Interferon-Induced IDO1 Mediates Radiation Resistance and Is a Therapeutic Target in Colorectal Cancer.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Colorectal Neoplasms; Female; Gene Expression Regu | 2020 |
IDO1 and Kynurenine Pathway Metabolites Activate PI3K-Akt Signaling in the Neoplastic Colon Epithelium to Promote Cancer Cell Proliferation and Inhibit Apoptosis.
Topics: Animals; Apoptosis; Biomarkers, Tumor; Cell Proliferation; Colon; Colonic Neoplasms; Colorectal Neop | 2019 |
Helicobacter pylori and serum kynurenine-tryptophan ratio in patients with colorectal cancer.
Topics: Antibodies, Bacterial; Biomarkers, Tumor; Case-Control Studies; Chromatography, High Pressure Liquid | 2015 |
Relationship between indoleamine 2,3-dioxygenase activity and lymphatic invasion propensity of colorectal carcinoma.
Topics: Biomarkers, Tumor; Biopterins; Carcinoma; Case-Control Studies; Chromatography, High Pressure Liquid | 2016 |
Vitamin B-6 and colorectal cancer risk: a prospective population-based study using 3 distinct plasma markers of vitamin B-6 status.
Topics: Adult; Aged; Biomarkers; Case-Control Studies; Colorectal Neoplasms; Female; Humans; Inflammation; K | 2017 |
A novel serum metabolomics-based diagnostic approach for colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Area Under Curve; Aspartic Acid; Biomarkers, Tumor; Case-Control Stu | 2012 |
Tryptophan and quality of life in colorectal cancer.
Topics: Case-Control Studies; Colorectal Neoplasms; Humans; Kynurenine; Quality of Life; Th1 Cells; Tryptoph | 2003 |
Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer.
Topics: Adenocarcinoma; Aged; Colonic Neoplasms; Colorectal Neoplasms; Humans; Interleukin-6; Kynurenine; Li | 2002 |