kynurenine has been researched along with Colitis Gravis in 9 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Inflammation induces tryptophan metabolism along the kynurenine pathway (KP) and yields immunologically relevant metabolites." | 7.88 | Tryptophan Metabolism through the Kynurenine Pathway is Associated with Endoscopic Inflammation in Ulcerative Colitis. ( Bissonnette, M; Ciorba, MA; Guillemin, GJ; Lim, CK; Meckel, K; Pekow, JR; Sofia, MA; Weber, CR, 2018) |
| " Inflammation induces tryptophan metabolism along the kynurenine pathway (KP) and yields immunologically relevant metabolites." | 3.88 | Tryptophan Metabolism through the Kynurenine Pathway is Associated with Endoscopic Inflammation in Ulcerative Colitis. ( Bissonnette, M; Ciorba, MA; Guillemin, GJ; Lim, CK; Meckel, K; Pekow, JR; Sofia, MA; Weber, CR, 2018) |
| "C57Bl6 wild-type (control), IDO1-/-, Rag1-/-, and Rag1/IDO1 double-knockout mice were exposed to azoxymethane and dextran sodium sulfate to induce colitis and tumorigenesis." | 3.79 | IDO1 metabolites activate β-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice. ( Bishnupuri, KS; Ciorba, MA; Foster, L; Kerr, TA; Marinshaw, JM; Newberry, RD; Rao, MS; Stenson, WF; Thaker, AI, 2013) |
| "Crohn's disease (CD) and ulcerative colitis (UC) are inflammatory bowel diseases (IBD) characterized by variable phenotypes." | 1.40 | Bimodal plasma metabolomics strategy identifies novel inflammatory metabolites in inflammatory bowel diseases. ( Bustamante, S; Campbell, B; Hejazi, L; Leong, RW; Pickford, R; Shin, S; Wasinger, VC; Yau, YY, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 3 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Lai, W | 1 |
| Huang, Z | 1 |
| Li, S | 2 |
| Li, XG | 1 |
| Luo, D | 1 |
| Karpińska, G | 1 |
| Dobrowolski, JC | 1 |
| Yinda, CK | 1 |
| Rector, A | 1 |
| Zeller, M | 1 |
| Conceição-Neto, N | 1 |
| Heylen, E | 1 |
| Maes, P | 1 |
| Ghogomu, SM | 1 |
| Van Ranst, M | 1 |
| Matthijnssens, J | 1 |
| Arthanari, SK | 1 |
| Vanitha, J | 1 |
| Ganesh, M | 1 |
| Venkateshwaran, K | 1 |
| de Lama Caro-Patón, G | 1 |
| García-Salido, A | 1 |
| Iglesias-Bouzas, MI | 1 |
| Guillén, M | 1 |
| Cañedo-Villaroya, E | 1 |
| Martínez-Romera, I | 1 |
| Serrano-González, A | 1 |
| Casado-Flores, J | 1 |
| Gale, P | 2 |
| Chen, X | 2 |
| Li, H | 1 |
| Lucero-Prisno, DE | 1 |
| Abdullah, AS | 1 |
| Huang, J | 1 |
| Laurence, C | 1 |
| Liang, X | 1 |
| Ma, Z | 1 |
| Mao, Z | 1 |
| Ren, R | 1 |
| Wu, S | 1 |
| Wang, N | 1 |
| Wang, P | 2 |
| Wang, T | 1 |
| Yan, H | 1 |
| Zou, Y | 1 |
| Olsen, KM | 1 |
| Gabler, NK | 1 |
| Rademacher, CJ | 1 |
| Schwartz, KJ | 1 |
| Schweer, WP | 1 |
| Gourley, GG | 1 |
| Patience, JF | 1 |
| Rauch, JC | 1 |
| Stokes, RS | 1 |
| Shike, DW | 1 |
| Luebbe, KM | 1 |
| Stalker, LA | 1 |
| Klopfenstein, TJ | 1 |
| Funston, RN | 1 |
| Unger, PA | 1 |
| Lighaam, LC | 1 |
| Vermeulen, E | 1 |
| Kruithof, S | 1 |
| Makuch, M | 1 |
| Culver, EL | 1 |
| van Bruggen, R | 1 |
| Remmerswaal, EBM | 1 |
| Ten Berge, IJM | 1 |
| Emmens, RW | 1 |
| Niessen, HWM | 1 |
| Barnes, E | 1 |
| Wolbink, GJ | 1 |
| van Ham, SM | 1 |
| Rispens, T | 1 |
| Liang, JX | 1 |
| Lin, J | 1 |
| Liu, J | 1 |
| Wang, X | 1 |
| Zhang, T | 1 |
| Li, J | 1 |
| Wu, Y | 2 |
| Venier, M | 1 |
| Salamova, A | 1 |
| Gonçales, VR | 1 |
| Lian, J | 1 |
| Gautam, S | 1 |
| Tilley, RD | 1 |
| Gooding, JJ | 1 |
| Kandel, YR | 1 |
| Bradley, CA | 1 |
| Chilvers, MI | 1 |
| Mathew, FM | 1 |
| Tenuta, AU | 1 |
| Smith, DL | 1 |
| Wise, KA | 1 |
| Mueller, DS | 1 |
| Lu, N | 1 |
| Lu, M | 1 |
| Liu, P | 1 |
| Xu, H | 1 |
| Qiu, X | 1 |
| Hu, S | 1 |
| Bai, S | 1 |
| Wu, J | 1 |
| Xue, S | 1 |
| Dai, X | 1 |
| Dharmage, SC | 1 |
| Abramson, MJ | 1 |
| Erbas, B | 1 |
| Bennett, CM | 1 |
| Svanes, C | 1 |
| Hui, J | 1 |
| Axelrad, C | 1 |
| Lowe, AJ | 1 |
| Lodge, CJ | 1 |
| Hoshi, M | 1 |
| Osawa, Y | 1 |
| Nakamoto, K | 1 |
| Morita, N | 1 |
| Yamamoto, Y | 1 |
| Ando, T | 1 |
| Tashita, C | 1 |
| Nabeshima, T | 1 |
| Saito, K | 1 |
| Gianesello, L | 1 |
| Del Prete, D | 1 |
| Ceol, M | 1 |
| Priante, G | 1 |
| Calò, LA | 1 |
| Anglani, F | 1 |
| Vekaria, HJ | 1 |
| Hubbard, WB | 1 |
| Scholpa, NE | 1 |
| Spry, ML | 1 |
| Gooch, JL | 1 |
| Prince, SJ | 1 |
| Schnellmann, RG | 1 |
| Sullivan, PG | 1 |
| Zhang, Q | 1 |
| Hu, R | 1 |
| Gu, Z | 1 |
| Zhang, M | 1 |
| Zhang, Z | 1 |
| Peng, Y | 1 |
| Feng, L | 1 |
| Li, X | 4 |
| Zhao, C | 1 |
| Sarfaraz, K | 1 |
| Gao, L | 1 |
| Wang, H | 1 |
| Wan, C | 1 |
| Leng, J | 1 |
| Yang, P | 1 |
| Gao, X | 1 |
| Gao, J | 1 |
| Emam, HE | 1 |
| Saad, NM | 1 |
| Abdallah, AEM | 1 |
| Ahmed, HB | 1 |
| Palombo, M | 1 |
| Ianus, A | 1 |
| Guerreri, M | 1 |
| Nunes, D | 1 |
| Alexander, DC | 1 |
| Shemesh, N | 1 |
| Zhang, H | 1 |
| Xiong, Q | 1 |
| Liu, YS | 1 |
| Hu, LX | 1 |
| Shi, ZQ | 1 |
| Ying, GG | 1 |
| Chen, R | 1 |
| Hong, X | 1 |
| Yan, S | 1 |
| Zha, J | 1 |
| Gu, H | 1 |
| Zhong, Q | 1 |
| Zeng, Y | 1 |
| Zhang, S | 1 |
| Bu, Y | 1 |
| Farghali, M | 1 |
| Mayumi, M | 1 |
| Syo, K | 1 |
| Satoshi, A | 1 |
| Seiichi, Y | 1 |
| Takashima, S | 1 |
| Ono, H | 1 |
| Ap, Y | 1 |
| Yamashiro, T | 1 |
| Ahmed, MM | 1 |
| Kotb, S | 1 |
| Iwasaki, M | 1 |
| Ihara, I | 1 |
| Umetsu, K | 1 |
| Hu, B | 1 |
| Wang, Y | 2 |
| Quan, J | 1 |
| Huang, K | 1 |
| Gu, X | 1 |
| Zhu, J | 1 |
| Yan, Y | 1 |
| Wu, P | 1 |
| Yang, L | 1 |
| Zhao, J | 1 |
| Koók, L | 1 |
| Nemestóthy, N | 1 |
| Bélafi-Bakó, K | 1 |
| Bakonyi, P | 1 |
| Luo, X | 1 |
| Zhang, F | 1 |
| Li, Q | 1 |
| Xia, Q | 1 |
| Li, Z | 1 |
| Ye, W | 1 |
| Ge, C | 1 |
| Zakkula, A | 1 |
| Pulipati, S | 1 |
| Dittakavi, S | 1 |
| Bestha, RM | 1 |
| Zainuddin, M | 1 |
| Trivedi, RK | 1 |
| Mullangi, R | 1 |
| Lo, GH | 1 |
| Lin, CW | 1 |
| Tai, CM | 1 |
| Perng, DS | 1 |
| Chen, IL | 1 |
| Yeh, JH | 1 |
| Lin, HC | 1 |
| Rocha, GS | 1 |
| Silva, MKL | 1 |
| Cesarino, I | 1 |
| Hazzaa, SM | 1 |
| Abdelaziz, SAM | 1 |
| Abd Eldaim, MA | 1 |
| Abdel-Daim, MM | 1 |
| Elgarawany, GE | 1 |
| Larsson, P | 1 |
| Ljuslinder, I | 1 |
| Öhlund, D | 1 |
| Myte, R | 1 |
| Löfgren-Burström, A | 1 |
| Zingmark, C | 1 |
| Ling, A | 1 |
| Edin, S | 1 |
| Palmqvist, R | 1 |
| Murthi, P | 1 |
| Rajaraman, G | 1 |
| Erwich, JJHM | 1 |
| Dimitriadis, E | 1 |
| Yoon, HG | 1 |
| Oh, D | 1 |
| Ahn, YC | 1 |
| Noh, JM | 1 |
| Pyo, H | 1 |
| Cho, WK | 1 |
| Song, YM | 1 |
| Park, M | 1 |
| Hwang, NY | 1 |
| Sun, JM | 1 |
| Kim, HK | 1 |
| Zo, JI | 1 |
| Shim, YM | 1 |
| Persano, A | 1 |
| Quaranta, F | 1 |
| Taurino, A | 1 |
| Siciliano, PA | 1 |
| Iannacci, J | 1 |
| Malekbala, MR | 1 |
| Soltani, S | 1 |
| Abdul Rashid, S | 1 |
| Abdullah, LC | 1 |
| Rashid, U | 1 |
| Nehdi, IA | 1 |
| Choong, TSY | 1 |
| Teo, SH | 1 |
| Xu, P | 1 |
| Yan, F | 1 |
| Zhao, Y | 1 |
| Sun, S | 1 |
| Ying, L | 1 |
| Quinzi, V | 1 |
| Caruso, S | 1 |
| Mummolo, S | 1 |
| Nota, A | 1 |
| Angelone, AM | 1 |
| Mattei, A | 1 |
| Gatto, R | 1 |
| Marzo, G | 1 |
| Xin, W | 1 |
| Severino, J | 1 |
| Venkert, A | 1 |
| Yu, H | 1 |
| Knorr, D | 1 |
| Yang, JM | 1 |
| Carlson, L | 1 |
| Hicks, R | 1 |
| De Rosa, I | 1 |
| Beckmann, NA | 1 |
| Bitsch, RG | 1 |
| Schonhoff, M | 1 |
| Siebenrock, KA | 1 |
| Schwarze, M | 1 |
| Jaeger, S | 1 |
| Manzella, CR | 1 |
| Jayawardena, D | 1 |
| Pagani, W | 1 |
| Li, Y | 1 |
| Alrefai, WA | 1 |
| Bauer, J | 1 |
| Jung, B | 1 |
| Weber, CR | 2 |
| Gill, RK | 1 |
| Zhang, ZH | 1 |
| Zabed, HM | 1 |
| Yun, J | 1 |
| Zhang, G | 1 |
| Qi, X | 1 |
| Sofia, MA | 1 |
| Ciorba, MA | 2 |
| Meckel, K | 1 |
| Lim, CK | 1 |
| Guillemin, GJ | 1 |
| Bissonnette, M | 1 |
| Pekow, JR | 1 |
| Whiley, L | 1 |
| Nye, LC | 1 |
| Grant, I | 1 |
| Andreas, N | 1 |
| Chappell, KE | 1 |
| Sarafian, MH | 1 |
| Misra, R | 1 |
| Plumb, RS | 1 |
| Lewis, MR | 1 |
| Nicholson, JK | 1 |
| Holmes, E | 1 |
| Swann, JR | 1 |
| Wilson, ID | 1 |
| Thaker, AI | 1 |
| Rao, MS | 1 |
| Bishnupuri, KS | 1 |
| Kerr, TA | 1 |
| Foster, L | 1 |
| Marinshaw, JM | 1 |
| Newberry, RD | 1 |
| Stenson, WF | 1 |
| Yau, YY | 1 |
| Leong, RW | 1 |
| Shin, S | 1 |
| Bustamante, S | 1 |
| Pickford, R | 1 |
| Hejazi, L | 1 |
| Campbell, B | 1 |
| Wasinger, VC | 1 |
| Forrest, CM | 1 |
| Gould, SR | 1 |
| Darlington, LG | 1 |
| Stone, TW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Kynurenine Pathway Metabolites as Novel Translational Biological Markers of Irritable Bowel Syndrome: Relationship to Gastrointestinal Function, Cognition and Co-morbid Depression[NCT01304355] | 85 participants (Anticipated) | Observational | 2011-01-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for kynurenine and Colitis Gravis
| Article | Year |
|---|---|
Kynurenine pathway metabolites modulated the comorbidity of IBD and depressive symptoms through the immune response.
Topics: Colitis, Ulcerative; Comorbidity; Depression; Humans; Inflammation; Kynurenine; Tryptophan | 2023 |
Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am | 2013 |
An Insight into the Roles of Dietary Tryptophan and Its Metabolites in Intestinal Inflammation and Inflammatory Bowel Disease.
Topics: Colitis, Ulcerative; Gastrointestinal Microbiome; Humans; Indoles; Inflammatory Bowel Diseases; Kynu | 2021 |
1 trial available for kynurenine and Colitis Gravis
| Article | Year |
|---|---|
Topics: Acetaminophen; Administration, Oral; Adolescent; Adsorption; Adult; Allyl Compounds; Amylopectin; Am | 2013 |
6 other studies available for kynurenine and Colitis Gravis
| Article | Year |
|---|---|
Serum Serotonin Differentiates Between Disease Activity States in Crohn's Patients.
Topics: Adolescent; Adult; Biopsy; C-Reactive Protein; Colitis, Ulcerative; Colon; Crohn Disease; Cytokines; | 2020 |
Tryptophan Metabolism through the Kynurenine Pathway is Associated with Endoscopic Inflammation in Ulcerative Colitis.
Topics: Adolescent; Adult; Aged; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Col | 2018 |
Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry with Electrospray Ionization Quantification of Tryptophan Metabolites and Markers of Gut Health in Serum and Plasma-Application to Clinical and Epidemiology Cohorts.
Topics: Adult; Aged; Biomarkers; Chromatography, High Pressure Liquid; Citrulline; Cohort Studies; Colitis, | 2019 |
IDO1 metabolites activate β-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice.
Topics: Animals; Azoxymethane; beta Catenin; Carcinogens; Cell Proliferation; Colitis; Colitis, Ulcerative; | 2013 |
Bimodal plasma metabolomics strategy identifies novel inflammatory metabolites in inflammatory bowel diseases.
Topics: Adult; Angiotensin II; Case-Control Studies; Colitis, Ulcerative; Crohn Disease; Female; G(M3) Gangl | 2014 |
Levels of purine, kynurenine and lipid peroxidation products in patients with inflammatory bowel disease.
Topics: Adenosine; Case-Control Studies; Colitis, Ulcerative; Crohn Disease; Humans; Inflammatory Bowel Dise | 2003 |