kynurenine has been researched along with Colitis, Granulomatous in 10 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Both the Crohn's disease exclusion diet combined with partial enteral nutrition (CDED+PEN) and exclusive enteral nutrition (EEN) can induce remission in mild-to-moderate pediatric Crohn's disease and are associated with a marked decrease in fecal kynurenine levels." | 3.30 | Sustained Diet-Induced Remission in Pediatric Crohn's Disease Is Associated With Kynurenine and Serotonin Pathways. ( Benninga, MA; Boneh, RS; de Jonge, WJ; Emond, P; Ghiboub, M; Lefèvre, A; Sovran, B; Van Limbergen, JE; Verburgt, CM; Wine, E, 2023) |
| "Crohn's disease (CD) and ulcerative colitis (UC) are inflammatory bowel diseases (IBD) characterized by variable phenotypes." | 1.40 | Bimodal plasma metabolomics strategy identifies novel inflammatory metabolites in inflammatory bowel diseases. ( Bustamante, S; Campbell, B; Hejazi, L; Leong, RW; Pickford, R; Shin, S; Wasinger, VC; Yau, YY, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ghiboub, M | 2 |
| Penny, S | 1 |
| Verburgt, CM | 2 |
| Boneh, RS | 2 |
| Wine, E | 2 |
| Cohen, A | 1 |
| Dunn, KA | 1 |
| Pinto, DM | 1 |
| Benninga, MA | 2 |
| de Jonge, WJ | 2 |
| Levine, A | 1 |
| Van Limbergen, JE | 2 |
| Sovran, B | 1 |
| Lefèvre, A | 1 |
| Emond, P | 1 |
| Manzella, CR | 1 |
| Jayawardena, D | 1 |
| Pagani, W | 1 |
| Li, Y | 1 |
| Alrefai, WA | 1 |
| Bauer, J | 1 |
| Jung, B | 1 |
| Weber, CR | 1 |
| Gill, RK | 1 |
| Agus, A | 1 |
| Planchais, J | 1 |
| Sokol, H | 1 |
| Yau, YY | 1 |
| Leong, RW | 1 |
| Shin, S | 1 |
| Bustamante, S | 1 |
| Pickford, R | 1 |
| Hejazi, L | 1 |
| Campbell, B | 1 |
| Wasinger, VC | 1 |
| Lee, A | 1 |
| Kanuri, N | 2 |
| Zhang, Y | 1 |
| Sayuk, GS | 1 |
| Li, E | 1 |
| Ciorba, MA | 2 |
| Lin, HM | 1 |
| Barnett, MP | 1 |
| Roy, NC | 1 |
| Joyce, NI | 1 |
| Zhu, S | 1 |
| Armstrong, K | 1 |
| Helsby, NA | 1 |
| Ferguson, LR | 1 |
| Rowan, DD | 1 |
| Gupta, NK | 1 |
| Thaker, AI | 1 |
| Riehl, TE | 1 |
| Rowley, CW | 1 |
| Stenson, WF | 1 |
| Forrest, CM | 1 |
| Gould, SR | 1 |
| Darlington, LG | 1 |
| Stone, TW | 1 |
| Torres, MI | 1 |
| López-Casado, MA | 1 |
| Lorite, P | 1 |
| Ríos, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Partial Enteral Nutririon (Modulen) With a Unique Diet to Exclusive Enteral Nutrition (Modulen) for the Treatment of Pediatric Crohn's Disease. A Prospective Randomized Controlled Trial.[NCT01728870] | 74 participants (Actual) | Interventional | 2013-01-31 | Completed | |||
| Involvement of the Gut Microbiota and Its Metabolites in the Pathophysiology of Calcified Aortic Stenosis[NCT06021535] | 100 participants (Anticipated) | Observational | 2024-01-01 | Not yet recruiting | |||
| Kynurenine Pathway Metabolites as Novel Translational Biological Markers of Irritable Bowel Syndrome: Relationship to Gastrointestinal Function, Cognition and Co-morbid Depression[NCT01304355] | 85 participants (Anticipated) | Observational | 2011-01-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for kynurenine and Colitis, Granulomatous
| Article | Year |
|---|---|
Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease.
Topics: Autistic Disorder; Colitis; Communicable Diseases; Crohn Disease; Gastrointestinal Microbiome; Gastr | 2018 |
2 trials available for kynurenine and Colitis, Granulomatous
| Article | Year |
|---|---|
Metabolome Changes With Diet-Induced Remission in Pediatric Crohn's Disease.
Topics: Arginine; Ceramides; Child; Crohn Disease; Diet; Humans; Kynurenine; Metabolome; Prospective Studies | 2022 |
Sustained Diet-Induced Remission in Pediatric Crohn's Disease Is Associated With Kynurenine and Serotonin Pathways.
Topics: Child; Crohn Disease; Diet; Humans; Kynurenine; Melatonin; Prospective Studies; Quinolinic Acid; Rem | 2023 |
7 other studies available for kynurenine and Colitis, Granulomatous
| Article | Year |
|---|---|
Serum Serotonin Differentiates Between Disease Activity States in Crohn's Patients.
Topics: Adolescent; Adult; Biopsy; C-Reactive Protein; Colitis, Ulcerative; Colon; Crohn Disease; Cytokines; | 2020 |
Bimodal plasma metabolomics strategy identifies novel inflammatory metabolites in inflammatory bowel diseases.
Topics: Adult; Angiotensin II; Case-Control Studies; Colitis, Ulcerative; Crohn Disease; Female; G(M3) Gangl | 2014 |
IDO1 and IDO2 non-synonymous gene variants: correlation with crohn's disease risk and clinical phenotype.
Topics: Adult; Case-Control Studies; Crohn Disease; Female; Genetic Predisposition to Disease; Humans; Indol | 2014 |
Metabolomic analysis identifies inflammatory and noninflammatory metabolic effects of genetic modification in a mouse model of Crohn's disease.
Topics: Animals; Chromatography, Liquid; Cluster Analysis; Crohn Disease; Disease Models, Animal; Germ-Free | 2010 |
Serum analysis of tryptophan catabolism pathway: correlation with Crohn's disease activity.
Topics: Adult; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Crohn Disease; Female | 2012 |
Levels of purine, kynurenine and lipid peroxidation products in patients with inflammatory bowel disease.
Topics: Adenosine; Case-Control Studies; Colitis, Ulcerative; Crohn Disease; Humans; Inflammatory Bowel Dise | 2003 |
Tryptophan metabolism and indoleamine 2,3-dioxygenase expression in coeliac disease.
Topics: Biopsy; Celiac Disease; Child; Child, Preschool; Chromatography, High Pressure Liquid; Crohn Disease | 2007 |