Page last updated: 2024-10-18

kynurenine and Chronic Disease

kynurenine has been researched along with Chronic Disease in 37 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).

Research Excerpts

ExcerptRelevanceReference
"It was our objective to increase the body of data regarding the value of kynurenine as a biomarker in chronic heart failure (CHF)."7.91Plasma Kynurenine Predicts Severity and Complications of Heart Failure and Associates with Established Biochemical and Clinical Markers of Disease. ( Armbruster, FP; Bankovic, D; Boschann, F; Dschietzig, TB; Kellner, KH; Klüsener, R; Meinitzer, A; Melzer, C; Mitrovic, V; Ruppert, J; Sasse, K, 2019)
" Here we show that a superoxide-dependent step in tryptophan metabolism along the kynurenine pathway is blocked in CGD mice with lethal pulmonary aspergillosis, leading to unrestrained Vgamma1(+) gammadelta T-cell reactivity, dominant production of interleukin (IL)-17, defective regulatory T-cell activity and acute inflammatory lung injury."7.74Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease. ( Bistoni, F; D'Angelo, C; De Luca, A; Fallarino, F; Fioretti, MC; Grohmann, U; Montagnoli, C; Puccetti, P; Romani, L; Segal, BH; Vacca, C; Zelante, T, 2008)
"The results of our clinical observations of 102 patients with chronic glomerulonephritis with normal renal function have shown that hyperkynureninemia in 22."7.70Kynurenine and neopterin in chronic glomerulonephritis. ( Bratslavska, O; Fuchs, D; Groma, V; Martinsons, A; Rudzite, V; Widner, B, 1999)
"Kynurenines are a wide range of catabolites which derive from tryptophan through the "Kynurenine Pathway" (KP)."6.53The Kynurenine Pathway in the Acute and Chronic Phases of Cerebral Ischemia. ( Ballesteros, I; Cuartero, MI; de la Parra, J; García-Culebras, A; Lizasoain, I; Moro, MÁ, 2016)
"Chronic inflammation is associated with physical frailty and functional decline in older adults; however, the molecular mechanisms of this linkage are not understood."5.56Kynurenines link chronic inflammation to functional decline and physical frailty. ( Abadir, PM; Chung, T; de Cabo, R; Ferrucci, L; Hoke, A; Joca, H; Khadeer, M; Le, A; Lovett, J; Moaddel, R; Tian, J; Walston, J; Ward, C; Westbrook, R; Xue, QL; Yang, H, 2020)
"The kynurenine blood level was found to correlate with seizures."5.27[Elevated kynurenine concentration in the blood serum of children with epilepsy and bronchial asthma]. ( Buzdin, VV; Ivanova, NA; Nikitina, ZS; Ryzhov, IV, 1988)
"It was our objective to increase the body of data regarding the value of kynurenine as a biomarker in chronic heart failure (CHF)."3.91Plasma Kynurenine Predicts Severity and Complications of Heart Failure and Associates with Established Biochemical and Clinical Markers of Disease. ( Armbruster, FP; Bankovic, D; Boschann, F; Dschietzig, TB; Kellner, KH; Klüsener, R; Meinitzer, A; Melzer, C; Mitrovic, V; Ruppert, J; Sasse, K, 2019)
"We demonstrated that confronting mice to the Unpredictable Chronic Mild Stress (UCMS) procedure-a validated model of stress-induced depression-results in behavioural alterations and biochemical changes in the kynurenine pathway (KP), suspected to modify the glutamatergic neurotransmission through the imbalance between downstream metabolites such as 3-hydroxykynurenine, quinolinic and kynurenic acids."3.83Chronic Treatment with the IDO1 Inhibitor 1-Methyl-D-Tryptophan Minimizes the Behavioural and Biochemical Abnormalities Induced by Unpredictable Chronic Mild Stress in Mice - Comparison with Fluoxetine. ( Barone, PR; Belzung, C; Callebert, J; Guillemin, GJ; Laugeray, A; Launay, JM; Mutlu, O, 2016)
" Here we show that a superoxide-dependent step in tryptophan metabolism along the kynurenine pathway is blocked in CGD mice with lethal pulmonary aspergillosis, leading to unrestrained Vgamma1(+) gammadelta T-cell reactivity, dominant production of interleukin (IL)-17, defective regulatory T-cell activity and acute inflammatory lung injury."3.74Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease. ( Bistoni, F; D'Angelo, C; De Luca, A; Fallarino, F; Fioretti, MC; Grohmann, U; Montagnoli, C; Puccetti, P; Romani, L; Segal, BH; Vacca, C; Zelante, T, 2008)
"The results of our clinical observations of 102 patients with chronic glomerulonephritis with normal renal function have shown that hyperkynureninemia in 22."3.70Kynurenine and neopterin in chronic glomerulonephritis. ( Bratslavska, O; Fuchs, D; Groma, V; Martinsons, A; Rudzite, V; Widner, B, 1999)
"Kynurenines are a wide range of catabolites which derive from tryptophan through the "Kynurenine Pathway" (KP)."2.53The Kynurenine Pathway in the Acute and Chronic Phases of Cerebral Ischemia. ( Ballesteros, I; Cuartero, MI; de la Parra, J; García-Culebras, A; Lizasoain, I; Moro, MÁ, 2016)
"Chronic inflammation is associated with physical frailty and functional decline in older adults; however, the molecular mechanisms of this linkage are not understood."1.56Kynurenines link chronic inflammation to functional decline and physical frailty. ( Abadir, PM; Chung, T; de Cabo, R; Ferrucci, L; Hoke, A; Joca, H; Khadeer, M; Le, A; Lovett, J; Moaddel, R; Tian, J; Walston, J; Ward, C; Westbrook, R; Xue, QL; Yang, H, 2020)
" This stimulation induces indoleamine 2,3-dioxygenase (IDO), an enzyme that reduces the tryptophan bioavailability to synthesize serotonin."1.51Chronic Mild Stress Alters Kynurenine Pathways Changing the Glutamate Neurotransmission in Frontal Cortex of Rats. ( Caso, JR; García-Bueno, B; Leza, JC; Madrigal, JLM; Martín-Hernández, D; Tendilla-Beltrán, H, 2019)
"Geriatric depression is a costly health issue, but little is known about its physiological underpinnings."1.39Aging leads to prolonged duration of inflammation-induced depression-like behavior caused by Bacillus Calmette-Guérin. ( Dantzer, R; Kelley, KW; Lawson, MA; McCusker, RH; O'Connor, JC; Rodriguez-Zas, SL, 2013)
"The kynurenine blood level was found to correlate with seizures."1.27[Elevated kynurenine concentration in the blood serum of children with epilepsy and bronchial asthma]. ( Buzdin, VV; Ivanova, NA; Nikitina, ZS; Ryzhov, IV, 1988)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19909 (24.32)18.7374
1990's4 (10.81)18.2507
2000's5 (13.51)29.6817
2010's17 (45.95)24.3611
2020's2 (5.41)2.80

Authors

AuthorsStudies
Westbrook, R1
Chung, T1
Lovett, J1
Ward, C1
Joca, H1
Yang, H1
Khadeer, M1
Tian, J1
Xue, QL1
Le, A1
Ferrucci, L1
Moaddel, R1
de Cabo, R1
Hoke, A1
Walston, J1
Abadir, PM1
Joisten, N1
Ruas, JL1
Braidy, N1
Guillemin, GJ2
Zimmer, P1
Gelpi, M1
Hartling, HJ1
Ueland, PM1
Ullum, H1
Trøseid, M1
Nielsen, SD1
Nagy, BM1
Nagaraj, C1
Meinitzer, A2
Sharma, N1
Papp, R1
Foris, V1
Ghanim, B1
Kwapiszewska, G1
Kovacs, G1
Klepetko, W1
Pieber, TR1
Mangge, H1
Olschewski, H1
Olschewski, A1
Martín-Hernández, D1
Tendilla-Beltrán, H1
Madrigal, JLM1
García-Bueno, B1
Leza, JC1
Caso, JR1
Hüfner, K1
Fuchs, D3
Blauth, M1
Sperner-Unterweger, B1
Su, J1
Wang, J1
Ma, Y1
Li, Q1
Yang, Y1
Huang, L1
Wang, H1
Li, H1
Wang, Z1
Tong, J1
Huang, D1
Bai, X1
Yu, M1
Bu, L1
Fei, J1
Huang, F1
Dschietzig, TB1
Kellner, KH1
Sasse, K1
Boschann, F1
Klüsener, R1
Ruppert, J1
Armbruster, FP1
Bankovic, D1
Mitrovic, V1
Melzer, C1
Kelley, KW1
O'Connor, JC1
Lawson, MA1
Dantzer, R1
Rodriguez-Zas, SL1
McCusker, RH1
Gibney, SM1
Fagan, EM1
Waldron, AM1
O'Byrne, J1
Connor, TJ1
Harkin, A1
Cuartero, MI1
de la Parra, J1
García-Culebras, A1
Ballesteros, I1
Lizasoain, I1
Moro, MÁ1
Schwieler, L1
Larsson, MK1
Skogh, E1
Kegel, ME1
Orhan, F1
Abdelmoaty, S1
Finn, A1
Bhat, M1
Samuelsson, M1
Lundberg, K1
Dahl, ML1
Sellgren, C1
Schuppe-Koistinen, I1
Svensson, C1
Erhardt, S1
Engberg, G1
Mahmoud, ME1
Ihara, F1
Fereig, RM1
Nishimura, M1
Nishikawa, Y1
Laugeray, A2
Launay, JM2
Callebert, J2
Mutlu, O1
Belzung, C2
Barone, PR2
Pawlak, K1
Tankiewicz, J1
Mysliwiec, M1
Pawlak, D1
Surget, A1
Bercik, P1
Verdu, EF1
Foster, JA1
Macri, J1
Potter, M1
Huang, X1
Malinowski, P1
Jackson, W1
Blennerhassett, P1
Neufeld, KA1
Lu, J1
Khan, WI1
Corthesy-Theulaz, I1
Cherbut, C1
Bergonzelli, GE1
Collins, SM1
Zádori, D1
Klivényi, P1
Plangár, I1
Toldi, J1
Vécsei, L1
Knubel, CP1
Martínez, FF1
Acosta Rodríguez, EV1
Altamirano, A1
Rivarola, HW1
Diaz Luján, C1
Fretes, RE1
Cervi, L1
Motrán, CC1
Kwon, S1
Lee, B1
Yeom, M1
Sur, BJ1
Kim, M1
Kim, ST1
Park, HJ1
Lee, H1
Hahm, DH1
Schroecksnadel, K1
Wirleitner, B1
Melchior, D1
Le Floc'h, N1
Sève, B1
Mackay, GM1
Forrest, CM1
Stoy, N1
Christofides, J1
Egerton, M1
Stone, TW1
Darlington, LG1
Romani, L1
Fallarino, F1
De Luca, A1
Montagnoli, C1
D'Angelo, C1
Zelante, T1
Vacca, C1
Bistoni, F1
Fioretti, MC1
Grohmann, U1
Segal, BH1
Puccetti, P1
Borisenko, KK1
Guseĭnova, RS2
Meyer, KC1
Arend, RA1
Kalayoglu, MV1
Rosenthal, NS1
Byrne, GI1
Brown, RR1
Issa, F1
Gerhardt, GA1
Bartko, JJ1
Suddath, RL1
Lynch, M1
Gamache, PH1
Freedman, R1
Wyatt, RJ1
Kirch, DG1
Du, F1
Williamson, J1
Bertram, E1
Lothman, E1
Okuno, E1
Schwarcz, R1
Martinsons, A1
Rudzite, V1
Groma, V1
Bratslavska, O1
Widner, B1
Crow, TJ1
Baker, HF1
Cross, AJ1
Joseph, MH1
Lofthouse, R1
Longden, A1
Owen, F1
Riley, GJ1
Glover, V1
Killpack, WS1
Rossouw, JE1
Labadarios, D1
Davis, M1
Williams, R1
Ivanova, NA1
Ryzhov, IV1
Buzdin, VV1
Nikitina, ZS1
Heeley, AF1
Heeley, ME1
Hardy, J1
Soothill, JF1
Kontsevaia, NG1
Kondrat'ev, VG1
Iaia, E1
Di Lernia, C1
Sconosciuto, C1
Knapp, A1
Wolfram, G1
Posch, W1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Longitudinal Study of Inflammatory Pathways in Depression[NCT04159207]160 participants (Anticipated)Observational2019-10-01Recruiting
The Safety and Effectiveness of Probiotic Supplementation on Bipolar Depression: a Proof of Concept Randomized Controlled Trial[NCT02155972]Phase 216 participants (Actual)Interventional2013-05-31Terminated (stopped due to The trial was terminated because of inability to recruit the needed number of participants)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for kynurenine and Chronic Disease

ArticleYear
The kynurenine pathway in chronic diseases: a compensatory mechanism or a driving force?
    Trends in molecular medicine, 2021, Volume: 27, Issue:10

    Topics: Chronic Disease; Humans; Kynurenic Acid; Kynurenine; Quinolinic Acid; Tryptophan

2021
The Kynurenine Pathway in the Acute and Chronic Phases of Cerebral Ischemia.
    Current pharmaceutical design, 2016, Volume: 22, Issue:8

    Topics: Acute Disease; Brain Ischemia; Chronic Disease; Humans; Kynurenine; Metabolic Networks and Pathways;

2016
Endogenous neuroprotection in chronic neurodegenerative disorders: with particular regard to the kynurenines.
    Journal of cellular and molecular medicine, 2011, Volume: 15, Issue:4

    Topics: Animals; Chronic Disease; Cytoprotection; Humans; Kynurenine; Mitochondria; Neurodegenerative Diseas

2011

Trials

1 trial available for kynurenine and Chronic Disease

ArticleYear
A multidimensional approach to analysis of cerebrospinal fluid biogenic amines in schizophrenia: I. Comparisons with healthy control subjects and neuroleptic-treated/unmedicated pairs analyses.
    Psychiatry research, 1994, Volume: 52, Issue:3

    Topics: Adult; Biogenic Amines; Chromatography, High Pressure Liquid; Chronic Disease; Dopamine; Double-Blin

1994

Other Studies

33 other studies available for kynurenine and Chronic Disease

ArticleYear
Kynurenines link chronic inflammation to functional decline and physical frailty.
    JCI insight, 2020, 08-20, Volume: 5, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Animals; Arginine; Chronic Disease; Cytokines; Disease Models, Anima

2020
Tryptophan catabolism and immune activation in primary and chronic HIV infection.
    BMC infectious diseases, 2017, 05-16, Volume: 17, Issue:1

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes

2017
Importance of kynurenine in pulmonary hypertension.
    American journal of physiology. Lung cellular and molecular physiology, 2017, Nov-01, Volume: 313, Issue:5

    Topics: Adolescent; Adult; Aged; Animals; Child; Chronic Disease; Female; Humans; Hypertension, Pulmonary; K

2017
Chronic Mild Stress Alters Kynurenine Pathways Changing the Glutamate Neurotransmission in Frontal Cortex of Rats.
    Molecular neurobiology, 2019, Volume: 56, Issue:1

    Topics: Animals; Antidepressive Agents; Chronic Disease; Cytokines; Frontal Lobe; Glutamate Plasma Membrane

2019
How acute and chronic physical disease may influence mental health - An Analysis of neurotransmitter precursor amino acid levels.
    Psychoneuroendocrinology, 2019, Volume: 106

    Topics: Acute Disease; Adult; Aged; Amino Acids; Anxiety Disorders; C-Reactive Protein; Chronic Disease; Dep

2019
Inflammation associated with chronic heart failure leads to enhanced susceptibility to depression.
    The FEBS journal, 2019, Volume: 286, Issue:14

    Topics: Animals; Brain; Chronic Disease; Cytokines; Depression; Heart Failure; Hypothalamo-Hypophyseal Syste

2019
Plasma Kynurenine Predicts Severity and Complications of Heart Failure and Associates with Established Biochemical and Clinical Markers of Disease.
    Kidney & blood pressure research, 2019, Volume: 44, Issue:4

    Topics: Aged; Aged, 80 and over; Biomarkers; Chronic Disease; Female; Heart Failure; Humans; Immunoassay; Ky

2019
Aging leads to prolonged duration of inflammation-induced depression-like behavior caused by Bacillus Calmette-Guérin.
    Brain, behavior, and immunity, 2013, Volume: 32

    Topics: Aging; Anhedonia; Animals; Behavior, Animal; Body Weight; Chronic Disease; Depression; Hindlimb Susp

2013
Inhibition of stress-induced hepatic tryptophan 2,3-dioxygenase exhibits antidepressant activity in an animal model of depressive behaviour.
    The international journal of neuropsychopharmacology, 2014, Volume: 17, Issue:6

    Topics: Allopurinol; Animals; Antidepressive Agents; Cerebral Cortex; Chronic Disease; Corticosterone; Depre

2014
Increased levels of IL-6 in the cerebrospinal fluid of patients with chronic schizophrenia--significance for activation of the kynurenine pathway.
    Journal of psychiatry & neuroscience : JPN, 2015, Volume: 40, Issue:2

    Topics: Adult; Astrocytes; Cells, Cultured; Cerebral Cortex; Chronic Disease; Female; Humans; Interleukin-6;

2015
Induction of depression-related behaviors by reactivation of chronic Toxoplasma gondii infection in mice.
    Behavioural brain research, 2016, Feb-01, Volume: 298, Issue:Pt B

    Topics: Animals; Brain; Chronic Disease; Depressive Disorder; Dietary Sucrose; Disease Models, Animal; Dopam

2016
Chronic Treatment with the IDO1 Inhibitor 1-Methyl-D-Tryptophan Minimizes the Behavioural and Biochemical Abnormalities Induced by Unpredictable Chronic Mild Stress in Mice - Comparison with Fluoxetine.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Animals; Antidepressive Agents, Second-Generation; Chronic Disease; Cytokines; Depression; Fluoxetin

2016
Tissue factor/its pathway inhibitor system and kynurenines in chronic kidney disease patients on conservative treatment.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 2009, Volume: 20, Issue:7

    Topics: Adult; Aged; Case-Control Studies; Chronic Disease; Female; Humans; Kidney Diseases; Kynurenine; Lip

2009
Peripheral and cerebral metabolic abnormalities of the tryptophan-kynurenine pathway in a murine model of major depression.
    Behavioural brain research, 2010, Jun-26, Volume: 210, Issue:1

    Topics: Animals; Brain; Chronic Disease; Depressive Disorder, Major; Disease Models, Animal; Hydroxyindoleac

2010
Chronic gastrointestinal inflammation induces anxiety-like behavior and alters central nervous system biochemistry in mice.
    Gastroenterology, 2010, Volume: 139, Issue:6

    Topics: Animals; Anxiety; Behavior, Animal; Brain-Derived Neurotrophic Factor; Chronic Disease; Colitis; Cyt

2010
3-Hydroxy kynurenine treatment controls T. cruzi replication and the inflammatory pathology preventing the clinical symptoms of chronic Chagas disease.
    PloS one, 2011, Volume: 6, Issue:10

    Topics: Animals; Chagas Disease; Chronic Disease; Female; Inflammation; Interferon-gamma; Kynurenine; Mice;

2011
Modulatory effects of acupuncture on murine depression-like behavior following chronic systemic inflammation.
    Brain research, 2012, Sep-07, Volume: 1472

    Topics: Acupuncture Therapy; Animals; Behavior, Animal; Brain; Chromatography, High Pressure Liquid; Chronic

2012
Anemia and congestive heart failure.
    Circulation, 2003, Aug-12, Volume: 108, Issue:6

    Topics: Anemia; Causality; Cell Division; Chronic Disease; Comorbidity; Dioxygenases; Heart Failure; Hematop

2003
Effects of chronic lung inflammation on tryptophan metabolism in piglets.
    Advances in experimental medicine and biology, 2003, Volume: 527

    Topics: Animals; Chronic Disease; Freund's Adjuvant; Kynurenine; Pneumonia; Sus scrofa; Swine Diseases; Tryp

2003
Tryptophan metabolism and oxidative stress in patients with chronic brain injury.
    European journal of neurology, 2006, Volume: 13, Issue:1

    Topics: Adult; Aged; Brain Injuries; Chromatography, High Pressure Liquid; Chronic Disease; Enzyme-Linked Im

2006
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.
    Nature, 2008, Jan-10, Volume: 451, Issue:7175

    Topics: Animals; Aspergillosis; Aspergillus fumigatus; Chronic Disease; Disease Models, Animal; Granulomatou

2008
[Tryptophan metabolism in psoriasis].
    Vestnik dermatologii i venerologii, 1981, Issue:9

    Topics: Adult; Chronic Disease; Circadian Rhythm; Female; Humans; Kynurenine; Male; Middle Aged; Psoriasis;

1981
Tryptophan metabolism in chronic inflammatory lung disease.
    The Journal of laboratory and clinical medicine, 1995, Volume: 126, Issue:6

    Topics: Actins; Adult; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid; Chronic Disease;

1995
Kynurenine pathway enzymes in a rat model of chronic epilepsy: immunohistochemical study of activated glial cells.
    Neuroscience, 1993, Volume: 55, Issue:4

    Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; Animals; Astrocytes; Cell Death; Cerebral Cortex; Chronic Dis

1993
Kynurenine and neopterin in chronic glomerulonephritis.
    Advances in experimental medicine and biology, 1999, Volume: 467

    Topics: Biomarkers; Chronic Disease; Creatinine; Fasting; Glomerular Filtration Rate; Glomerulonephritis; Gl

1999
Monoamine mechanisms in chronic schizophrenia: post-mortem neurochemical findings.
    The British journal of psychiatry : the journal of mental science, 1979, Volume: 134

    Topics: Aged; Brain Chemistry; Catechol O-Methyltransferase; Chronic Disease; Dopamine; Dopamine beta-Hydrox

1979
[Tryptophan metabolic indices in allergic dermatoses].
    Vestnik dermatologii i venerologii, 1979, Issue:4

    Topics: Chronic Disease; Dermatitis, Atopic; Female; Humans; Kynurenic Acid; Kynurenine; Male; Prurigo; Pyri

1979
The degradation of tryptophan in severe liver disease.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1978, Volume: 48, Issue:3

    Topics: Acute Disease; Chronic Disease; Humans; Kynurenine; Liver Diseases; Tryptophan; Vitamins

1978
[Elevated kynurenine concentration in the blood serum of children with epilepsy and bronchial asthma].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1988, Volume: 88, Issue:6

    Topics: Adolescent; Asthma; Child; Child, Preschool; Chronic Disease; Epilepsy; Female; Humans; Kynurenine;

1988
A disorder of tryptophan metabolism in chronic granulomatous disease.
    Archives of disease in childhood, 1970, Volume: 45, Issue:242

    Topics: Child; Child, Preschool; Chromatography, Paper; Chronic Disease; Granuloma; Humans; Infant, Newborn;

1970
[Balance and metabolism of tryptophan in pneumonia].
    Terapevticheskii arkhiv, 1971, Volume: 43, Issue:5

    Topics: Adult; Chronic Disease; Focal Infection; Humans; Kynurenine; Male; Pneumonia; Spectrophotometry; Try

1971
[Behavior of various enzymes in the serum, kynurenine, lactates, pyruvates, during a course of acute and chronic bronchopneumopathies: relationship to arterial hemogasometry and spirographic data].
    Giornale di pneumologia, 1971, Volume: 15, Issue:1

    Topics: Acute Disease; Adult; Blood Gas Analysis; Chronic Disease; Humans; Kynurenine; Lactates; Pyruvates;

1971
[Chronic urticaria and vitamin B6 dependent disorders in tryptophan metabolism].
    Dermatologische Monatschrift, 1970, Volume: 156, Issue:3

    Topics: Adolescent; Adult; Aged; Child; Chronic Disease; Female; Humans; Kynurenine; Male; Middle Aged; Pyri

1970