Page last updated: 2024-10-19

kynurenine and Cancer of Skin

kynurenine has been researched along with Cancer of Skin in 11 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Research Excerpts

ExcerptRelevanceReference
"The kynurenine pathway is a major pathway of tryptophan metabolism leading to nicotinamide adenine dinucleotide (NAD+) production."7.01PPARs and the Kynurenine Pathway in Melanoma-Potential Biological Interactions. ( Gerkowicz, A; Krasowska, D; Walczak, K, 2023)
" This study investigated the clinical relevance of IDO1 expression by immune cells in the lymph nodes and blood and of the serum kynurenine/tryptophan (Kyn/Trp) ratio in 65 systemic treatment naïve stage I-III melanoma patients."4.02Clinical Relevance of Serum Kyn/Trp Ratio and Basal and IFNγ-Upregulated IDO1 Expression in Peripheral Monocytes in Early Stage Melanoma. ( Allorge, D; Brochez, L; Demeyer, A; Ferdinande, L; Haspeslagh, M; Hennart, B; Meireson, A; Ost, P; Spaas, M; Sundahl, N, 2021)
"The kynurenine pathway is a major pathway of tryptophan metabolism leading to nicotinamide adenine dinucleotide (NAD+) production."3.01PPARs and the Kynurenine Pathway in Melanoma-Potential Biological Interactions. ( Gerkowicz, A; Krasowska, D; Walczak, K, 2023)
"Kynurenine metabolites inhibit T-cell proliferation resulting in cell growth arrest."2.82The involvement of a chemokine receptor antagonist CTCE-9908 and kynurenine metabolites in cancer development. ( Basson, C; Bipath, P; Hlophe, Y; Joubert, AM; Nkandeu, DS; Nyakudya, T; Serem, JC, 2022)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (27.27)24.3611
2020's7 (63.64)2.80

Authors

AuthorsStudies
Meireson, A1
Ferdinande, L1
Haspeslagh, M1
Hennart, B1
Allorge, D1
Ost, P1
Sundahl, N1
Spaas, M1
Demeyer, A1
Brochez, L1
Jankovskaja, S2
Morin, M1
Gustafsson, A1
Anderson, CD1
Lehoczki, B1
Engblom, J2
Björklund, S2
Rezeli, M2
Marko-Varga, G2
Ruzgas, T2
Nkandeu, DS1
Basson, C1
Joubert, AM1
Serem, JC1
Bipath, P1
Nyakudya, T1
Hlophe, Y1
Hubková, B1
Valko-Rokytovská, M1
Čižmárová, B1
Zábavníková, M1
Mareková, M1
Birková, A1
Walczak, K2
Gerkowicz, A1
Krasowska, D1
Rad Pour, S1
Morikawa, H1
Kiani, NA1
Yang, M1
Azimi, A1
Shafi, G1
Shang, M1
Baumgartner, R1
Ketelhuth, DFJ1
Kamleh, MA1
Wheelock, CE1
Lundqvist, A1
Hansson, J1
Tegnér, J1
Szelest, M1
Plech, T1
Metz, R1
Smith, C1
DuHadaway, JB1
Chandler, P1
Baban, B1
Merlo, LM1
Pigott, E1
Keough, MP1
Rust, S1
Mellor, AL1
Mandik-Nayak, L1
Muller, AJ1
Prendergast, GC1
Lo, BK1
Jalili, RB1
Zloty, D1
Ghahary, A1
Cowan, B1
Dutz, JP1
Carr, N1
Shapiro, J1
McElwee, KJ1
Binazzi, M1

Reviews

3 reviews available for kynurenine and Cancer of Skin

ArticleYear
The involvement of a chemokine receptor antagonist CTCE-9908 and kynurenine metabolites in cancer development.
    Cell biochemistry and function, 2022, Volume: 40, Issue:6

    Topics: Chemokine CXCL12; Chemokines, CXC; Child; Humans; Kynurenine; Melanoma; Peptides; Receptors, CXCR4;

2022
PPARs and the Kynurenine Pathway in Melanoma-Potential Biological Interactions.
    International journal of molecular sciences, 2023, 02-04, Volume: 24, Issue:4

    Topics: Humans; Kynurenine; Melanoma; Peroxisome Proliferator-Activated Receptors; Skin Neoplasms; Tryptopha

2023
A New Insight into the Potential Role of Tryptophan-Derived AhR Ligands in Skin Physiological and Pathological Processes.
    International journal of molecular sciences, 2021, Jan-22, Volume: 22, Issue:3

    Topics: Animals; Carbazoles; Chloracne; Dermatitis, Atopic; Humans; Hyperpigmentation; Kynurenic Acid; Kynur

2021

Other Studies

8 other studies available for kynurenine and Cancer of Skin

ArticleYear
Clinical Relevance of Serum Kyn/Trp Ratio and Basal and IFNγ-Upregulated IDO1 Expression in Peripheral Monocytes in Early Stage Melanoma.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Adult; Cells, Cultured; Enzyme Induction; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inte

2021
Non-Invasive, Topical Sampling of Potential, Low-Molecular Weight, Skin Cancer Biomarkers: A Study on Healthy Volunteers.
    Analytical chemistry, 2022, 04-19, Volume: 94, Issue:15

    Topics: Biomarkers; Biomarkers, Tumor; Healthy Volunteers; Humans; Kynurenine; Molecular Weight; Phenylalani

2022
Tryptophan: Its Metabolism along the Kynurenine, Serotonin, and Indole Pathway in Malignant Melanoma.
    International journal of molecular sciences, 2022, Aug-15, Volume: 23, Issue:16

    Topics: Humans; Indoles; Kynurenine; Melanoma; Melanoma, Cutaneous Malignant; Serotonin; Skin Neoplasms; Try

2022
Exhaustion of CD4+ T-cells mediated by the Kynurenine Pathway in Melanoma.
    Scientific reports, 2019, 08-21, Volume: 9, Issue:1

    Topics: B7-H1 Antigen; CD4-Positive T-Lymphocytes; Cell Line; Cell Proliferation; Coculture Techniques; Cult

2019
Non-invasive skin sampling of tryptophan/kynurenine ratio in vitro towards a skin cancer biomarker.
    Scientific reports, 2021, 01-12, Volume: 11, Issue:1

    Topics: Animals; Biomarkers, Tumor; Cell Membrane Permeability; Electric Conductivity; Kynurenine; Skin; Ski

2021
IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation.
    International immunology, 2014, Volume: 26, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cytokines; Dendritic Cells; Female; Gene Exp

2014
CXCR3 ligands promote expression of functional indoleamine 2,3-dioxygenase in basal cell carcinoma keratinocytes.
    The British journal of dermatology, 2011, Volume: 165, Issue:5

    Topics: Carcinoma, Basal Cell; DNA, Complementary; Female; Humans; Immunohistochemistry; Indoleamine-Pyrrole

2011
Some research on parapsoriasis and lymphomas.
    Archives for dermatological research = Archiv fur dermatologische Forschung, 1977, Mar-25, Volume: 258, Issue:1

    Topics: Adult; Humans; Kynurenine; Lymphoma; Male; Middle Aged; Nicotinic Acids; Parapsoriasis; Precancerous

1977