Page last updated: 2024-10-19

kynurenine and Cancer of Prostate

kynurenine has been researched along with Cancer of Prostate in 15 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Research Excerpts

ExcerptRelevanceReference
"21 adult breast and prostate cancer patients of the TOP study (NCT02883699) were randomized to intervention programs of 12 weeks of (1) endurance standard training or (2) endurance polarized training after a cardiopulmonary exercise test (CPET)."3.01Different endurance exercises modulate NK cell cytotoxic and inhibiting receptors. ( Pal, A; Rosenberger, F; Schlüter, K; Schneider, J; Steindorf, K; Wiskemann, J; Zimmer, P, 2021)
"Comparing the tumor tissues from prostatic cancer patients, we found elevated expression of tryptophan 2, 3-dioxygenase 2 (TDO2), and elevated Trp metabolism in chemo-resistant tumor tissues."1.62Tryptophan metabolism induced by TDO2 promotes prostatic cancer chemotherapy resistance in a AhR/c-Myc dependent manner. ( Guan, W; Li, F; Zhang, Y; Zhang, Z; Zhao, Z, 2021)
"inoculated with AT-2 rat prostate cancer cells negative for expression of Trp catabolic enzymes."1.56Induction of tryptophan hydroxylase in the liver of s.c. tumor model of prostate cancer. ( Hagiwara, A; Miyagi, Y; Nakamura, Y; Nishimoto, R; Ueno, S, 2020)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19904 (26.67)18.7374
1990's0 (0.00)18.2507
2000's1 (6.67)29.6817
2010's5 (33.33)24.3611
2020's5 (33.33)2.80

Authors

AuthorsStudies
Pal, A1
Schneider, J1
Schlüter, K1
Steindorf, K1
Wiskemann, J1
Rosenberger, F1
Zimmer, P1
Li, F1
Zhao, Z1
Zhang, Z1
Zhang, Y1
Guan, W1
Mudhish, EA1
Siddique, AB1
Ebrahim, HY1
Abdelwahed, KS1
King, JA1
El Sayed, KA1
Delkov, D1
Yoanıdu, L1
Tomov, D1
Stoyanova, R1
Dechev, I1
Uzunova, Y1
Hagiwara, A1
Nakamura, Y1
Nishimoto, R1
Ueno, S1
Miyagi, Y1
Khan, A1
Choi, SA1
Na, J1
Pamungkas, AD1
Jung, KJ1
Jee, SH1
Park, YH1
Rodríguez-Blanco, G1
Burgers, PC1
Dekker, LJ1
Vredenbregt-van den Berg, MS1
Ijzermans, JN1
Schenk-Braat, EA1
Jenster, G1
Luider, TM1
Pichler, R1
Fritz, J1
Heidegger, I1
Steiner, E1
Culig, Z1
Klocker, H1
Fuchs, D1
Feder-Mengus, C1
Wyler, S1
Hudolin, T1
Ruszat, R1
Bubendorf, L1
Chiarugi, A1
Pittelli, M1
Weber, WP1
Bachmann, A1
Gasser, TC1
Sulser, T1
Heberer, M1
Spagnoli, GC1
Provenzano, M1
Källberg, E1
Wikström, P1
Bergh, A1
Ivars, F1
Leanderson, T1
Gamagedara, S1
Kaczmarek, AT1
Jiang, Y1
Cheng, X2
Rupasinghe, M1
Ma, Y1
BENASSI, CA1
PERISSINOTTO, B1
ALLEGRI, G1
Wolf, H2
Brown, RR2
Al-Hadithi, NA1
Madsen, PO1

Trials

1 trial available for kynurenine and Cancer of Prostate

ArticleYear
Different endurance exercises modulate NK cell cytotoxic and inhibiting receptors.
    European journal of applied physiology, 2021, Volume: 121, Issue:12

    Topics: Breast Neoplasms; Cells, Cultured; Endurance Training; Exercise Test; Exercise Therapy; Female; Huma

2021

Other Studies

14 other studies available for kynurenine and Cancer of Prostate

ArticleYear
Tryptophan metabolism induced by TDO2 promotes prostatic cancer chemotherapy resistance in a AhR/c-Myc dependent manner.
    BMC cancer, 2021, Oct-17, Volume: 21, Issue:1

    Topics: Animals; ATP-Binding Cassette Transporters; Basic Helix-Loop-Helix Transcription Factors; Cell Line,

2021
The Tobacco β-Cembrenediol: A Prostate Cancer Recurrence Suppressor Lead and Prospective Scaffold via Modulation of Indoleamine 2,3-Dioxygenase and Tryptophan Dioxygenase.
    Nutrients, 2022, Apr-04, Volume: 14, Issue:7

    Topics: Androgens; Animals; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Mice; Mice, Nude

2022
Oncometabolites in urine - a new opportunity for detection and prognosis of the clinical progress of verified prostate cancer-a pilot study.
    Turkish journal of medical sciences, 2022, Volume: 52, Issue:3

    Topics: Adult; Aged; beta-Alanine; Cross-Sectional Studies; Ethanolamines; Humans; Isoleucine; Kynurenine; M

2022
Induction of tryptophan hydroxylase in the liver of s.c. tumor model of prostate cancer.
    Cancer science, 2020, Volume: 111, Issue:4

    Topics: Animals; Chromatography, Liquid; Disease Models, Animal; Humans; Kynurenine; Liver; Liver Neoplasms;

2020
Noninvasive Serum Metabolomic Profiling Reveals Elevated Kynurenine Pathway's Metabolites in Humans with Prostate Cancer.
    Journal of proteome research, 2019, 04-05, Volume: 18, Issue:4

    Topics: Aged; Biomarkers, Tumor; Humans; Kynurenine; Male; Metabolome; Metabolomics; Middle Aged; ortho-Amin

2019
Serum kynurenine/tryptophan ratio is not a potential marker for detecting prostate cancer.
    Clinical biochemistry, 2014, Volume: 47, Issue:13-14

    Topics: Aged; Biomarkers; Case-Control Studies; Humans; Kynurenine; Male; Middle Aged; Prostatic Neoplasms;

2014
Predictive and prognostic role of serum neopterin and tryptophan breakdown in prostate cancer.
    Cancer science, 2017, Volume: 108, Issue:4

    Topics: Adult; Aged; Biomarkers, Tumor; Humans; Kaplan-Meier Estimate; Kynurenine; Logistic Models; Male; Mi

2017
High expression of indoleamine 2,3-dioxygenase gene in prostate cancer.
    European journal of cancer (Oxford, England : 1990), 2008, Volume: 44, Issue:15

    Topics: Aged; Aged, 80 and over; Cytokines; Gene Expression; Gene Expression Profiling; Humans; Immune Toler

2008
Indoleamine 2,3-dioxygenase (IDO) activity influence tumor growth in the TRAMP prostate cancer model.
    The Prostate, 2010, Sep-15, Volume: 70, Issue:13

    Topics: Adenocarcinoma; Animals; Blotting, Western; Disease Progression; Immunohistochemistry; Indoleamine-P

2010
Validation study of urinary metabolites as potential biomarkers for prostate cancer detection.
    Bioanalysis, 2012, Volume: 4, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Case-Control Studies; Chromatography,

2012
THE METABOLISM OF TRYPTOPHAN IN PATIENTS WITH BLADDER CANCER AND OTHER UROLOGICAL DISEASES.
    Clinica chimica acta; international journal of clinical chemistry, 1963, Volume: 8

    Topics: Geriatrics; Humans; Kidney Neoplasms; Kynurenic Acid; Kynurenine; Male; ortho-Aminobenzoates; Prosta

1963
The effect of tryptophan load and vitamin B 6 supplementation on urinary excretion of tryptophan metabolites in human male subjects.
    Clinical science, 1971, Volume: 41, Issue:3

    Topics: Aminohippuric Acids; Glucuronates; Humans; Kynurenine; Male; ortho-Aminobenzoates; Prostatic Hyperpl

1971
The role of some tryptophan metabolites in certain diseases of the genito-urinary system.
    British journal of urology, 1974, Volume: 46, Issue:3

    Topics: Chromatography, Thin Layer; Contraceptives, Oral; Female; Humans; Hydroxides; Hyperplasia; Kidney Ca

1974
The effect of estrogens on pyridoxal phosphate dependent enzymes in patients with cancer of the prostate.
    The Journal of urology, 1971, Volume: 105, Issue:3

    Topics: Alanine Transaminase; Aminohippuric Acids; Aspartate Aminotransferases; Carboxy-Lyases; Chlorotriani

1971