kynurenine has been researched along with Cancer of Pancreas in 13 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
Excerpt | Relevance | Reference |
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"In this study, a new mathematical model was established and validated to forecast and define sensitive targets in the kynurenine pathway (Kynp) in pancreatic adenocarcinoma (PDAC)." | 8.02 | Forecasting sensitive targets of the kynurenine pathway in pancreatic adenocarcinoma using mathematical modeling. ( Alahdal, M; Duan, L; Ouyang, H; Sun, D; Wang, D; Wang, M; Xiong, J, 2021) |
"Metabolomic profiling identified glucose and kynurenine to have potential clinical utility for differentiating mucinous from nonmucinous pancreatic cysts." | 7.79 | Metabolomic-derived novel cyst fluid biomarkers for pancreatic cysts: glucose and kynurenine. ( Banerjee, S; Bowen, R; Chen, AM; Fitch, WL; Friedland, S; Lowe, AW; Norton, JA; Pai, RK; Park, WG; Pasricha, PJ; Peltz, G; Poultsides, GA; Scott, BA; Visser, BC; Wodziak, D; Wu, M; Zheng, M, 2013) |
" Herein, we study the role of indoleamine 2,3-dioxygenase 1 (IDO1), an enzyme important in the conversion of tryptophan to kynurenine, in a murine model of pancreatic cancer-associated depression." | 4.12 | IDO1 Is a Therapeutic Target for Pancreatic Cancer-Associated Depression. ( Graor, HJ; Hajihassani, O; Hue, JJ; Ji, K; Katayama, ES; Loftus, AW; Vaziri-Gohar, A; Winter, JM; Zarei, M, 2022) |
"In this study, a new mathematical model was established and validated to forecast and define sensitive targets in the kynurenine pathway (Kynp) in pancreatic adenocarcinoma (PDAC)." | 4.02 | Forecasting sensitive targets of the kynurenine pathway in pancreatic adenocarcinoma using mathematical modeling. ( Alahdal, M; Duan, L; Ouyang, H; Sun, D; Wang, D; Wang, M; Xiong, J, 2021) |
"17 patients with pancreatic adenocarcinoma were recruited and completed mood questionnaires (Functional Assessment of Cancer Therapy -Pancreatic Cancer, Beck Depression Inventory and the Beck Anxiety Inventory) and blood testing for serum levels of tryptophan, kynurenine, kynurenic acid and quinolinic acid." | 3.80 | A biological basis for depression in pancreatic cancer. ( Botwinick, IC; Chabot, JA; Cooper, T; Mann, JJ; Pursell, L; Yu, G, 2014) |
"Metabolomic profiling identified glucose and kynurenine to have potential clinical utility for differentiating mucinous from nonmucinous pancreatic cysts." | 3.79 | Metabolomic-derived novel cyst fluid biomarkers for pancreatic cysts: glucose and kynurenine. ( Banerjee, S; Bowen, R; Chen, AM; Fitch, WL; Friedland, S; Lowe, AW; Norton, JA; Pai, RK; Park, WG; Pasricha, PJ; Peltz, G; Poultsides, GA; Scott, BA; Visser, BC; Wodziak, D; Wu, M; Zheng, M, 2013) |
"In the SUPPORT study, adult pancreatic cancer patients were randomized to intervention programs of 6-month (1) a Supervised moderate-to-high-intensity progressive resistance training or (2) unsupervised Home-based resistance training, or (3) to a standard care patient Control group." | 3.01 | Resistance Exercise Modulates Kynurenine Pathway in Pancreatic Cancer Patients. ( Clauss, D; Pal, A; Schmidt, ME; Steindorf, K; Ulrich, CM; Wiskemann, J; Zimmer, P, 2021) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (7.69) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 5 (38.46) | 24.3611 |
2020's | 7 (53.85) | 2.80 |
Authors | Studies |
---|---|
Liang, H | 1 |
Li, T | 1 |
Fang, X | 1 |
Xing, Z | 1 |
Zhang, S | 1 |
Shi, L | 1 |
Li, W | 1 |
Guo, L | 1 |
Kuang, C | 1 |
Liu, H | 1 |
Yang, Q | 1 |
Korac, K | 1 |
Rajasekaran, D | 1 |
Sniegowski, T | 1 |
Schniers, BK | 1 |
Ibrahim, AF | 1 |
Bhutia, YD | 2 |
Hue, JJ | 1 |
Graor, HJ | 1 |
Zarei, M | 1 |
Katayama, ES | 1 |
Ji, K | 1 |
Hajihassani, O | 1 |
Loftus, AW | 1 |
Vaziri-Gohar, A | 1 |
Winter, JM | 1 |
Yang, T | 1 |
Li, QQ | 1 |
Liu, YM | 1 |
Yang, B | 1 |
Jonescheit, H | 1 |
Oberg, HH | 1 |
Gonnermann, D | 1 |
Hermes, M | 1 |
Sulaj, V | 1 |
Peters, C | 1 |
Kabelitz, D | 1 |
Wesch, D | 1 |
Pal, A | 1 |
Zimmer, P | 1 |
Clauss, D | 1 |
Schmidt, ME | 1 |
Ulrich, CM | 1 |
Wiskemann, J | 1 |
Steindorf, K | 1 |
Alahdal, M | 1 |
Sun, D | 1 |
Duan, L | 1 |
Ouyang, H | 1 |
Wang, M | 1 |
Xiong, J | 1 |
Wang, D | 1 |
Ogura, J | 1 |
Miyauchi, S | 1 |
Shimono, K | 1 |
Yang, S | 1 |
Gonchigar, S | 1 |
Ganapathy, V | 1 |
Huang, JY | 1 |
Butler, LM | 1 |
Midttun, Ø | 1 |
Ulvik, A | 1 |
Wang, R | 1 |
Jin, A | 1 |
Gao, YT | 1 |
Ueland, PM | 1 |
Koh, WP | 1 |
Yuan, JM | 1 |
Leja-Szpak, A | 1 |
Góralska, M | 1 |
Link-Lenczowski, P | 1 |
Czech, U | 1 |
Nawrot-Porąbka, K | 1 |
Bonior, J | 1 |
Jaworek, J | 1 |
Park, WG | 1 |
Wu, M | 1 |
Bowen, R | 1 |
Zheng, M | 1 |
Fitch, WL | 1 |
Pai, RK | 1 |
Wodziak, D | 1 |
Visser, BC | 1 |
Poultsides, GA | 1 |
Norton, JA | 1 |
Banerjee, S | 1 |
Chen, AM | 1 |
Friedland, S | 1 |
Scott, BA | 1 |
Pasricha, PJ | 1 |
Lowe, AW | 1 |
Peltz, G | 1 |
Botwinick, IC | 1 |
Pursell, L | 1 |
Yu, G | 1 |
Cooper, T | 1 |
Mann, JJ | 1 |
Chabot, JA | 1 |
Ehrhart, H | 1 |
Ried, W | 1 |
Benoit, W | 1 |
Dörfler, H | 1 |
1 trial available for kynurenine and Cancer of Pancreas
Article | Year |
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Resistance Exercise Modulates Kynurenine Pathway in Pancreatic Cancer Patients.
Topics: Biomarkers; Disease Progression; Down-Regulation; Humans; Interleukin-6; Kynurenine; Metabolic Netwo | 2021 |
12 other studies available for kynurenine and Cancer of Pancreas
Article | Year |
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IDO1/TDO dual inhibitor RY103 targets Kyn-AhR pathway and exhibits preclinical efficacy on pancreatic cancer.
Topics: Animals; Cell Movement; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Gene Expressi | 2021 |
IDO1/TDO dual inhibitor RY103 targets Kyn-AhR pathway and exhibits preclinical efficacy on pancreatic cancer.
Topics: Animals; Cell Movement; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Gene Expressi | 2021 |
IDO1/TDO dual inhibitor RY103 targets Kyn-AhR pathway and exhibits preclinical efficacy on pancreatic cancer.
Topics: Animals; Cell Movement; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Gene Expressi | 2021 |
IDO1/TDO dual inhibitor RY103 targets Kyn-AhR pathway and exhibits preclinical efficacy on pancreatic cancer.
Topics: Animals; Cell Movement; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Gene Expressi | 2021 |
Carbidopa, an activator of aryl hydrocarbon receptor, suppresses IDO1 expression in pancreatic cancer and decreases tumor growth.
Topics: Animals; Carbidopa; Indoleamine-Pyrrole 2,3,-Dioxygenase; Janus Kinases; Kynurenine; Mice; Mice, Nud | 2022 |
Carbidopa, an activator of aryl hydrocarbon receptor, suppresses IDO1 expression in pancreatic cancer and decreases tumor growth.
Topics: Animals; Carbidopa; Indoleamine-Pyrrole 2,3,-Dioxygenase; Janus Kinases; Kynurenine; Mice; Mice, Nud | 2022 |
Carbidopa, an activator of aryl hydrocarbon receptor, suppresses IDO1 expression in pancreatic cancer and decreases tumor growth.
Topics: Animals; Carbidopa; Indoleamine-Pyrrole 2,3,-Dioxygenase; Janus Kinases; Kynurenine; Mice; Mice, Nud | 2022 |
Carbidopa, an activator of aryl hydrocarbon receptor, suppresses IDO1 expression in pancreatic cancer and decreases tumor growth.
Topics: Animals; Carbidopa; Indoleamine-Pyrrole 2,3,-Dioxygenase; Janus Kinases; Kynurenine; Mice; Mice, Nud | 2022 |
IDO1 Is a Therapeutic Target for Pancreatic Cancer-Associated Depression.
Topics: Animals; Depression; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Pancreatic Neoplasms; T | 2022 |
IDO1 Is a Therapeutic Target for Pancreatic Cancer-Associated Depression.
Topics: Animals; Depression; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Pancreatic Neoplasms; T | 2022 |
IDO1 Is a Therapeutic Target for Pancreatic Cancer-Associated Depression.
Topics: Animals; Depression; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Pancreatic Neoplasms; T | 2022 |
IDO1 Is a Therapeutic Target for Pancreatic Cancer-Associated Depression.
Topics: Animals; Depression; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Pancreatic Neoplasms; T | 2022 |
T cells in pancreatic cancer stroma: Tryptophan metabolism plays an important role in immunoregulation.
Topics: Animals; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Pancreatic Neoplasms; Th17 Cells; T | 2023 |
T cells in pancreatic cancer stroma: Tryptophan metabolism plays an important role in immunoregulation.
Topics: Animals; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Pancreatic Neoplasms; Th17 Cells; T | 2023 |
T cells in pancreatic cancer stroma: Tryptophan metabolism plays an important role in immunoregulation.
Topics: Animals; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Pancreatic Neoplasms; Th17 Cells; T | 2023 |
T cells in pancreatic cancer stroma: Tryptophan metabolism plays an important role in immunoregulation.
Topics: Animals; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Pancreatic Neoplasms; Th17 Cells; T | 2023 |
Influence of Indoleamine-2,3-Dioxygenase and Its Metabolite Kynurenine on γδ T Cell Cytotoxicity against Ductal Pancreatic Adenocarcinoma Cells.
Topics: Adenocarcinoma; Adult; Carcinoma, Pancreatic Ductal; Cell Communication; Cell Cycle Checkpoints; Cel | 2020 |
Forecasting sensitive targets of the kynurenine pathway in pancreatic adenocarcinoma using mathematical modeling.
Topics: Adenocarcinoma; Cell Line, Tumor; Humans; Kynurenine; Models, Theoretical; Pancreatic Neoplasms; Rep | 2021 |
Forecasting sensitive targets of the kynurenine pathway in pancreatic adenocarcinoma using mathematical modeling.
Topics: Adenocarcinoma; Cell Line, Tumor; Humans; Kynurenine; Models, Theoretical; Pancreatic Neoplasms; Rep | 2021 |
Forecasting sensitive targets of the kynurenine pathway in pancreatic adenocarcinoma using mathematical modeling.
Topics: Adenocarcinoma; Cell Line, Tumor; Humans; Kynurenine; Models, Theoretical; Pancreatic Neoplasms; Rep | 2021 |
Forecasting sensitive targets of the kynurenine pathway in pancreatic adenocarcinoma using mathematical modeling.
Topics: Adenocarcinoma; Cell Line, Tumor; Humans; Kynurenine; Models, Theoretical; Pancreatic Neoplasms; Rep | 2021 |
Carbidopa is an activator of aryl hydrocarbon receptor with potential for cancer therapy.
Topics: Active Transport, Cell Nucleus; Aryl Hydrocarbon Hydroxylases; Carbidopa; Cell Nucleus; Hep G2 Cells | 2017 |
A prospective evaluation of serum kynurenine metabolites and risk of pancreatic cancer.
Topics: 3-Hydroxyanthranilic Acid; Biomarkers; Case-Control Studies; China; Female; Humans; Kynurenine; Male | 2018 |
The Opposite Effect of L-kynurenine and Ahr Inhibitor Ch223191 on Apoptotic Protein Expression in Pancreatic Carcinoma Cells (Panc-1).
Topics: Antineoplastic Agents; Apoptosis; Azo Compounds; Cell Proliferation; Cell Survival; Dose-Response Re | 2019 |
The Opposite Effect of L-kynurenine and Ahr Inhibitor Ch223191 on Apoptotic Protein Expression in Pancreatic Carcinoma Cells (Panc-1).
Topics: Antineoplastic Agents; Apoptosis; Azo Compounds; Cell Proliferation; Cell Survival; Dose-Response Re | 2019 |
The Opposite Effect of L-kynurenine and Ahr Inhibitor Ch223191 on Apoptotic Protein Expression in Pancreatic Carcinoma Cells (Panc-1).
Topics: Antineoplastic Agents; Apoptosis; Azo Compounds; Cell Proliferation; Cell Survival; Dose-Response Re | 2019 |
The Opposite Effect of L-kynurenine and Ahr Inhibitor Ch223191 on Apoptotic Protein Expression in Pancreatic Carcinoma Cells (Panc-1).
Topics: Antineoplastic Agents; Apoptosis; Azo Compounds; Cell Proliferation; Cell Survival; Dose-Response Re | 2019 |
Metabolomic-derived novel cyst fluid biomarkers for pancreatic cysts: glucose and kynurenine.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Cohort Studies; Cys | 2013 |
A biological basis for depression in pancreatic cancer.
Topics: Adenocarcinoma; Affect; Aged; Aged, 80 and over; Depression; Female; Humans; Kynurenine; Lymphatic M | 2014 |
[Studies on experimental leukemias (VII). Adenocarcinomas, sarcomas and leukemias in mice following subcutaneous injections of 3-hydroxykynurenine].
Topics: Animals; Carcinogens; Carcinoma; Injections, Subcutaneous; Kynurenine; Leukemia, Experimental; Leuke | 1968 |