Page last updated: 2024-10-19

kynurenine and Blood Pressure, High

kynurenine has been researched along with Blood Pressure, High in 12 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Research Excerpts

ExcerptRelevanceReference
"Aim    To compare serum concentrations of tryptophane (Trp) and its metabolites in subjects with no cardiovascular disease (CVD) and patients with СVD, including arterial hypertension (AH) and ischemic heart disease (IHD)."8.12Comparative analysis of tryptophan and downstream metabolites of the kynurenine and serotonin pathways in patients with arterial hypertension and coronary artery disease. ( Ageev, AA; Appolonova, SA; Belenkov, YN; Korobkova, EO; Kozhevnikova, MV; Krivova, AV; Moskaleva, NE; Privalova, EV; Shestakova, KM, 2022)
"In symptomatic patients with severe aortic stenosis undergoing transcatheter aortic valve replacement, circulating levels of long-chain acylcarnitines were independently associated with measures of maladaptive LV remodeling, and metabolic perturbations lessened after procedure completion."7.88Association of Acylcarnitines With Left Ventricular Remodeling in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement. ( Elmariah, S; Farrell, LA; Furman, D; Gerszten, RE; Lindman, BR; Morningstar, JE; Rhee, EP; Shi, X, 2018)
" It was found that in a part of patients the long-term administration of antihypertensive drugs led to an increased accumulation of kynurenine as a manifestation of pyridoxal-5-phosphate deficiency."5.28Increased blood kynurenine level as a factor inhibiting the therapeutic effect of antihypertensive agents in combined long-term treatment of essential hypertension. ( Liepinja, DJ; Rudzite, VK; Silava, AK; Vitols, AV, 1990)
"Aim    To compare serum concentrations of tryptophane (Trp) and its metabolites in subjects with no cardiovascular disease (CVD) and patients with СVD, including arterial hypertension (AH) and ischemic heart disease (IHD)."4.12Comparative analysis of tryptophan and downstream metabolites of the kynurenine and serotonin pathways in patients with arterial hypertension and coronary artery disease. ( Ageev, AA; Appolonova, SA; Belenkov, YN; Korobkova, EO; Kozhevnikova, MV; Krivova, AV; Moskaleva, NE; Privalova, EV; Shestakova, KM, 2022)
"In symptomatic patients with severe aortic stenosis undergoing transcatheter aortic valve replacement, circulating levels of long-chain acylcarnitines were independently associated with measures of maladaptive LV remodeling, and metabolic perturbations lessened after procedure completion."3.88Association of Acylcarnitines With Left Ventricular Remodeling in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement. ( Elmariah, S; Farrell, LA; Furman, D; Gerszten, RE; Lindman, BR; Morningstar, JE; Rhee, EP; Shi, X, 2018)
" It was found that in a part of patients the long-term administration of antihypertensive drugs led to an increased accumulation of kynurenine as a manifestation of pyridoxal-5-phosphate deficiency."1.28Increased blood kynurenine level as a factor inhibiting the therapeutic effect of antihypertensive agents in combined long-term treatment of essential hypertension. ( Liepinja, DJ; Rudzite, VK; Silava, AK; Vitols, AV, 1990)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's3 (25.00)18.2507
2000's0 (0.00)29.6817
2010's4 (33.33)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
Dupont, V1
Berg, AH1
Yamashita, M1
Huang, C1
Covarrubias, AE1
Ali, S1
Stotland, A1
Van Eyk, JE1
Jim, B2
Thadhani, R1
Karumanchi, SA1
Kozhevnikova, MV2
Krivova, AV2
Korobkova, EO2
Ageev, AA2
Shestakova, KM2
Moskaleva, NE2
Appolonova, SA2
Privalova, EV2
Belenkov, YN2
Theiler-Schwetz, V1
Trummer, C1
Grübler, MR1
Keppel, MH1
Zittermann, A1
Tomaschitz, A1
März, W1
Meinitzer, A1
Pilz, S1
Gupta, S1
Petras, L1
Tufail, MU1
Rodriguez Salazar, JD1
Elmariah, S1
Farrell, LA1
Furman, D1
Lindman, BR1
Shi, X1
Morningstar, JE1
Rhee, EP1
Gerszten, RE1
Zhao, J2
Passos, CS1
Carvalho, LN1
Pontes, RB1
Campos, RR1
Ikuta, O1
Boim, MA1
Martinsons, A1
Rudzite, V2
Jurika, E1
Silava, A1
Sileniece, G1
Liepina, D1
Dalmane, A1
Zirne, R1
Rudzite, VK1
Vitols, AV1
Liepinja, DJ1
Silava, AK1
Rudzit, VK1
Silenietse, GO1
Zirne, RA1
Iurika, EV1

Reviews

1 review available for kynurenine and Blood Pressure, High

ArticleYear
Hypertension in Pregnancy: What We Now Know.
    Current opinion in nephrology and hypertension, 2023, Mar-01, Volume: 32, Issue:2

    Topics: Animals; Female; Fetus; Humans; Hypertension; Kynurenine; Mice; Pre-Eclampsia; Pregnancy

2023

Trials

1 trial available for kynurenine and Blood Pressure, High

ArticleYear
Plasma kynurenic acid/tryptophan ratio: a sensitive and reliable biomarker for the assessment of renal function.
    Renal failure, 2013, Volume: 35, Issue:5

    Topics: Adult; Aged; Chromatography, High Pressure Liquid; Female; Humans; Hypertension; Kidney Function Tes

2013

Other Studies

10 other studies available for kynurenine and Blood Pressure, High

ArticleYear
Impaired renal reserve contributes to preeclampsia via the kynurenine and soluble fms-like tyrosine kinase 1 pathway.
    The Journal of clinical investigation, 2022, 10-17, Volume: 132, Issue:20

    Topics: Animals; Female; Humans; Hypertension; Ischemia; Kidney; Kynurenine; Mice; Nephrectomy; Placenta; Pl

2022
Comparative analysis of tryptophan and downstream metabolites of the kynurenine and serotonin pathways in patients with arterial hypertension and coronary artery disease.
    Kardiologiia, 2022, Nov-30, Volume: 62, Issue:11

    Topics: Atherosclerosis; Coronary Artery Disease; Humans; Hydroxyindoleacetic Acid; Hypertension; Kynurenic

2022
Comparative analysis of tryptophan and downstream metabolites of the kynurenine and serotonin pathways in patients with arterial hypertension and coronary artery disease.
    Kardiologiia, 2022, Nov-30, Volume: 62, Issue:11

    Topics: Atherosclerosis; Coronary Artery Disease; Humans; Hydroxyindoleacetic Acid; Hypertension; Kynurenic

2022
Comparative analysis of tryptophan and downstream metabolites of the kynurenine and serotonin pathways in patients with arterial hypertension and coronary artery disease.
    Kardiologiia, 2022, Nov-30, Volume: 62, Issue:11

    Topics: Atherosclerosis; Coronary Artery Disease; Humans; Hydroxyindoleacetic Acid; Hypertension; Kynurenic

2022
Comparative analysis of tryptophan and downstream metabolites of the kynurenine and serotonin pathways in patients with arterial hypertension and coronary artery disease.
    Kardiologiia, 2022, Nov-30, Volume: 62, Issue:11

    Topics: Atherosclerosis; Coronary Artery Disease; Humans; Hydroxyindoleacetic Acid; Hypertension; Kynurenic

2022
Associations of Parameters of the Tryptophan-Kynurenine Pathway with Cardiovascular Risk Factors in Hypertensive Patients.
    Nutrients, 2023, Jan-04, Volume: 15, Issue:2

    Topics: Cardiovascular Diseases; Cross-Sectional Studies; Heart Disease Risk Factors; Humans; Hypertension;

2023
Association of Acylcarnitines With Left Ventricular Remodeling in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement.
    JAMA cardiology, 2018, 03-01, Volume: 3, Issue:3

    Topics: Aged, 80 and over; Aortic Valve Stenosis; Biomarkers; Carnitine; Choline; Diabetes Complications; Fe

2018
Simultaneous determination of plasma creatinine, uric acid, kynurenine and tryptophan by high-performance liquid chromatography: method validation and in application to the assessment of renal function.
    Biomedical chromatography : BMC, 2015, Volume: 29, Issue:3

    Topics: Adult; Aged; Chromatography, High Pressure Liquid; Creatinine; Female; Humans; Hypertension; Kidney

2015
Blood pressure reducing effects of Phalaris canariensis in normotensive and spontaneously hypertensive rats.
    Canadian journal of physiology and pharmacology, 2012, Volume: 90, Issue:2

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Dose-Response Relationship

2012
The relationship between kynurenine, catecholamines, and arterial hypertension in mesangioproliferative glomerulonephritis.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Blood Pressure; Catecholamines; Diastole; Dopamine; Epinephrine; Glomerulonephritis, Membranoprolife

1996
Impairment of kynurenine metabolism in cardiovascular disease.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Animals; Antihypertensive Agents; Cardiomyopathies; Cells, Cultured; Humans; Hypertension; Isoniazid

1991
Increased blood kynurenine level as a factor inhibiting the therapeutic effect of antihypertensive agents in combined long-term treatment of essential hypertension.
    Cor et vasa, 1990, Volume: 32, Issue:1

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiac Volume; Cardiomegaly; Clonidine; Drug Therap

1990
[Kynureninemia in patients with hypertension and ischemic heart disease previously treated with antitubercular drugs].
    Problemy tuberkuleza, 1988, Issue:7

    Topics: Antitubercular Agents; Coronary Disease; Humans; Hypertension; Kynurenine; Tuberculosis, Pulmonary

1988