kynurenine has been researched along with Bladder Cancer in 49 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate plasma and urinary kynurenine (KYN)-tryptophan (TRP) ratios in bladder cancer, expression of indoleamine 2,3-dioxygenase 1 (IDO1) in relation to tryptophan 2,3-dioxygenase (TDO2) in bladder tumour, and the correlation of KYN-TRP ratio with bladder tumour burden." | 8.02 | Tryptophan-kynurenine ratio as a biomarker of bladder cancer. ( Chan, ECY; Chen, KW; Chia, JY; Chiong, E; Chionh, BJ; Choo, SN; Esuvaranathan, K; Goh, BYS; Kioh, DYQ; Lee, SH; Lim, YX; Mahendran, R; Mallari, JZ; Periaswami, R; Raman, L; Tay, MHW; Tham, SM; Thamboo, TP; Tsang, WC; Wu, QH, 2021) |
| "Urinary excretion before and after a loading dose of tryptophan, plasma pyridoxal phosphate concentration and urinary excretion of 4-pyridoxic acid was studied in 44 male bladder cancer patients from Copenhagen." | 7.66 | Tryptophan metabolism in bladder cancer patients from Copenhagen. ( Brown, RR; Wolf, H, 1979) |
| "Tryptophan metabolism was studied in a family in which a sister and brother had bladder cancer." | 7.65 | Abnormal tryptophan metabolism in a family with a history of bladder cancer. ( Brown, RR; Leklem, JE, 1976) |
| "Urinary excretion of metabolites of the kynurenine pathway before and after a loading dose of 2 g L-tryptophan was studied in 31 bladder cancer patients from the Copenhagen area." | 7.65 | Studies on tryptophan metabolism in Danish bladder cancer patients. ( Brown, RR; Nyholm, K; Wolf, H, 1975) |
| "In tryptophan metabolites, 3-hydroxykynurenine and 3-hydroxyanthranilic acid have been reported to show a carcinogenic action to mice bladder and the relation of the metabolites to human bladder cancer has been discussed." | 4.79 | [Microanalysis of tryptophan metabolites]. ( Watanabe, M, 1997) |
| "To investigate plasma and urinary kynurenine (KYN)-tryptophan (TRP) ratios in bladder cancer, expression of indoleamine 2,3-dioxygenase 1 (IDO1) in relation to tryptophan 2,3-dioxygenase (TDO2) in bladder tumour, and the correlation of KYN-TRP ratio with bladder tumour burden." | 4.02 | Tryptophan-kynurenine ratio as a biomarker of bladder cancer. ( Chan, ECY; Chen, KW; Chia, JY; Chiong, E; Chionh, BJ; Choo, SN; Esuvaranathan, K; Goh, BYS; Kioh, DYQ; Lee, SH; Lim, YX; Mahendran, R; Mallari, JZ; Periaswami, R; Raman, L; Tay, MHW; Tham, SM; Thamboo, TP; Tsang, WC; Wu, QH, 2021) |
| "In 100 patients suffering from urinary bladder cancer (pTA-4, Nx, M0-1, G0-3) we created an oral tryptophan load administering 5 g of L-type tryptophan." | 3.67 | [Studies of tryptophan metabolism in cancer of the urinary bladder]. ( Grimm, U; Knapp, A; Wich, H, 1989) |
| "Urinary excretion of six aromatic amine metabolites of tryptophan was compared between a group of 30 patients with bladder cancer and a group of 33 controls selected from the general population of the study area." | 3.66 | Urinary tryptophan metabolites and cancer of the bladder in humans. ( Friedlander, E; Morrison, AS, 1981) |
| "Urinary excretion before and after a loading dose of tryptophan, plasma pyridoxal phosphate concentration and urinary excretion of 4-pyridoxic acid was studied in 44 male bladder cancer patients from Copenhagen." | 3.66 | Tryptophan metabolism in bladder cancer patients from Copenhagen. ( Brown, RR; Wolf, H, 1979) |
| "Tryptophan metabolism was studied in a family in which a sister and brother had bladder cancer." | 3.65 | Abnormal tryptophan metabolism in a family with a history of bladder cancer. ( Brown, RR; Leklem, JE, 1976) |
| "Urinary excretion of metabolites of the kynurenine pathway before and after a loading dose of 2 g L-tryptophan was studied in 31 bladder cancer patients from the Copenhagen area." | 3.65 | Studies on tryptophan metabolism in Danish bladder cancer patients. ( Brown, RR; Nyholm, K; Wolf, H, 1975) |
| "They produced bladder cancer when implanted in the bladder." | 2.47 | Possible roles of excess tryptophan metabolites in cancer. ( Chung, KT; Gadupudi, GS, 2011) |
| "Advanced Bladder Cancer (BLCA) remains a clinical challenge that lacks effective therapeutic measures." | 1.56 | Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression. ( Arnold, JM; Bader, DA; Cao, Q; Coarfa, C; Devarakonda, V; Donepudi, SR; Dubrulle, J; Jain, AK; Karanam, B; Kavuri, SM; Lotan, Y; Ma, J; Maity, S; McGuire, SE; Putluri, N; Putluri, V; Rajapakshe, K; Sikora, AG; Sreekumar, A; Stossi, F; Vantaku, V; Villanueva, H; von Rundstedt, FC, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (83.67) | 18.7374 |
| 1990's | 2 (4.08) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (4.08) | 24.3611 |
| 2020's | 4 (8.16) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, SH | 2 |
| Mahendran, R | 2 |
| Tham, SM | 2 |
| Thamboo, TP | 2 |
| Kioh, DYQ | 2 |
| Tang, LWT | 1 |
| Chiong, E | 2 |
| Esuvaranathan, K | 2 |
| Chan, ECY | 2 |
| Chionh, BJ | 1 |
| Lim, YX | 1 |
| Tsang, WC | 1 |
| Wu, QH | 1 |
| Chia, JY | 1 |
| Tay, MHW | 1 |
| Goh, BYS | 1 |
| Chen, KW | 1 |
| Mallari, JZ | 1 |
| Periaswami, R | 1 |
| Raman, L | 1 |
| Choo, SN | 1 |
| Matheus, LHG | 1 |
| Dalmazzo, SV | 1 |
| Brito, RBO | 1 |
| Pereira, LA | 1 |
| de Almeida, RJ | 1 |
| Camacho, CP | 1 |
| Dellê, H | 1 |
| Vantaku, V | 1 |
| Putluri, V | 1 |
| Bader, DA | 1 |
| Maity, S | 1 |
| Ma, J | 1 |
| Arnold, JM | 1 |
| Rajapakshe, K | 1 |
| Donepudi, SR | 1 |
| von Rundstedt, FC | 1 |
| Devarakonda, V | 1 |
| Dubrulle, J | 1 |
| Karanam, B | 1 |
| McGuire, SE | 1 |
| Stossi, F | 1 |
| Jain, AK | 1 |
| Coarfa, C | 1 |
| Cao, Q | 1 |
| Sikora, AG | 1 |
| Villanueva, H | 1 |
| Kavuri, SM | 1 |
| Lotan, Y | 1 |
| Sreekumar, A | 1 |
| Putluri, N | 1 |
| Chung, KT | 1 |
| Gadupudi, GS | 1 |
| Gamagedara, S | 1 |
| Kaczmarek, AT | 1 |
| Jiang, Y | 1 |
| Cheng, X | 2 |
| Rupasinghe, M | 1 |
| Ma, Y | 1 |
| QUAGLIARIELLO, E | 2 |
| AURICCHIO, S | 1 |
| CASALE, M | 1 |
| TANCREDI, F | 2 |
| FEDELE, L | 1 |
| WALLACE, DM | 1 |
| WHITE, RW | 1 |
| BENASSI, CA | 1 |
| PERISSINOTTO, B | 1 |
| ALLEGRI, G | 1 |
| BRYAN, GT | 4 |
| BROWN, RR | 13 |
| MORRIS, CR | 2 |
| PRICE, JM | 4 |
| KHALAFALLAH, AS | 1 |
| ABUL-FADL, MA | 1 |
| Schlegel, JU | 2 |
| Pipkin, G | 1 |
| Banowsky, L | 1 |
| Friedlander, E | 1 |
| Morrison, AS | 1 |
| Newling, DW | 1 |
| Robinson, MR | 1 |
| Smith, PH | 1 |
| Byar, D | 1 |
| Lockwood, R | 1 |
| Stevens, I | 1 |
| De Pauw, M | 1 |
| Sylvester, R | 1 |
| Watanabe, M | 1 |
| Wolf, H | 5 |
| Teulings, FA | 2 |
| Peters, HA | 2 |
| Hop, WC | 1 |
| Fokkens, W | 2 |
| Haije, WG | 1 |
| Portengen, H | 1 |
| van der Werf-Messing, B | 2 |
| Matsushima, M | 1 |
| Leklem, JE | 3 |
| Romas, NA | 1 |
| Ionascu, L | 1 |
| Sholem, S | 1 |
| Ionescu, G | 1 |
| Veenema, RJ | 1 |
| Mulder-Kooy, GE | 1 |
| Nyholm, K | 1 |
| Wich, H | 1 |
| Grimm, U | 1 |
| Knapp, A | 1 |
| Abdel-Tawab, GA | 4 |
| Aboul-Azm, T | 1 |
| Ebied, SA | 1 |
| el-Toukhy, MA | 1 |
| Abdel-Hamied, HA | 1 |
| el-Kholy, ZA | 1 |
| el-Sharaky, AS | 1 |
| Byrne, GI | 1 |
| Lehmann, LK | 1 |
| Kirschbaum, JG | 1 |
| Borden, EC | 1 |
| Lee, CM | 1 |
| Grabstald, H | 1 |
| Linker, DG | 1 |
| Beattie, EJ | 1 |
| Watson, RC | 1 |
| Lieberman, PH | 1 |
| Melamed, MR | 1 |
| Ehrhart, H | 2 |
| Ried, W | 1 |
| Benoit, W | 1 |
| Dörfler, H | 1 |
| Woodford, J | 1 |
| Rose, DP | 1 |
| Kochen, W | 1 |
| Hochberg, K | 1 |
| Burney, SW | 1 |
| Friedell, GH | 1 |
| Hankes, LV | 1 |
| Schmaeler, M | 1 |
| Schievelbein, H | 1 |
| Kuntze, I | 1 |
| Gailani, S | 1 |
| Murphy, G | 1 |
| Kenny, G | 1 |
| Nussbaum, A | 1 |
| Silvernail, P | 1 |
| Al-Hadithi, NA | 1 |
| Martynenko, AG | 1 |
| Kartasheva, LA | 1 |
| Goĭkhberg, MI | 1 |
| Klimenko, IA | 1 |
| Abdel-Daim, MH | 2 |
| el-Sewedy, SM | 1 |
| Kelada, FS | 1 |
| DeGeorge, FV | 1 |
| Amer, MS | 1 |
| Musajo, L | 1 |
| Ibrahim, EK | 1 |
| el-Masri, A | 1 |
| al-Ghorab, M | 1 |
| Makhyoun, N | 1 |
| Pipkin, GE | 1 |
| Nishimura, R | 1 |
| Duke, GA | 1 |
3 reviews available for kynurenine and Bladder Cancer
| Article | Year |
|---|---|
Possible roles of excess tryptophan metabolites in cancer.
Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; DNA Damage; Dogs; Humans; Kynurenine; Liver N | 2011 |
[Microanalysis of tryptophan metabolites].
Topics: 3-Hydroxyanthranilic Acid; Animals; Fluorometry; Humans; Kynurenic Acid; Kynurenine; Mice; Microchem | 1997 |
The role of urinary tryptophan metabolites in the etiology of bladder cancer.
Topics: Alcohols; Amino Acids; Animals; Carcinogens; Ethers; Female; Humans; Indican; Kynurenic Acid; Kynure | 1971 |
1 trial available for kynurenine and Bladder Cancer
| Article | Year |
|---|---|
Tryptophan metabolites, pyridoxine (vitamin B6) and their influence on the recurrence rate of superficial bladder cancer. Results of a prospective, randomised phase III study performed by the EORTC GU Group. EORTC Genito-Urinary Tract Cancer Cooperative G
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Transitional | 1995 |
45 other studies available for kynurenine and Bladder Cancer
| Article | Year |
|---|---|
Combination Bacillus Calmette-Guérin and indoleamine 2,3-dioxygenase 1 inhibitor therapy of murine orthotopic bladder cancer.
Topics: Acetamides; Animals; Antineoplastic Agents; BCG Vaccine; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynur | 2020 |
Tryptophan-kynurenine ratio as a biomarker of bladder cancer.
Topics: Aged; Biomarkers, Tumor; Case-Control Studies; Correlation of Data; Female; Humans; Kynurenine; Male | 2021 |
1-Methyl-D-tryptophan activates aryl hydrocarbon receptor, a pathway associated with bladder cancer progression.
Topics: Aged; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Cytochrome P-450 CYP1A1; Cytoc | 2020 |
Epigenetic loss of AOX1 expression via EZH2 leads to metabolic deregulations and promotes bladder cancer progression.
Topics: Aldehyde Oxidase; Animals; Cell Line, Tumor; Disease Progression; Enhancer of Zeste Homolog 2 Protei | 2020 |
Validation study of urinary metabolites as potential biomarkers for prostate cancer detection.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Case-Control Studies; Chromatography, | 2012 |
[Certain metabolic peculiarities observed in individuals with tumors of the bladder; preventive note].
Topics: Aminobenzoates; Humans; Kynurenine; Neoplasms; Urinary Bladder Neoplasms | 1958 |
[Possibility of diagnosis of tumors of the bladder by chromatographic revelation of metabolites of the tryptophan-nicotinic acid interrelation].
Topics: Humans; Kynurenine; Niacin; ortho-Aminobenzoates; Tryptophan; Urinary Bladder Neoplasms; Urine | 1960 |
BIOCHEMICAL ASPECTS OF BLADDER TUMOURS.
Topics: Glucuronidase; Humans; Kynurenine; ortho-Aminobenzoates; Sulfatases; Urinary Bladder Neoplasms; Urin | 1963 |
THE METABOLISM OF TRYPTOPHAN IN PATIENTS WITH BLADDER CANCER AND OTHER UROLOGICAL DISEASES.
Topics: Geriatrics; Humans; Kidney Neoplasms; Kynurenic Acid; Kynurenine; Male; ortho-Aminobenzoates; Prosta | 1963 |
IN VIVO ELUTION OF TRYPTOPHAN METABOLITES AND OTHER AROMATIC NITROGEN COMPOUNDS FROM CHOLESTEROL PELLETS IMPLANTED INTO MOUSE BLADDERS.
Topics: Amines; Animals; Carcinogens; Cholesterol; Fluorenes; Hydroxylamines; Kynurenic Acid; Kynurenine; Me | 1964 |
MOUSE BLADDER CARCINOGENICITY OF CERTAIN TRYPTOPHAN METABOLITES AND OTHER AROMATIC NITROGEN COMPOUNDS SUSPENDED IN CHOLESTEROL.
Topics: Amines; Animals; Carcinogens; Cholesterol; Fluorenes; Hydroxylamines; Kynurenic Acid; Kynurenine; Me | 1964 |
STUDIES ON THE URINARY EXCRETION OF CERTAIN TRYPTOPHAN METABOLITES BEFORE AND AFTER TRYPTOPHAN LOADING DOSE IN BILHARZIASIS, BILHARZIAL BLADDER CANCER AND CERTAIN OTHER TYPES OF MALIGNANCIES IN EGYPT.
Topics: Amino Acids; Egypt; Epidemiology; Fluids and Secretions; Humans; Hydroxyindoleacetic Acid; Indoleace | 1964 |
Urine composition in the etiology of bladder tumor formation.
Topics: Carcinogens; Humans; Kynurenic Acid; Kynurenine; ortho-Aminobenzoates; Tryptophan; Urinary Bladder N | 1967 |
Urinary tryptophan metabolites and cancer of the bladder in humans.
Topics: Adult; Age Factors; Aged; Aminohippuric Acids; Female; Humans; Kynurenine; Male; Middle Aged; ortho- | 1981 |
Tryptophan metabolism in bladder cancer patients from Copenhagen.
Topics: Denmark; Humans; Kynurenine; Male; Pyridoxal Phosphate; Pyridoxic Acid; Tryptophan; Urinary Bladder | 1979 |
A new aspect of the urinary excretion of tryptophan metabolites in patients with cancer of the bladder.
Topics: 3-Hydroxyanthranilic Acid; Adult; Aged; Aspartate Aminotransferases; Creatinine; Female; Humans; Kid | 1978 |
[The role of L-tryptophan's promoting factor on tumorgenesis in the urinary bladder. 1. A study on the urinary tryptophan metabolites (author's transl)].
Topics: Adolescent; Adult; Aged; Female; Humans; Kynurenine; Male; Middle Aged; Tryptophan; Urinary Bladder | 1977 |
Abnormal tryptophan metabolism in a family with a history of bladder cancer.
Topics: Aged; Female; Humans; Kynurenine; Male; Metabolism, Inborn Errors; Middle Aged; Pyridoxine; Tryptoph | 1976 |
A new method for determination of urinary tryptophan metabolites in bladder carcinoma.
Topics: 3-Hydroxyanthranilic Acid; Chromatography, Thin Layer; Female; Humans; Kynurenic Acid; Kynurenine; M | 1975 |
The excretion of 3-hydroxyanthranilic acid in patients with bladder and kidney carcinoma.
Topics: 3-Hydroxyanthranilic Acid; Female; Humans; Kidney Neoplasms; Kynurenine; Male; ortho-Aminobenzoates; | 1975 |
Studies on tryptophan metabolism in Danish bladder cancer patients.
Topics: Denmark; Humans; Kynurenine; Male; Tryptophan; Urinary Bladder Neoplasms | 1975 |
[Studies of tryptophan metabolism in cancer of the urinary bladder].
Topics: Humans; Kynurenine; Risk Factors; Tryptophan; Urinary Bladder Neoplasms; Xanthurenates | 1989 |
The correlation between certain tryptophan metabolites and the N-nitrosamine content in the urine of bilharzial bladder cancer patients.
Topics: 3-Hydroxyanthranilic Acid; Adult; Aminohippuric Acids; Colorimetry; Humans; Indican; Kynurenic Acid; | 1986 |
Induction of tryptophan degradation in vitro and in vivo: a gamma-interferon-stimulated activity.
Topics: Carcinoma; Cells, Cultured; Fibroblasts; Humans; Interferon beta-1a; Interferon beta-1b; Interferon | 1986 |
The effect of tryptophan load and vitamin B 6 supplementation on urinary excretion of tryptophan metabolites in human male subjects.
Topics: Aminohippuric Acids; Glucuronates; Humans; Kynurenine; Male; ortho-Aminobenzoates; Prostatic Hyperpl | 1971 |
Multicentric and multifocal urothelial tumors.
Topics: Acetophenones; Aged; Aniline Compounds; Carcinogens; Glucuronidase; Humans; Hydronephrosis; Kynureni | 1974 |
[Studies on experimental leukemias (VII). Adenocarcinomas, sarcomas and leukemias in mice following subcutaneous injections of 3-hydroxykynurenine].
Topics: Animals; Carcinogens; Carcinoma; Injections, Subcutaneous; Kynurenine; Leukemia, Experimental; Leuke | 1968 |
Comparative tryptophan metabolism in cats and rats: differences in adaptation of tryptophan oxygenase and in vivo metabolism of tryptophan, kynurenine and hydroxykynurenine.
Topics: Amino Acids; Aminohippuric Acids; Animals; Cats; Enzyme Induction; Glucuronates; Hydrocortisone; Ind | 1969 |
Tryptophan metabolism as affected by anovulatory agents.
Topics: Aminohippuric Acids; Chlorotrianisene; Diethylstilbestrol; Estrogens; Female; Humans; Isoniazid; Kyn | 1969 |
[Tryptophan metabolism in bladder carcinoma].
Topics: Aged; Animals; Autoradiography; Carcinoma; Chromatography; Humans; Kynurenic Acid; Kynurenine; Middl | 1970 |
Lack of effect of smoking on the excretion of tryptophan metabolites by man.
Topics: Adult; Aminohippuric Acids; Female; Glucuronates; Humans; Kynurenic Acid; Kynurenine; Male; Middle A | 1970 |
Tryptophan metabolism in the cat: a study with carbon-14-labeled compounds.
Topics: Aminohippuric Acids; Animals; Carbon Dioxide; Carbon Isotopes; Cat Diseases; Cats; Kynurenine; Male; | 1971 |
[Proceedings: Tryptophan metabolism, bladder carcinoma and smoking habits].
Topics: 3-Hydroxyanthranilic Acid; Carcinoma; Humans; Kynurenine; Niacinamide; Smoking; Tryptophan; Urinary | 1972 |
Studies on the role of tryptophan metabolites in the genesis of bladder cancer.
Topics: Animals; Carbon Isotopes; Cholesterol; Feces; Female; Humans; Kynurenine; Mice; Mononuclear Phagocyt | 1973 |
[Proceedings: Endogenous carcinogens. Experimental induction of malignant tumors and leukemias by the tryptophan metabolites 3-hydroxyanthranilic acid and 3-hydroxykynurenine].
Topics: 3-Hydroxyanthranilic Acid; Animals; Carcinoma; Kynurenine; Leukemia, Experimental; Lung Neoplasms; M | 1972 |
Studies on tryptophen metabolism in patients with bladder cancer.
Topics: Humans; Hydrolases; Kynurenine; Liver; Neoplasm Metastasis; Papilloma; Time Factors; Tryptophan; Try | 1973 |
The role of some tryptophan metabolites in certain diseases of the genito-urinary system.
Topics: Chromatography, Thin Layer; Contraceptives, Oral; Female; Humans; Hydroxides; Hyperplasia; Kidney Ca | 1974 |
[Disorders of tryptophan metabolism in bladder neoplasms].
Topics: Female; Humans; Kynurenine; Male; Methionine; Nicotinic Acids; ortho-Aminobenzoates; Pyridoxine; Sea | 1972 |
In vivo effect of tartar emetic on tryptophan metabolism in patients with schistosomiasis.
Topics: Adolescent; Adult; Child; Humans; Hydrolases; Kynurenine; Pyridoxine; Schistosomiasis; Tartrates; Tr | 1969 |
Differences in tryptophan metabolism between breast cancer patients with and without cancer at other sites.
Topics: Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Female; Humans; Kynurenic Acid; Kynurenine; Lung | 1970 |
Studies with tryptophan metabolites in vitro. Kynurenine metabolism in kidneys of mice infested with Schistosoma mansoni.
Topics: Animals; Hydrolases; In Vitro Techniques; Kidney; Kynurenic Acid; Kynurenine; Mice; ortho-Aminobenzo | 1968 |
Some new aspects of tryptophan degradation.
Topics: Adult; Age Factors; Chromatography; Female; Humans; Kynurenine; Male; Pregnancy; Sex Factors; Trypto | 1968 |
Studies on tryptophan metabolism in bilharzial bladder cancer patients.
Topics: Adult; Humans; Kynurenine; Male; Occupational Diseases; ortho-Aminobenzoates; Schistosomiasis; Trypt | 1968 |
Studies in the etiology and prevention of bladder carcinoma.
Topics: Ascorbic Acid; Carcinogens; Free Radicals; Humans; Kynurenine; Luminescent Measurements; ortho-Amino | 1968 |
Absorption of 14 C-labeled 3-hydroxy-L-kynurenine and 3-hydroxyanthranilic acid from the mouse urinary bladder under carcinogenic conditions.
Topics: Animals; Carbon Dioxide; Carbon Isotopes; Carcinogens; Cats; Feces; Female; In Vitro Techniques; Kid | 1965 |