kynurenine has been researched along with Autism Spectrum Disorder in 9 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
Autism Spectrum Disorder: Wide continuum of associated cognitive and neurobehavioral disorders, including, but not limited to, three core-defining features: impairments in socialization, impairments in verbal and nonverbal communication, and restricted and repetitive patterns of behaviors. (from DSM-V)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Increasing literature highlighted alterations of tryptophan (TRP) metabolism and kynurenine (KYN) pathway in children with autism spectrum disorder (ASD)." | 8.31 | Kynurenine pathway and autism spectrum phenotypes: an investigation among adults with autism spectrum disorder and their first-degree relatives. ( Betti, L; Carmassi, C; Carpita, B; Cremone, IM; Dell'Osso, L; Giannaccini, G; Massimetti, G; Nardi, B; Palego, L, 2023) |
| "There are increasing reports about the potential role of kynurenine pathway metabolites in autism spectrum disorder (ASD)." | 8.12 | Altered kynurenine pathway metabolite levels in toddlers and preschool children with autism spectrum disorder. ( Abuşoğlu, S; Akça, ÖF; Baysal, T; Bilgiç, A; Oflaz, MB; Sadıç Çelikkol, Ç; Sivrikaya, A; Ünlü, A, 2022) |
| "The kynurenine pathway (KP) is a major route of the essential amino acid L-tryptophan (Trp) catabolism in mammalian cells." | 7.01 | Maternal Inflammation with Elevated Kynurenine Metabolites Is Related to the Risk of Abnormal Brain Development and Behavioral Changes in Autism Spectrum Disorder. ( Fang, K; Imamura, Y; Kasahara, Y; Konishi, Y; Momono, Y; Murakami, Y; Nishiyama, T; Sakai, D; Yoshida, C, 2023) |
| "Increasing literature highlighted alterations of tryptophan (TRP) metabolism and kynurenine (KYN) pathway in children with autism spectrum disorder (ASD)." | 4.31 | Kynurenine pathway and autism spectrum phenotypes: an investigation among adults with autism spectrum disorder and their first-degree relatives. ( Betti, L; Carmassi, C; Carpita, B; Cremone, IM; Dell'Osso, L; Giannaccini, G; Massimetti, G; Nardi, B; Palego, L, 2023) |
| "There are increasing reports about the potential role of kynurenine pathway metabolites in autism spectrum disorder (ASD)." | 4.12 | Altered kynurenine pathway metabolite levels in toddlers and preschool children with autism spectrum disorder. ( Abuşoğlu, S; Akça, ÖF; Baysal, T; Bilgiç, A; Oflaz, MB; Sadıç Çelikkol, Ç; Sivrikaya, A; Ünlü, A, 2022) |
| "To quantify the full range of tryptophan metabolites along the kynurenine pathway, a liquid chromatography - tandem mass spectrometry method was developed and used to analyse brain extracts of rodents treated with the kynurenine-3-mono-oxygenase (KMO) inhibitor Ro61-8048 during pregnancy." | 3.83 | Kynurenine pathway metabolism following prenatal KMO inhibition and in Mecp2 ( Cobb, SR; Dalton, RN; Darlington, LG; Forrest, CM; Kennedy, PG; Rodgers, J; Stone, TW; Turner, C, 2016) |
| "The kynurenine pathway (KP) is a major route of the essential amino acid L-tryptophan (Trp) catabolism in mammalian cells." | 3.01 | Maternal Inflammation with Elevated Kynurenine Metabolites Is Related to the Risk of Abnormal Brain Development and Behavioral Changes in Autism Spectrum Disorder. ( Fang, K; Imamura, Y; Kasahara, Y; Konishi, Y; Momono, Y; Murakami, Y; Nishiyama, T; Sakai, D; Yoshida, C, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 5 (55.56) | 2.80 |
| Authors | Studies |
|---|---|
| Tanaka, M | 1 |
| Spekker, E | 1 |
| Szabó, Á | 1 |
| Polyák, H | 1 |
| Vécsei, L | 1 |
| Carpita, B | 1 |
| Nardi, B | 1 |
| Palego, L | 1 |
| Cremone, IM | 1 |
| Massimetti, G | 1 |
| Carmassi, C | 1 |
| Betti, L | 1 |
| Giannaccini, G | 1 |
| Dell'Osso, L | 1 |
| Murakami, Y | 2 |
| Imamura, Y | 2 |
| Kasahara, Y | 1 |
| Yoshida, C | 1 |
| Momono, Y | 1 |
| Fang, K | 1 |
| Sakai, D | 2 |
| Konishi, Y | 1 |
| Nishiyama, T | 1 |
| Yildirim, V | 1 |
| Simsek, S | 1 |
| Cetin, I | 1 |
| Dokuyucu, R | 1 |
| Saito, K | 1 |
| Motoyama, J | 1 |
| Bilgiç, A | 1 |
| Abuşoğlu, S | 1 |
| Sadıç Çelikkol, Ç | 1 |
| Oflaz, MB | 1 |
| Akça, ÖF | 1 |
| Sivrikaya, A | 1 |
| Baysal, T | 1 |
| Ünlü, A | 1 |
| Bryn, V | 2 |
| Verkerk, R | 2 |
| Skjeldal, OH | 2 |
| Saugstad, OD | 2 |
| Ormstad, H | 2 |
| Halvorsen, B | 1 |
| Isaksen, J | 1 |
| Maes, M | 1 |
| Forrest, CM | 1 |
| Kennedy, PG | 1 |
| Rodgers, J | 1 |
| Dalton, RN | 1 |
| Turner, C | 1 |
| Darlington, LG | 1 |
| Cobb, SR | 1 |
| Stone, TW | 1 |
2 reviews available for kynurenine and Autism Spectrum Disorder
| Article | Year |
|---|---|
Modelling the neurodevelopmental pathogenesis in neuropsychiatric disorders. Bioactive kynurenines and their analogues as neuroprotective agents-in celebration of 80th birthday of Professor Peter Riederer.
Topics: Animals; Autism Spectrum Disorder; Humans; Kynurenine; Neurodevelopmental Disorders; Neuroprotective | 2022 |
Maternal Inflammation with Elevated Kynurenine Metabolites Is Related to the Risk of Abnormal Brain Development and Behavioral Changes in Autism Spectrum Disorder.
Topics: Animals; Autism Spectrum Disorder; Brain; Female; Inflammation; Kynurenine; Mammals; Pregnancy; Tryp | 2023 |
7 other studies available for kynurenine and Autism Spectrum Disorder
| Article | Year |
|---|---|
Kynurenine pathway and autism spectrum phenotypes: an investigation among adults with autism spectrum disorder and their first-degree relatives.
Topics: Autism Spectrum Disorder; Autistic Disorder; Humans; Kynurenic Acid; Kynurenine; Phenotype; Tryptoph | 2023 |
Kynurenine, Kynurenic Acid, Quinolinic Acid and Interleukin-6 Levels in the Serum of Patients with Autism Spectrum Disorder.
Topics: Autism Spectrum Disorder; Child; Child, Preschool; Humans; Infant; Interleukin-6; Kynurenic Acid; Ky | 2023 |
Altered kynurenine pathway metabolites in a mouse model of human attention-deficit hyperactivity/autism spectrum disorders: A potential new biological diagnostic marker.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Brain; Disease Mod | 2019 |
Altered kynurenine pathway metabolite levels in toddlers and preschool children with autism spectrum disorder.
Topics: Autism Spectrum Disorder; Child, Preschool; Humans; Infant; Kynurenic Acid; Kynurenine; Tandem Mass | 2022 |
Kynurenine Pathway in Autism Spectrum Disorders in Children.
Topics: Autism Spectrum Disorder; Biomarkers; Child; Chromatography, High Pressure Liquid; Comorbidity; Fema | 2017 |
Serum Tryptophan, Tryptophan Catabolites and Brain-derived Neurotrophic Factor in Subgroups of Youngsters with Autism Spectrum Disorders.
Topics: 5-Hydroxytryptophan; Adolescent; Analysis of Variance; Autism Spectrum Disorder; Brain-Derived Neuro | 2018 |
Kynurenine pathway metabolism following prenatal KMO inhibition and in Mecp2
Topics: Animals; Autism Spectrum Disorder; Brain; Chromatography, Liquid; Female; Kynurenic Acid; Kynurenine | 2016 |