kynurenine has been researched along with Aspergillosis in 2 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
Aspergillosis: Infections with fungi of the genus ASPERGILLUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we show that a superoxide-dependent step in tryptophan metabolism along the kynurenine pathway is blocked in CGD mice with lethal pulmonary aspergillosis, leading to unrestrained Vgamma1(+) gammadelta T-cell reactivity, dominant production of interleukin (IL)-17, defective regulatory T-cell activity and acute inflammatory lung injury." | 7.74 | Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease. ( Bistoni, F; D'Angelo, C; De Luca, A; Fallarino, F; Fioretti, MC; Grohmann, U; Montagnoli, C; Puccetti, P; Romani, L; Segal, BH; Vacca, C; Zelante, T, 2008) |
| " Here we show that a superoxide-dependent step in tryptophan metabolism along the kynurenine pathway is blocked in CGD mice with lethal pulmonary aspergillosis, leading to unrestrained Vgamma1(+) gammadelta T-cell reactivity, dominant production of interleukin (IL)-17, defective regulatory T-cell activity and acute inflammatory lung injury." | 3.74 | Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease. ( Bistoni, F; D'Angelo, C; De Luca, A; Fallarino, F; Fioretti, MC; Grohmann, U; Montagnoli, C; Puccetti, P; Romani, L; Segal, BH; Vacca, C; Zelante, T, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zelante, T | 2 |
| De Luca, A | 2 |
| D'Angelo, C | 2 |
| Moretti, S | 1 |
| Romani, L | 2 |
| Fallarino, F | 1 |
| Montagnoli, C | 1 |
| Vacca, C | 1 |
| Bistoni, F | 1 |
| Fioretti, MC | 1 |
| Grohmann, U | 1 |
| Segal, BH | 1 |
| Puccetti, P | 1 |
2 other studies available for kynurenine and Aspergillosis
| Article | Year |
|---|---|
IL-17/Th17 in anti-fungal immunity: what's new?
Topics: Animals; Aspergillosis; Candidiasis; Cytokines; Humans; Immunity, Innate; Indoleamine-Pyrrole 2,3,-D | 2009 |
Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.
Topics: Animals; Aspergillosis; Aspergillus fumigatus; Chronic Disease; Disease Models, Animal; Granulomatou | 2008 |