kynurenine has been researched along with Arteriosclerosis, Coronary in 12 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aim To compare serum concentrations of tryptophane (Trp) and its metabolites in subjects with no cardiovascular disease (CVD) and patients with СVD, including arterial hypertension (AH) and ischemic heart disease (IHD)." | 8.12 | Comparative analysis of tryptophan and downstream metabolites of the kynurenine and serotonin pathways in patients with arterial hypertension and coronary artery disease. ( Ageev, AA; Appolonova, SA; Belenkov, YN; Korobkova, EO; Kozhevnikova, MV; Krivova, AV; Moskaleva, NE; Privalova, EV; Shestakova, KM, 2022) |
| "Metabolites of the kynurenine pathway (mKP) relate to important aspects of heart failure pathophysiology, such as inflammation, energy-homeostasis, apoptosis, and oxidative stress." | 7.96 | Plasma kynurenines and prognosis in patients with heart failure. ( Giil, LM; Lund, A; Midttun, Ø; Nordrehaug, JE; Nygård, O; Pedersen, EK; Slettom, G; Solvang, SH; Ueland, PM; Ulvik, A, 2020) |
| " We assessed downstream tryptophan metabolites of the kynurenine pathway as predictors of acute myocardial infarction in patients with suspected stable angina pectoris." | 7.81 | Associations of plasma kynurenines with risk of acute myocardial infarction in patients with stable angina pectoris. ( Eussen, SJ; Mellgren, G; Meyer, K; Midttun, Ø; Nilsen, DW; Nordrehaug, JE; Nygård, O; Pedersen, ER; Strand, E; Svingen, GF; Tuseth, N; Ueland, PM; Ulvik, A, 2015) |
| "contribute to the development of coronary atherosclerosis and subsequent coronary artery disease." | 6.72 | Kynurenine Pathway Metabolites as Potential Clinical Biomarkers in Coronary Artery Disease. ( Berkecz, R; Csont, T; Demján, V; Gáspár, R; Halmi, D; Pipicz, M, 2021) |
| "Aim To compare serum concentrations of tryptophane (Trp) and its metabolites in subjects with no cardiovascular disease (CVD) and patients with СVD, including arterial hypertension (AH) and ischemic heart disease (IHD)." | 4.12 | Comparative analysis of tryptophan and downstream metabolites of the kynurenine and serotonin pathways in patients with arterial hypertension and coronary artery disease. ( Ageev, AA; Appolonova, SA; Belenkov, YN; Korobkova, EO; Kozhevnikova, MV; Krivova, AV; Moskaleva, NE; Privalova, EV; Shestakova, KM, 2022) |
| "Metabolites of the kynurenine pathway (mKP) relate to important aspects of heart failure pathophysiology, such as inflammation, energy-homeostasis, apoptosis, and oxidative stress." | 3.96 | Plasma kynurenines and prognosis in patients with heart failure. ( Giil, LM; Lund, A; Midttun, Ø; Nordrehaug, JE; Nygård, O; Pedersen, EK; Slettom, G; Solvang, SH; Ueland, PM; Ulvik, A, 2020) |
| " We assessed downstream tryptophan metabolites of the kynurenine pathway as predictors of acute myocardial infarction in patients with suspected stable angina pectoris." | 3.81 | Associations of plasma kynurenines with risk of acute myocardial infarction in patients with stable angina pectoris. ( Eussen, SJ; Mellgren, G; Meyer, K; Midttun, Ø; Nilsen, DW; Nordrehaug, JE; Nygård, O; Pedersen, ER; Strand, E; Svingen, GF; Tuseth, N; Ueland, PM; Ulvik, A, 2015) |
| "In patients with stable angina pectoris, systemic markers of IFN-γ activity, plasma neopterin, and plasma KTR provide similar risk estimates for MCE and mortality." | 3.77 | Systemic markers of interferon-γ-mediated immune activation and long-term prognosis in patients with stable coronary artery disease. ( Berge, R; Bleie, Ø; Ebbing, M; Igland, J; Midttun, Ø; Nordrehaug, JE; Nygård, O; Pedersen, ER; Schartum-Hansen, H; Seifert, R; Svingen, G; Ueland, PM, 2011) |
| "An increase in immune-stimulated synthesis of kynurenine from tryptophan by indoleamine 2,3-dioxygenase (IDO) has been observed in patients with coronary artery disease (CAD)." | 3.75 | Indoleamine 2,3-dioxygenase activation and depressive symptoms in patients with coronary artery disease. ( Dowlati, Y; Herrmann, N; Kiss, A; Lanctôt, KL; Oh, PI; Swardfager, W; Walker, SE, 2009) |
| "contribute to the development of coronary atherosclerosis and subsequent coronary artery disease." | 2.72 | Kynurenine Pathway Metabolites as Potential Clinical Biomarkers in Coronary Artery Disease. ( Berkecz, R; Csont, T; Demján, V; Gáspár, R; Halmi, D; Pipicz, M, 2021) |
| "Kynurenine is a potent endothelium-derived vasodilator." | 1.39 | Urinary excretion of kynurenine and tryptophan, cardiovascular events, and mortality after elective coronary angiography. ( Ebbing, M; Igland, J; Nilsen, RM; Nordrehaug, JE; Nygård, O; Pedersen, ER; Schartum-Hansen, H; Seifert, R; Svingen, GF; Ueland, PM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 8 (66.67) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gáspár, R | 1 |
| Halmi, D | 1 |
| Demján, V | 1 |
| Berkecz, R | 1 |
| Pipicz, M | 1 |
| Csont, T | 1 |
| Kozhevnikova, MV | 2 |
| Krivova, AV | 2 |
| Korobkova, EO | 2 |
| Ageev, AA | 2 |
| Shestakova, KM | 2 |
| Moskaleva, NE | 2 |
| Appolonova, SA | 2 |
| Privalova, EV | 2 |
| Belenkov, YN | 2 |
| Lund, A | 1 |
| Nordrehaug, JE | 4 |
| Slettom, G | 1 |
| Solvang, SH | 1 |
| Pedersen, EK | 1 |
| Midttun, Ø | 6 |
| Ulvik, A | 2 |
| Ueland, PM | 8 |
| Nygård, O | 7 |
| Giil, LM | 1 |
| Rebnord, EW | 1 |
| Strand, E | 3 |
| Svingen, GFT | 1 |
| Christensen, MHE | 1 |
| Mellgren, G | 2 |
| Njølstad, PR | 1 |
| Tell, GS | 2 |
| Nygård, OK | 1 |
| Pedersen, ER | 6 |
| Svingen, GF | 2 |
| Schartum-Hansen, H | 2 |
| Ebbing, M | 2 |
| Igland, J | 2 |
| Seifert, R | 2 |
| Nilsen, RM | 1 |
| Midttun, O | 1 |
| Townsend, MK | 1 |
| Tworoger, SS | 1 |
| Brennan, P | 1 |
| Johansson, M | 1 |
| Ozkan, Y | 1 |
| Sukuroglu, MK | 1 |
| Tulmac, M | 1 |
| Kisa, U | 1 |
| Simsek, B | 1 |
| Tuseth, N | 1 |
| Eussen, SJ | 2 |
| Meyer, K | 1 |
| Nilsen, DW | 1 |
| Karlsson, T | 1 |
| Dierkes, J | 1 |
| Drevon, CA | 1 |
| Øyen, J | 1 |
| Gudbrandsen, OA | 1 |
| Swardfager, W | 1 |
| Herrmann, N | 1 |
| Dowlati, Y | 1 |
| Oh, PI | 1 |
| Kiss, A | 1 |
| Walker, SE | 1 |
| Lanctôt, KL | 1 |
| Svingen, G | 1 |
| Bleie, Ø | 1 |
| Berge, R | 1 |
| Sulo, G | 1 |
| Vollset, SE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomised Double Blind Study of the Effects of Homocysteine Lowering Therapy on Mortality and Cardiac Events in Patients Undergoing Coronary Angiography[NCT00354081] | Phase 3 | 3,096 participants (Actual) | Interventional | 1999-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for kynurenine and Arteriosclerosis, Coronary
| Article | Year |
|---|---|
Kynurenine Pathway Metabolites as Potential Clinical Biomarkers in Coronary Artery Disease.
Topics: Biomarkers; Coronary Artery Disease; Humans; Inflammation; Kynurenine; Tryptophan | 2021 |
1 trial available for kynurenine and Arteriosclerosis, Coronary
| Article | Year |
|---|---|
Most blood biomarkers related to vitamin status, one-carbon metabolism, and the kynurenine pathway show adequate preanalytical stability and within-person reproducibility to allow assessment of exposure or nutritional status in healthy women and cardiovas
Topics: Adult; Aged; Biomarkers; Blood Specimen Collection; Carbon; Chemistry, Clinical; Coronary Artery Dis | 2014 |
10 other studies available for kynurenine and Arteriosclerosis, Coronary
| Article | Year |
|---|---|
Comparative analysis of tryptophan and downstream metabolites of the kynurenine and serotonin pathways in patients with arterial hypertension and coronary artery disease.
Topics: Atherosclerosis; Coronary Artery Disease; Humans; Hydroxyindoleacetic Acid; Hypertension; Kynurenic | 2022 |
Comparative analysis of tryptophan and downstream metabolites of the kynurenine and serotonin pathways in patients with arterial hypertension and coronary artery disease.
Topics: Atherosclerosis; Coronary Artery Disease; Humans; Hydroxyindoleacetic Acid; Hypertension; Kynurenic | 2022 |
Comparative analysis of tryptophan and downstream metabolites of the kynurenine and serotonin pathways in patients with arterial hypertension and coronary artery disease.
Topics: Atherosclerosis; Coronary Artery Disease; Humans; Hydroxyindoleacetic Acid; Hypertension; Kynurenic | 2022 |
Comparative analysis of tryptophan and downstream metabolites of the kynurenine and serotonin pathways in patients with arterial hypertension and coronary artery disease.
Topics: Atherosclerosis; Coronary Artery Disease; Humans; Hydroxyindoleacetic Acid; Hypertension; Kynurenic | 2022 |
Plasma kynurenines and prognosis in patients with heart failure.
Topics: Aged; Biomarkers; Case-Control Studies; Coronary Artery Disease; Female; Heart Failure; Humans; Kynu | 2020 |
The kynurenine:tryptophan ratio as a predictor of incident type 2 diabetes mellitus in individuals with coronary artery disease.
Topics: Aged; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Humans; Kynurenine; Male; Middle A | 2017 |
Urinary excretion of kynurenine and tryptophan, cardiovascular events, and mortality after elective coronary angiography.
Topics: Coronary Angiography; Coronary Artery Disease; Female; Humans; Kynurenine; Male; Middle Aged; Myocar | 2013 |
Relation of kynurenine/tryptophan with immune and inflammatory markers in coronary artery disease.
Topics: Aged; Biomarkers; Chromatography, High Pressure Liquid; Coronary Artery Disease; Enzyme-Linked Immun | 2014 |
Associations of plasma kynurenines with risk of acute myocardial infarction in patients with stable angina pectoris.
Topics: Aged; Angina, Stable; Biomarkers; Coronary Angiography; Coronary Artery Disease; Diabetes Mellitus, | 2015 |
Associations between intake of fish and n-3 long-chain polyunsaturated fatty acids and plasma metabolites related to the kynurenine pathway in patients with coronary artery disease.
Topics: 3-Hydroxyanthranilic Acid; Aged; Animals; Biomarkers; Body Mass Index; Cholesterol; Coronary Artery | 2017 |
Indoleamine 2,3-dioxygenase activation and depressive symptoms in patients with coronary artery disease.
Topics: Coronary Artery Disease; Depression; Enzyme Activation; Female; Humans; Indoleamine-Pyrrole 2,3,-Dio | 2009 |
Systemic markers of interferon-γ-mediated immune activation and long-term prognosis in patients with stable coronary artery disease.
Topics: Aged; Angina Pectoris; Biomarkers; C-Reactive Protein; Coronary Angiography; Coronary Artery Disease | 2011 |
Neopterin and kynurenine-tryptophan ratio as predictors of coronary events in older adults, the Hordaland Health Study.
Topics: Aged; Biomarkers; Coronary Artery Disease; Female; Follow-Up Studies; Health Surveys; Humans; Kynure | 2013 |