kynurenine has been researched along with Anhedonia in 9 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
Anhedonia: Inability to experience pleasure due to impairment or dysfunction of normal psychological and neurobiological mechanisms. It is a symptom of many PSYCHOTIC DISORDERS (e.g., DEPRESSIVE DISORDER, MAJOR; and SCHIZOPHRENIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Geriatric depression is a costly health issue, but little is known about its physiological underpinnings." | 1.39 | Aging leads to prolonged duration of inflammation-induced depression-like behavior caused by Bacillus Calmette-Guérin. ( Dantzer, R; Kelley, KW; Lawson, MA; McCusker, RH; O'Connor, JC; Rodriguez-Zas, SL, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (88.89) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Orrico-Sanchez, A | 1 |
| Guiard, BP | 1 |
| Manta, S | 1 |
| Callebert, J | 1 |
| Launay, JM | 1 |
| Louis, F | 1 |
| Paccard, A | 1 |
| Gruszczynski, C | 1 |
| Betancur, C | 1 |
| Vialou, V | 1 |
| Gautron, S | 1 |
| DeWitt, SJ | 1 |
| Bradley, KA | 2 |
| Lin, N | 1 |
| Yu, C | 1 |
| Gabbay, V | 3 |
| de Gomes, MG | 1 |
| Souza, LC | 1 |
| Goes, AR | 1 |
| Del Fabbro, L | 1 |
| Filho, CB | 1 |
| Donato, F | 1 |
| Prigol, M | 1 |
| Luchese, C | 1 |
| Roman, SS | 1 |
| Puntel, RL | 1 |
| Boeira, SP | 1 |
| Jesse, CR | 1 |
| Kelley, KW | 1 |
| O'Connor, JC | 1 |
| Lawson, MA | 1 |
| Dantzer, R | 3 |
| Rodriguez-Zas, SL | 1 |
| McCusker, RH | 1 |
| Savitz, J | 2 |
| Drevets, WC | 2 |
| Smith, CM | 1 |
| Victor, TA | 2 |
| Wurfel, BE | 2 |
| Bellgowan, PS | 1 |
| Bodurka, J | 2 |
| Teague, TK | 2 |
| Case, JA | 1 |
| Khan, O | 1 |
| Ricart, T | 1 |
| Hanna, A | 1 |
| Alonso, CM | 1 |
| Meier, TB | 1 |
| McIntosh, SA | 1 |
| Ford, BN | 1 |
| Morris, HM | 1 |
| Barat, P | 1 |
| Meiffred, MC | 1 |
| Brossaud, J | 1 |
| Fuchs, D | 1 |
| Corcuff, JB | 1 |
| Thibault, H | 1 |
| Capuron, L | 1 |
| Ely, BA | 1 |
| Babb, J | 1 |
| Liebes, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Longitudinal Study of Inflammatory Pathways in Depression[NCT04159207] | 160 participants (Anticipated) | Observational | 2019-10-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for kynurenine and Anhedonia
| Article | Year |
|---|---|
Organic cation transporter 2 contributes to SSRI antidepressant efficacy by controlling tryptophan availability in the brain.
Topics: Anhedonia; Animals; Antidepressive Agents; Brain; Corticosterone; Depressive Disorder, Major; Fluoxe | 2023 |
A pilot resting-state functional connectivity study of the kynurenine pathway in adolescents with depression and healthy controls.
Topics: Adolescent; Anhedonia; Brain; Case-Control Studies; Depressive Disorder, Major; Female; Gray Matter; | 2018 |
Fish oil ameliorates sickness behavior induced by lipopolysaccharide in aged mice through the modulation of kynurenine pathway.
Topics: Aging; Anhedonia; Animals; Behavior, Animal; Biomarkers; Body Weight; Brain; Cytokines; Fish Oils; I | 2018 |
Aging leads to prolonged duration of inflammation-induced depression-like behavior caused by Bacillus Calmette-Guérin.
Topics: Aging; Anhedonia; Animals; Behavior, Animal; Body Weight; Chronic Disease; Depression; Hindlimb Susp | 2013 |
Putative neuroprotective and neurotoxic kynurenine pathway metabolites are associated with hippocampal and amygdalar volumes in subjects with major depressive disorder.
Topics: Adult; Amygdala; Anhedonia; Brain-Derived Neurotrophic Factor; C-Reactive Protein; Depressive Disord | 2015 |
The role of the kynurenine pathway in suicidality in adolescent major depressive disorder.
Topics: Adolescent; Anhedonia; Biomarkers; Depressive Disorder, Major; Female; Humans; Kynurenine; Male; Sui | 2015 |
Activation of the kynurenine pathway is associated with striatal volume in major depressive disorder.
Topics: Adult; Anhedonia; Biomarkers; Corpus Striatum; Depressive Disorder, Major; Female; Humans; Kynurenic | 2015 |
Inflammatory, endocrine and metabolic correlates of fatigue in obese children.
Topics: Adolescent; Anhedonia; Apathy; Body Mass Index; C-Reactive Protein; Child; Fatigue; Female; Humans; | 2016 |
The possible role of the kynurenine pathway in anhedonia in adolescents.
Topics: Adolescent; Anhedonia; Biomarkers; Depressive Disorder, Major; Female; Humans; Kynurenine; Male; Neu | 2012 |