kynurenine has been researched along with Amino Acid Metabolism Disorders, Inborn in 17 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We propose urinary levels of 3-hydroxykynurenine/3-hydroxyanthranilic acid to be surrogate indicators for predicting the adverse effects of D-tryptophan from the break point of body-weight gains and urinary levels of D-tryptophan metabolites." | 3.80 | The urinary ratio of 3-hydroxykynurenine/3-hydroxyanthranilic acid is an index to predicting the adverse effects of D-tryptophan in rats. ( Fukuwatari, T; Ohno, T; Sano, M; Shibata, K, 2014) |
| "Glutaric aciduria type I is an inborn error of organic acid metabolism that demonstrates a particular temporal vulnerability (acute encephalopathic episodes in infancy) and a spatial vulnerability (acute striatal necrosis, focused on the putamen)." | 2.42 | Glutaric aciduria type I and kynurenine pathway metabolites: a modified hypothesis. ( Surtees, R; Varadkar, S, 2004) |
| "Quinolinic acid (QUIN) is an agonist of the neurotransmitter glutamate (Glu) capable of binding to N-methyl-D-aspartate receptors (NMDAR) increasing glutamatergic signaling." | 1.62 | Caenorhabditis elegans as a model for studies on quinolinic acid-induced NMDAR-dependent glutamatergic disorders. ( Antunes Soares, FA; Aschner, M; Bicca Obetine Baptista, F; Duarte Hartmann, D; Farina Gonçalves, D; Franzen da Silva, A; Lenz Dalla Corte, C; Limana da Silveira, T; Lopes Machado, M; Marafiga Cordeiro, L, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (64.71) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 1 (5.88) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Limana da Silveira, T | 1 |
| Lopes Machado, M | 1 |
| Bicca Obetine Baptista, F | 1 |
| Farina Gonçalves, D | 1 |
| Duarte Hartmann, D | 1 |
| Marafiga Cordeiro, L | 1 |
| Franzen da Silva, A | 1 |
| Lenz Dalla Corte, C | 1 |
| Aschner, M | 1 |
| Antunes Soares, FA | 1 |
| Shibata, K | 1 |
| Ohno, T | 1 |
| Sano, M | 1 |
| Fukuwatari, T | 1 |
| KOMROWER, GM | 2 |
| WILSON, V | 1 |
| CLAMP, JR | 1 |
| WESTALL, RG | 1 |
| MICHAEL, AF | 1 |
| DRUMMOND, KN | 1 |
| DOEDEN, D | 1 |
| ANDERSON, JA | 1 |
| GOOD, RA | 1 |
| Varadkar, S | 1 |
| Surtees, R | 1 |
| Westall, R | 1 |
| Jyothy, A | 1 |
| Reddy, PP | 1 |
| Imai, J | 1 |
| Yoshida, I | 1 |
| Murayama, K | 1 |
| Sakai, Y | 1 |
| Shimizu, H | 1 |
| Sumi, T | 1 |
| Iguchi, T | 1 |
| Kawai, M | 1 |
| Yamaguchi, S | 1 |
| Ohura, T | 1 |
| Sewell, AC | 1 |
| Herwig, J | 1 |
| Böhles, H | 1 |
| Abeling, NG | 1 |
| van Gennip, AH | 1 |
| Smirnova, GP | 1 |
| Kamyshev, NG | 1 |
| Ponomarenko, VV | 1 |
| Grimm, U | 2 |
| Knapp, A | 2 |
| Schmitz, W | 2 |
| Smetan, M | 2 |
| Schmitz, KW | 2 |
| Reddemann, H | 2 |
| Schulz, M | 2 |
| Schlenzka, K | 2 |
| Reddi, OS | 1 |
| Reddy, MV | 1 |
| Reddy, KR | 1 |
| Machill, G | 1 |
| Binazzi, M | 1 |
| Calandra, P | 1 |
| Tabolin, VA | 1 |
| Kruglov, BV | 1 |
| Lebedev, VP | 1 |
| Levitina, NO | 1 |
| Price, JM | 1 |
4 reviews available for kynurenine and Amino Acid Metabolism Disorders, Inborn
| Article | Year |
|---|---|
Glutaric aciduria type I and kynurenine pathway metabolites: a modified hypothesis.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Glutarates; Humans; Kynurenine; Phenotype | 2004 |
[Kynureninase deficiency].
Topics: Amino Acid Metabolism, Inborn Errors; Diagnosis, Differential; Humans; Hydrolases; Kynurenine; Progn | 1998 |
[Chief clinical syndromes in children with tryptophan metabolism disorders (literature survey)].
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Carboxy-Lyases; Child; Child, Preschool; Diabetes | 1972 |
Factors which alter the metabolism of tryptophan.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Contraceptives, Oral; Female; Humans; Kynurenine; Nic | 1968 |
13 other studies available for kynurenine and Amino Acid Metabolism Disorders, Inborn
| Article | Year |
|---|---|
Caenorhabditis elegans as a model for studies on quinolinic acid-induced NMDAR-dependent glutamatergic disorders.
Topics: 1-Octanol; Adenosine Triphosphate; Amino Acid Metabolism, Inborn Errors; Animals; Animals, Genetical | 2021 |
The urinary ratio of 3-hydroxykynurenine/3-hydroxyanthranilic acid is an index to predicting the adverse effects of D-tryptophan in rats.
Topics: 3-Hydroxyanthranilic Acid; Amino Acid Metabolism, Inborn Errors; Animals; Diet; Hydrolases; Kynureni | 2014 |
HYDROXYKYNURENINURIA: A CASE OF ABNORMAL TRYPTOPHAN METABOLISM PROBABLY DUE TO A DEFICIENCY OF KYNURENINASE.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Chromatography; Electrophoresis; Humans; Hydrolases; Ky | 1964 |
TRYPTOPHAN METABOLISM IN MAN.
Topics: Amino Acid Metabolism, Inborn Errors; Calcium; Child; Glucuronates; Humans; Indican; Indoleacetic Ac | 1964 |
Hydroxykynureninuria.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Female; Growth; Humans; Infant, Newborn; Intellige | 1967 |
Screening for aminoacid disorders in mental retardation.
Topics: Alkaptonuria; Amino Acid Metabolism, Inborn Errors; Child, Preschool; Female; Humans; Infant; Intell | 1984 |
Determination of the 8-methyl ether of xanthurenic acid in human serum by high-performance liquid chromatography with fluorescence detection.
Topics: Amino Acid Metabolism, Inborn Errors; Chromatography, High Pressure Liquid; Ethers; Humans; Kynureni | 1996 |
Normal kynurenine metabolism in 2-oxoadipic aciduria.
Topics: Adipates; Amino Acid Metabolism, Inborn Errors; Female; Humans; Infant; Kynurenine | 1999 |
[Motor activity of tryptophan--xanthommatin metabolic pathway mutants in Drosophila melanogaster].
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Disease Models, Animal; Drosophila melanogaster; Kynu | 1979 |
[Tryptophan metabolism and oligophrenia (author's transl)].
Topics: Amino Acid Metabolism, Inborn Errors; Down Syndrome; Epilepsy; Hartnup Disease; Humans; Intellectual | 1978 |
Familial hydroxykynureninuria.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Consanguinity; Female; Gingival Diseases; Humans; Intel | 1978 |
[Determination of kynureninase activity in oligophrenic children with hereditary taint, before and after vitamin B6 treatment].
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Child; Humans; Hydrolases; Intellectual Dis | 1975 |
Tryptophan metabolsim and serum fatty acids in acrodermatitis enteropathica.
Topics: Acrodermatitis; Adolescent; Amino Acid Metabolism, Inborn Errors; Aminohippuric Acids; Arachidonic A | 1974 |