kynurenine has been researched along with Allodynia in 7 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Migraine and neuropathic pain are common causes of chronic pain." | 2.52 | Drug targets of migraine and neuropathy: treatment of hyperexcitability. ( Balog, A; Majláth, Z; Tajti, J; Vécsei, L, 2015) |
| "OBJECTIVE: Neuropathic pain is regulated by several metabolites of the kynurenine pathway (KYNA-kynurenic acid, and QA-quinolinic acid)." | 1.91 | Nociceptive improvements and kynurenine pathway alterations with diclofenac treatment in a rat model of neuropathic pain created by partial sciatic nerve ligation. ( Debbag, S; Saricaoglu, F; Yalcinkaya, A, 2023) |
| "Chronic pain was evaluated by thermal hyperalgesia in Hargreaves test and mechanical allodynia in von Frey test, depressive-like behaviors were evaluated by immobility time in forced swim test and tail suspension test." | 1.48 | Chronic trans-astaxanthin treatment exerts antihyperalgesic effect and corrects co-morbid depressive like behaviors in mice with chronic pain. ( Ding, L; Jiang, X; Jing, C; Liu, F; Pang, C; Yan, Q; Zhang, L, 2018) |
| "l-Kynurenine has antinociceptive effects in acute and inflammatory pain." | 1.39 | The L-kynurenine-probenecid combination reduces neuropathic pain in rats. ( Aguilera, P; Barragán-Iglesias, P; Bravo-Hernández, M; Cervantes-Durán, C; González-Esquivel, DF; Granados-Soto, V; Pérez-Severiano, F; Pineda-Farias, JB; Ríos, C, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Debbag, S | 1 |
| Yalcinkaya, A | 1 |
| Saricaoglu, F | 1 |
| Yaksh, TL | 1 |
| Schwarcz, R | 1 |
| Snodgrass, HR | 1 |
| Jiang, X | 1 |
| Yan, Q | 1 |
| Liu, F | 1 |
| Jing, C | 1 |
| Ding, L | 1 |
| Zhang, L | 1 |
| Pang, C | 1 |
| Pineda-Farias, JB | 1 |
| Pérez-Severiano, F | 1 |
| González-Esquivel, DF | 1 |
| Barragán-Iglesias, P | 1 |
| Bravo-Hernández, M | 1 |
| Cervantes-Durán, C | 1 |
| Aguilera, P | 1 |
| Ríos, C | 1 |
| Granados-Soto, V | 1 |
| Vécsei, L | 1 |
| Majláth, Z | 1 |
| Balog, A | 1 |
| Tajti, J | 1 |
| Huang, L | 1 |
| Ou, R | 1 |
| Rabelo de Souza, G | 1 |
| Cunha, TM | 1 |
| Lemos, H | 1 |
| Mohamed, E | 1 |
| Li, L | 1 |
| Pacholczyk, G | 1 |
| Randall, J | 1 |
| Munn, DH | 1 |
| Mellor, AL | 1 |
| Zhang, GF | 1 |
| Wang, J | 1 |
| Han, JF | 1 |
| Guo, J | 1 |
| Xie, ZM | 1 |
| Pan, W | 1 |
| Yang, JJ | 1 |
| Sun, KJ | 1 |
1 review available for kynurenine and Allodynia
| Article | Year |
|---|---|
Drug targets of migraine and neuropathy: treatment of hyperexcitability.
Topics: Animals; Excitatory Amino Acid Agents; Glutamic Acid; Humans; Hyperalgesia; Kynurenine; Migraine Dis | 2015 |
6 other studies available for kynurenine and Allodynia
| Article | Year |
|---|---|
Nociceptive improvements and kynurenine pathway alterations with diclofenac treatment in a rat model of neuropathic pain created by partial sciatic nerve ligation.
Topics: Animals; Diclofenac; Hyperalgesia; Kynurenine; Neuralgia; Nociception; Rats; Rats, Sprague-Dawley; S | 2023 |
Characterization of the Effects of L-4-Chlorokynurenine on Nociception in Rodents.
Topics: Amines; Analgesics; Animals; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dizocilpine | 2017 |
Chronic trans-astaxanthin treatment exerts antihyperalgesic effect and corrects co-morbid depressive like behaviors in mice with chronic pain.
Topics: Analgesics; Animals; Behavior, Animal; Chronic Pain; Cytokines; Depression; Hydroxyindoleacetic Acid | 2018 |
The L-kynurenine-probenecid combination reduces neuropathic pain in rats.
Topics: Animals; Drug Therapy, Combination; Female; Hyperalgesia; Kynurenine; Motor Activity; Neuralgia; Pai | 2013 |
Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase.
Topics: Animals; Disease Models, Animal; Flow Cytometry; Hyperalgesia; Indoleamine-Pyrrole 2,3,-Dioxygenase; | 2016 |
Acute single dose of ketamine relieves mechanical allodynia and consequent depression-like behaviors in a rat model.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Freund's Adjuv | 2016 |