Page last updated: 2024-10-19

kynurenine and Allodynia

kynurenine has been researched along with Allodynia in 7 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Research Excerpts

ExcerptRelevanceReference
"Migraine and neuropathic pain are common causes of chronic pain."2.52Drug targets of migraine and neuropathy: treatment of hyperexcitability. ( Balog, A; Majláth, Z; Tajti, J; Vécsei, L, 2015)
"OBJECTIVE: Neuropathic pain is regulated by several metabolites of the kynurenine pathway (KYNA-kynurenic acid, and QA-quinolinic acid)."1.91Nociceptive improvements and kynurenine pathway alterations with diclofenac treatment in a rat model of neuropathic pain created by partial sciatic nerve ligation. ( Debbag, S; Saricaoglu, F; Yalcinkaya, A, 2023)
"Chronic pain was evaluated by thermal hyperalgesia in Hargreaves test and mechanical allodynia in von Frey test, depressive-like behaviors were evaluated by immobility time in forced swim test and tail suspension test."1.48Chronic trans-astaxanthin treatment exerts antihyperalgesic effect and corrects co-morbid depressive like behaviors in mice with chronic pain. ( Ding, L; Jiang, X; Jing, C; Liu, F; Pang, C; Yan, Q; Zhang, L, 2018)
"l-Kynurenine has antinociceptive effects in acute and inflammatory pain."1.39The L-kynurenine-probenecid combination reduces neuropathic pain in rats. ( Aguilera, P; Barragán-Iglesias, P; Bravo-Hernández, M; Cervantes-Durán, C; González-Esquivel, DF; Granados-Soto, V; Pérez-Severiano, F; Pineda-Farias, JB; Ríos, C, 2013)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (85.71)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Debbag, S1
Yalcinkaya, A1
Saricaoglu, F1
Yaksh, TL1
Schwarcz, R1
Snodgrass, HR1
Jiang, X1
Yan, Q1
Liu, F1
Jing, C1
Ding, L1
Zhang, L1
Pang, C1
Pineda-Farias, JB1
Pérez-Severiano, F1
González-Esquivel, DF1
Barragán-Iglesias, P1
Bravo-Hernández, M1
Cervantes-Durán, C1
Aguilera, P1
Ríos, C1
Granados-Soto, V1
Vécsei, L1
Majláth, Z1
Balog, A1
Tajti, J1
Huang, L1
Ou, R1
Rabelo de Souza, G1
Cunha, TM1
Lemos, H1
Mohamed, E1
Li, L1
Pacholczyk, G1
Randall, J1
Munn, DH1
Mellor, AL1
Zhang, GF1
Wang, J1
Han, JF1
Guo, J1
Xie, ZM1
Pan, W1
Yang, JJ1
Sun, KJ1

Reviews

1 review available for kynurenine and Allodynia

ArticleYear
Drug targets of migraine and neuropathy: treatment of hyperexcitability.
    CNS & neurological disorders drug targets, 2015, Volume: 14, Issue:5

    Topics: Animals; Excitatory Amino Acid Agents; Glutamic Acid; Humans; Hyperalgesia; Kynurenine; Migraine Dis

2015

Other Studies

6 other studies available for kynurenine and Allodynia

ArticleYear
Nociceptive improvements and kynurenine pathway alterations with diclofenac treatment in a rat model of neuropathic pain created by partial sciatic nerve ligation.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:9

    Topics: Animals; Diclofenac; Hyperalgesia; Kynurenine; Neuralgia; Nociception; Rats; Rats, Sprague-Dawley; S

2023
Characterization of the Effects of L-4-Chlorokynurenine on Nociception in Rodents.
    The journal of pain, 2017, Volume: 18, Issue:10

    Topics: Amines; Analgesics; Animals; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dizocilpine

2017
Chronic trans-astaxanthin treatment exerts antihyperalgesic effect and corrects co-morbid depressive like behaviors in mice with chronic pain.
    Neuroscience letters, 2018, Jan-01, Volume: 662

    Topics: Analgesics; Animals; Behavior, Animal; Chronic Pain; Cytokines; Depression; Hydroxyindoleacetic Acid

2018
The L-kynurenine-probenecid combination reduces neuropathic pain in rats.
    European journal of pain (London, England), 2013, Volume: 17, Issue:9

    Topics: Animals; Drug Therapy, Combination; Female; Hyperalgesia; Kynurenine; Motor Activity; Neuralgia; Pai

2013
Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase.
    PLoS pathogens, 2016, Volume: 12, Issue:5

    Topics: Animals; Disease Models, Animal; Flow Cytometry; Hyperalgesia; Indoleamine-Pyrrole 2,3,-Dioxygenase;

2016
Acute single dose of ketamine relieves mechanical allodynia and consequent depression-like behaviors in a rat model.
    Neuroscience letters, 2016, Sep-19, Volume: 631

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Depression; Disease Models, Animal; Freund's Adjuv

2016