kynurenine has been researched along with Alcohol Abuse in 13 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "For this purpose, male and female abstinent AUD patients (N = 130) and healthy controls (N = 80) were clinically evaluated for substance use and mental disorders, and blood samples were collected to determine plasma concentrations of TRP, 5-HT, KYN and kynurenic acid (KA) using high performance liquid chromatography." | 3.96 | Plasma tryptophan and kynurenine pathway metabolites in abstinent patients with alcohol use disorder and high prevalence of psychiatric comorbidity. ( Araos, P; Colado, MI; Flores-López, M; García-Marchena, N; O'Shea, E; Pavón, FJ; Requena-Ocaña, N; Rodríguez de Fonseca, F; Rubio, G; Serrano, A; Suárez, J; Vidal, R, 2020) |
| "The role of the endogenous convulsant kynurenine (K) in the mechanisms of the development of epileptic seizures in alcoholic persons was studied on a clinical material of 63 patients suffering from alcoholism with the presence on the EEG of paroxysmal alterations without epileptic fits (n = 28) and alcoholic epilepsy (n = 35), epileptic patients not abusing alcohol (n = 20), and practically healthy subjects (n = 10)." | 3.68 | [Pathogenic role of the endogenous convulsant kynurenine in the mechanisms of development of epileptic attacks in alcoholics]. ( Eryshev, OF; Gromov, SA; Kartasheva, EV; Ryzhov, IV, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (53.85) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 5 (38.46) | 2.80 |
| Authors | Studies |
|---|---|
| Leclercq, S | 1 |
| Schwarz, M | 1 |
| Delzenne, NM | 1 |
| Stärkel, P | 1 |
| de Timary, P | 1 |
| Mechtcheriakov, S | 1 |
| Gleissenthall, GV | 1 |
| Geisler, S | 1 |
| Arnhard, K | 1 |
| Oberacher, H | 1 |
| Schurr, T | 1 |
| Kemmler, G | 1 |
| Unterberger, C | 1 |
| Fuchs, D | 1 |
| Wang, Z | 1 |
| Huang, S | 1 |
| Li, L | 1 |
| Wen, Y | 1 |
| Shang, D | 1 |
| Vidal, R | 1 |
| García-Marchena, N | 1 |
| O'Shea, E | 1 |
| Requena-Ocaña, N | 1 |
| Flores-López, M | 1 |
| Araos, P | 1 |
| Serrano, A | 1 |
| Suárez, J | 1 |
| Rubio, G | 1 |
| Rodríguez de Fonseca, F | 1 |
| Colado, MI | 1 |
| Pavón, FJ | 1 |
| Ho, MF | 1 |
| Zhang, C | 1 |
| Zhang, L | 1 |
| Wei, L | 1 |
| Zhou, Y | 1 |
| Moon, I | 1 |
| Geske, JR | 1 |
| Choi, DS | 1 |
| Biernacka, J | 1 |
| Frye, M | 1 |
| Wen, Z | 1 |
| Karpyak, VM | 1 |
| Li, H | 1 |
| Weinshilboum, R | 1 |
| PASQUARIELLO, G | 1 |
| QUADRI, A | 1 |
| TENCONI, LT | 1 |
| Krstulović, AM | 2 |
| Friedman, MJ | 2 |
| Colin, H | 1 |
| Guiochon, G | 1 |
| Gaspar, M | 1 |
| Pajer, KA | 1 |
| Branchey, L | 1 |
| Lieber, CS | 2 |
| Gromov, SA | 1 |
| Eryshev, OF | 1 |
| Kartasheva, EV | 1 |
| Ryzhov, IV | 1 |
| Buydens-Branchey, L | 1 |
| Branchey, M | 1 |
| Worner, TM | 1 |
| Zucker, D | 1 |
| Aramsombatdee, E | 1 |
| Severinghaus, JM | 1 |
| Brown, SJ | 1 |
| Payne, IR | 1 |
| Lu, GH | 1 |
| Meyer, K | 1 |
| Mainardi, L | 1 |
| Bissanti, A | 1 |
1 review available for kynurenine and Alcohol Abuse
| Article | Year |
|---|---|
Kynurenine metabolite changes in individuals with alcohol use disorder: A systematic review and meta-analysis.
Topics: Alcoholism; Humans; Kynurenic Acid; Kynurenine; Tryptophan | 2023 |
12 other studies available for kynurenine and Alcohol Abuse
| Article | Year |
|---|---|
Alterations of kynurenine pathway in alcohol use disorder and abstinence: a link with gut microbiota, peripheral inflammation and psychological symptoms.
Topics: Alcoholism; Gastrointestinal Microbiome; Humans; Inflammation; Kynurenic Acid; Kynurenine; Quinolini | 2021 |
Tryptophan-kynurenine metabolism during acute alcohol withdrawal in patients with alcohol use disorder: The role of immune activation.
Topics: Alcohol Drinking; Alcoholism; Biomarkers; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Ac | 2022 |
Plasma tryptophan and kynurenine pathway metabolites in abstinent patients with alcohol use disorder and high prevalence of psychiatric comorbidity.
Topics: Adolescent; Adult; Aged; Aging; Alcohol Abstinence; Alcoholism; Body Mass Index; Cross-Sectional Stu | 2020 |
TSPAN5 influences serotonin and kynurenine: pharmacogenomic mechanisms related to alcohol use disorder and acamprosate treatment response.
Topics: Acamprosate; Alcohol Drinking; Alcoholism; Depressive Disorder, Major; Humans; Induced Pluripotent S | 2021 |
TRYPTOPHAN-NICOTINIC ACID METABOLISM IN CHRONIC ALCOHOLICS.
Topics: Alcoholics; Alcoholism; Humans; Kynurenine; Liver Cirrhosis; Metabolism; Niacin; Nicotinic Acids; Tr | 1964 |
Analytical methodology for assays of serum tryptophan metabolites in control subjects and newly abstinent alcoholics: preliminary investigation by liquid chromatography with amperometric detection.
Topics: Adult; Aged; Alcoholism; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Humans | 1984 |
Activation of tryptophan pyrrolase after chronic alcohol administration.
Topics: Alcoholism; Animals; Enzyme Activation; Humans; Kynurenine; Liver; Rats; Rats, Inbred Strains; Trypt | 1982 |
[Pathogenic role of the endogenous convulsant kynurenine in the mechanisms of development of epileptic attacks in alcoholics].
Topics: Adult; Alcoholism; Cerebral Cortex; Electroencephalography; Epilepsy; Female; Humans; Kynurenine; Ma | 1991 |
Increase in tryptophan oxygenase activity in alcoholic patients.
Topics: Adult; Alcoholism; Humans; Hydrocortisone; Kinetics; Kynurenine; Liver Function Tests; Male; Middle | 1988 |
Altered conversion of tryptophan to kynurenine in newly abstinent alcoholics.
Topics: Adult; Alcoholism; Humans; Kynurenine; Liver; Male; Serotonin; Tryptophan; Tryptophan Oxygenase | 1988 |
Relationship of dietary tryptophan and niacin to tryptophan metabolism in alcoholics and nonalcoholics.
Topics: Acetates; Alcoholism; Aminohippuric Acids; Diet; Dietary Proteins; Female; Humans; Hydroxyindoleacet | 1974 |
[Various current findings in the problem of pellagra].
Topics: Alcoholism; Deficiency Diseases; Diet; Feeding Behavior; Hartnup Disease; Humans; Isoniazid; Isonico | 1968 |