kynurenine has been researched along with African Sleeping Sickness in 2 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasites Trypanosoma brucei rhodesiense or Trypanosoma brucei gambiense, and is a major cause of systemic and neurological disability throughout sub-Saharan Africa." | 1.35 | Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis. ( Barrett, MP; Bradley, B; Kennedy, PG; Rodgers, J; Stone, TW, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sternberg, JM | 1 |
| Forrest, CM | 1 |
| Dalton, RN | 1 |
| Turner, C | 1 |
| Rodgers, J | 2 |
| Stone, TW | 2 |
| Kennedy, PGE | 1 |
| Barrett, MP | 1 |
| Bradley, B | 1 |
| Kennedy, PG | 1 |
2 other studies available for kynurenine and African Sleeping Sickness
| Article | Year |
|---|---|
Kynurenine Pathway Activation in Human African Trypanosomiasis.
Topics: Adolescent; Adult; Aged; Biomarkers; Central Nervous System; Female; Humans; Inflammation; Interfero | 2017 |
Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis.
Topics: Animals; Blood-Brain Barrier; Central Nervous System Protozoal Infections; Female; Inhibitory Concen | 2009 |