kynurenine and Affective Disorders
kynurenine has been researched along with Affective Disorders in 9 studies
Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Weight loss diet lowered leptin levels in both groups by 46%, although not reaching significance." | 9.20 | Effects of a caloric restriction weight loss diet on tryptophan metabolism and inflammatory biomarkers in overweight adults. ( Berger, K; Fuchs, D; Strasser, B, 2015) |
" In this systematic review, we examine the relationship between kynurenine metabolites (kynurenine, kynurenic acid, tryptophan, quinolinic acid, the ratio of kynurenine and tryptophan) and mood disorders by conducting a meta-analysis." | 8.98 | Role of Kynurenine pathway and its metabolites in mood disorders: A systematic review and meta-analysis of clinical studies. ( Arnone, D; Dantzer, R; Salem, H; Saraykar, S; Selvaraj, S; Teixeira, AL, 2018) |
"The role of serotonin in the pathogenesis of depression is well-documented, while the involvement of other tryptophan (TRP) metabolites generated in the kynurenine pathway is less known." | 7.96 | Tryptophan Intake and Metabolism in Older Adults with Mood Disorders. ( Blasiak, J; Chojnacki, C; Chojnacki, J; Fila, M; Konrad, P; Popławski, T, 2020) |
"Mood disorders were evaluated by the Hamilton Anxiety Rating Scale (HAM-A) and the Hamilton Depression Rating Scale (HAM-D)." | 5.91 | Reduced Intake of Dietary Tryptophan Improves Beneficial Action of Budesonide in Patients with Lymphocytic Colitis and Mood Disorders. ( Blasiak, J; Błońska, A; Chojnacki, C; Chojnacki, J; Gąsiorowska, A; Konrad, P; Popławski, T; Zajdler, R, 2023) |
"Weight loss diet lowered leptin levels in both groups by 46%, although not reaching significance." | 5.20 | Effects of a caloric restriction weight loss diet on tryptophan metabolism and inflammatory biomarkers in overweight adults. ( Berger, K; Fuchs, D; Strasser, B, 2015) |
" In this systematic review, we examine the relationship between kynurenine metabolites (kynurenine, kynurenic acid, tryptophan, quinolinic acid, the ratio of kynurenine and tryptophan) and mood disorders by conducting a meta-analysis." | 4.98 | Role of Kynurenine pathway and its metabolites in mood disorders: A systematic review and meta-analysis of clinical studies. ( Arnone, D; Dantzer, R; Salem, H; Saraykar, S; Selvaraj, S; Teixeira, AL, 2018) |
"The role of serotonin in the pathogenesis of depression is well-documented, while the involvement of other tryptophan (TRP) metabolites generated in the kynurenine pathway is less known." | 3.96 | Tryptophan Intake and Metabolism in Older Adults with Mood Disorders. ( Blasiak, J; Chojnacki, C; Chojnacki, J; Fila, M; Konrad, P; Popławski, T, 2020) |
"Aprepitant treatment offers an opportunity to target inflammation and mood disorders frequently co-existing in chronic HIV infection." | 3.01 | Effect of aprepitant on kynurenine to tryptophan ratio in cART treated and cART naïve adults living with HIV. ( Douglas, SD; Evans, DL; Kinder, A; Pappa, V; Rappaport, J; Spitsin, S, 2021) |
"Mood disorders were evaluated by the Hamilton Anxiety Rating Scale (HAM-A) and the Hamilton Depression Rating Scale (HAM-D)." | 1.91 | Reduced Intake of Dietary Tryptophan Improves Beneficial Action of Budesonide in Patients with Lymphocytic Colitis and Mood Disorders. ( Blasiak, J; Błońska, A; Chojnacki, C; Chojnacki, J; Gąsiorowska, A; Konrad, P; Popławski, T; Zajdler, R, 2023) |
Research
Studies (9)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (11.11) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 4 (44.44) | 24.3611 |
2020's | 4 (44.44) | 2.80 |
Authors
Authors | Studies |
---|---|
Chojnacki, C | 2 |
Gąsiorowska, A | 1 |
Popławski, T | 2 |
Błońska, A | 1 |
Konrad, P | 2 |
Zajdler, R | 1 |
Chojnacki, J | 2 |
Blasiak, J | 2 |
Fila, M | 1 |
Spitsin, S | 1 |
Pappa, V | 1 |
Kinder, A | 1 |
Evans, DL | 1 |
Rappaport, J | 1 |
Douglas, SD | 1 |
Arnone, D | 1 |
Saraykar, S | 1 |
Salem, H | 1 |
Teixeira, AL | 1 |
Dantzer, R | 1 |
Selvaraj, S | 1 |
Maget, A | 1 |
Platzer, M | 1 |
Bengesser, SA | 1 |
Fellendorf, FT | 1 |
Birner, A | 1 |
Queissner, R | 1 |
Hamm, C | 1 |
Reininghaus, B | 1 |
Hecker, A | 1 |
Tomberger, L | 1 |
Pilz, R | 1 |
Dalkner, N | 1 |
Moll, N | 1 |
Schütze, G | 1 |
Schwarz, M | 1 |
Kapfhammer, HP | 1 |
Reininghaus, EZ | 1 |
Strasser, B | 1 |
Berger, K | 1 |
Fuchs, D | 2 |
Singh, R | 1 |
Savitz, J | 1 |
Teague, TK | 1 |
Polanski, DW | 1 |
Mayer, AR | 1 |
Bellgowan, PS | 1 |
Meier, TB | 1 |
Bechter, K | 1 |
Reiber, H | 1 |
Herzog, S | 1 |
Tumani, H | 1 |
Maxeiner, HG | 1 |
Lapin, IP | 1 |
Reviews
2 reviews available for kynurenine and Affective Disorders
Article | Year |
---|---|
Role of Kynurenine pathway and its metabolites in mood disorders: A systematic review and meta-analysis of clinical studies.
Topics: Humans; Kynurenic Acid; Kynurenine; Mood Disorders; Quinolinic Acid; Serotonin; Signal Transduction; | 2018 |
Kynurenines and anxiety.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Humans; Kynurenine; Maze Learning; Mice; Moo | 1996 |
Trials
2 trials available for kynurenine and Affective Disorders
Article | Year |
---|---|
Effect of aprepitant on kynurenine to tryptophan ratio in cART treated and cART naïve adults living with HIV.
Topics: Adult; Anti-HIV Agents; Aprepitant; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combina | 2021 |
Effects of a caloric restriction weight loss diet on tryptophan metabolism and inflammatory biomarkers in overweight adults.
Topics: Austria; Biomarkers; Body Mass Index; Caloric Restriction; Diet, Reducing; Female; Humans; Inflammat | 2015 |
Other Studies
5 other studies available for kynurenine and Affective Disorders
Article | Year |
---|---|
Reduced Intake of Dietary Tryptophan Improves Beneficial Action of Budesonide in Patients with Lymphocytic Colitis and Mood Disorders.
Topics: Budesonide; Colitis, Lymphocytic; Diet; Humans; Hydroxyindoleacetic Acid; Kynurenine; Mood Disorders | 2023 |
Tryptophan Intake and Metabolism in Older Adults with Mood Disorders.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Depression; Dietary Supplements; Eating; Female; Humans | 2020 |
Differences in Kynurenine Metabolism During Depressive, Manic, and Euthymic Phases of Bipolar Affective Disorder.
Topics: Adult; Bipolar Disorder; Depression; Female; Humans; Kynurenine; Male; Middle Aged; Mood Disorders | 2020 |
Mood symptoms correlate with kynurenine pathway metabolites following sports-related concussion.
Topics: Athletic Injuries; Brain Concussion; Follow-Up Studies; Football; Humans; Kynurenine; Male; Mood Dis | 2016 |
Cerebrospinal fluid analysis in affective and schizophrenic spectrum disorders: identification of subgroups with immune responses and blood-CSF barrier dysfunction.
Topics: Adult; Cohort Studies; Female; Humans; Immunoglobulins; International Classification of Diseases; Ky | 2010 |