Page last updated: 2024-10-18

kynurenine and 2019 Novel Coronavirus Disease

kynurenine has been researched along with 2019 Novel Coronavirus Disease in 43 studies

Kynurenine: A metabolite of the essential amino acid tryptophan metabolized via the tryptophan-kynurenine pathway.
kynurenine : A ketone that is alanine in which one of the methyl hydrogens is substituted by a 2-aminobenzoyl group.

Research Excerpts

ExcerptRelevanceReference
" The kynurenine and catecholamine metabolic pathways are modulated by inflammation and can affect systemic levels of serotonin and dopamine."8.31The effect of inflammation, SARS-CoV-2 infection, age and mental health on serotonin, and kynurenine and catecholamine pathway metabolites. ( Bruckner, T; Deisenhammer, EA; Egeter, J; Galffy, M; Giesinger, JM; Gostner, JM; Holzner, B; Hüfner, K; Lehmann, J; Nelles, P; Oberhammer, M; Rockenschaub, J; Sacher, M; Sperner-Unterweger, B; Tymoszuk, P; Vedova, S, 2023)
"This study examines whether activation of the tryptophan catabolite (TRYCAT) pathway is associated with anxiety symptoms due to Long COVID."8.31Anxiety due to Long COVID is partially driven by activation of the tryptophan catabolite (TRYCAT) pathway. ( Abed, AK; Al-Hakeim, HK; Almulla, AF; Maes, M; Rouf Moustafa, S, 2023)
" We review the literature concerning SARS-CoV2 infiltration and infection in the CNS and the prospects of synergy between stress, inflammation, and kynurenine pathway function during illness and recovery from Covid-19."5.12Covid-19 interface with drug misuse and substance use disorders. ( Cisneros, IE; Cunningham, KA, 2021)
" The kynurenine and catecholamine metabolic pathways are modulated by inflammation and can affect systemic levels of serotonin and dopamine."4.31The effect of inflammation, SARS-CoV-2 infection, age and mental health on serotonin, and kynurenine and catecholamine pathway metabolites. ( Bruckner, T; Deisenhammer, EA; Egeter, J; Galffy, M; Giesinger, JM; Gostner, JM; Holzner, B; Hüfner, K; Lehmann, J; Nelles, P; Oberhammer, M; Rockenschaub, J; Sacher, M; Sperner-Unterweger, B; Tymoszuk, P; Vedova, S, 2023)
"This study examines whether activation of the tryptophan catabolite (TRYCAT) pathway is associated with anxiety symptoms due to Long COVID."4.31Anxiety due to Long COVID is partially driven by activation of the tryptophan catabolite (TRYCAT) pathway. ( Abed, AK; Al-Hakeim, HK; Almulla, AF; Maes, M; Rouf Moustafa, S, 2023)
"Quinolinic acid (QA) is a metabolite of the kynurenine pathway, which is activated by inflammatory stimuli during viral infection."1.91The possible role of quinolinic acid as a predictive marker in patients with SARS-CoV-2. ( Baranyi, A; Enko, D; Herrmann, M; Meinitzer, A; Michaelis, S; Schnedl, WJ; Schneider, C; Zelzer, S, 2023)
" Bioavailability of tryptophan is an absolute requirement for proper cell functioning and synthesis of hormones, whereas its degradation products can cause cell death."1.72Indoleamine 2,3-dioxygenase (IDO)-1 and IDO-2 activity and severe course of COVID-19. ( Bugiani, M; Dijkhuis, A; Duitman, JW; Geeraerts, Z; Guo, L; Lutter, R; Nossent, EJ; Roos, E; Schurink, B; van der Valk, P; van Vught, L; Vaz, FM; Vlaar, AP; Yeh, SR, 2022)
"Viral sepsis has been proposed as an accurate term to describe all multisystemic dysregulations and clinical findings in severe and critically ill COVID-19 patients."1.62Immunometabolic signatures predict risk of progression to sepsis in COVID-19. ( Borrego, JC; Castañeda-Delgado, JE; Enciso-Moreno, JA; Fernández-Ruiz, JC; Herrera-Van Oostdam, AS; López, JA; López-Hernández, Y; Mandal, R; Monárrez-Espino, J; Ochoa-González, F; Oropeza-Valdez, JJ; Soto-Guzmán, E; Trejo Medinilla, FM; Wishart, DS; Zhang, L; Zheng, J, 2021)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's43 (100.00)2.80

Authors

AuthorsStudies
Herrera-Van Oostdam, AS1
Castañeda-Delgado, JE1
Oropeza-Valdez, JJ1
Borrego, JC1
Monárrez-Espino, J1
Zheng, J1
Mandal, R1
Zhang, L1
Soto-Guzmán, E1
Fernández-Ruiz, JC1
Ochoa-González, F1
Trejo Medinilla, FM1
López, JA1
Wishart, DS1
Enciso-Moreno, JA1
López-Hernández, Y1
D'Alessandro, A2
Thomas, T2
Akpan, IJ1
Reisz, JA2
Cendali, FI1
Gamboni, F1
Nemkov, T2
Thangaraju, K1
Katneni, U1
Tanaka, K1
Kahn, S1
Wei, AZ1
Valk, JE1
Hudson, KE2
Roh, D1
Moriconi, C1
Zimring, JC2
Hod, EA2
Spitalnik, SL2
Buehler, PW1
Francis, RO2
Vyavahare, S1
Kumar, S1
Cantu, N1
Kolhe, R1
Bollag, WB1
McGee-Lawrence, ME1
Hill, WD1
Hamrick, MW1
Isales, CM1
Fulzele, S1
Fang, J1
Feng, C1
Chen, W1
Hou, P1
Liu, Z1
Zuo, M1
Han, Y1
Xu, C1
Melino, G1
Verkhratsky, A1
Wang, Y1
Shao, C1
Shi, Y1
Jain, A2
D'Amora, P1
Silva, IDCG1
Budib, MA1
Ayache, R1
Silva, RMS1
Silva, FC1
Appel, RM1
Júnior, SS1
Pontes, HBD1
Alvarenga, AC1
Arima, EC1
Martins, WG1
Silva, NLF1
Diaz, RS1
Salzgeber, MB1
Palma, AM1
Evans, SS1
Nagourney, RA1
Guo, L2
Schurink, B1
Roos, E1
Nossent, EJ1
Duitman, JW2
Vlaar, AP1
van der Valk, P1
Vaz, FM2
Yeh, SR1
Geeraerts, Z1
Dijkhuis, A2
van Vught, L1
Bugiani, M2
Lutter, R2
Lamperti, M1
Doyle, DJ1
Ansone, L1
Briviba, M1
Silamikelis, I1
Terentjeva, A1
Perkons, I1
Birzniece, L1
Rovite, V1
Rozentale, B1
Viksna, L1
Kolesova, O1
Klavins, K1
Klovins, J1
Michaelis, S3
Zelzer, S3
Schnedl, WJ3
Baranyi, A3
Meinitzer, A3
Enko, D3
Cihan, M1
Doğan, Ö1
Ceran Serdar, C1
Altunçekiç Yıldırım, A1
Kurt, C1
Serdar, MA1
Guarnieri, T1
de Oliveira, JADP1
de Athaide, MM1
Rahman, AU1
de Mattos Barbosa, MG1
Jardim, MM1
Moraes, MO1
Pinheiro, RO1
Mingoti, MED1
Bertollo, AG1
Simões, JLB1
Francisco, GR1
Bagatini, MD1
Ignácio, ZM1
Patel, K1
Fernandez-Villamarin, M1
Ward, C1
Lord, JM1
Tino, P1
Mendes, PM1
Dewulf, JP1
Martin, M1
Marie, S1
Oguz, F1
Belkhir, L1
De Greef, J1
Yombi, JC1
Wittebole, X1
Laterre, PF1
Jadoul, M1
Gatto, L1
Bommer, GT1
Morelle, J1
Kucukkarapinar, M1
Yay-Pence, A1
Yildiz, Y1
Buyukkoruk, M1
Yaz-Aydin, G1
Deveci-Bulut, TS1
Gulbahar, O1
Senol, E1
Candansayar, S1
Almulla, AF2
Supasitthumrong, T1
Tunvirachaisakul, C1
Algon, AAA1
Al-Hakeim, HK2
Maes, M2
Ceballos, FC1
Virseda-Berdices, A1
Resino, S1
Ryan, P1
Martínez-González, O1
Peréz-García, F1
Martin-Vicente, M1
Brochado-Kith, O1
Blancas, R1
Bartolome-Sánchez, S1
Vidal-Alcántara, EJ1
Albóniga-Díez, OE1
Cuadros-González, J1
Blanca-López, N1
Martínez, I1
Martinez-Acitores, IR1
Barbas, C1
Fernández-Rodríguez, A1
Jiménez-Sousa, MÁ1
Saito, K1
Ishikawa, R1
Kitamura, I1
Ogawa, K1
Arakawa, N1
Sun, Y1
Imai, K1
Maeda, T1
Saito, Y1
Hasegawa, C1
Bizjak, DA1
Stangl, M1
Börner, N1
Bösch, F1
Durner, J1
Drunin, G1
Buhl, JL1
Abendroth, D1
Saheb Sharif-Askari, N1
Soares, NC1
Mohamed, HA1
Saheb Sharif-Askari, F1
Alsayed, HAH1
Al-Hroub, H1
Salameh, L1
Osman, RS1
Mahboub, B1
Hamid, Q1
Semreen, MH1
Halwani, R1
Schneider, C2
Herrmann, M2
Schuller, M3
Oberhuber, M3
Prietl, B3
Zügner, E3
Prugger, EM3
Magnes, C3
Kirsch, AH3
Schmaldienst, S3
Pieber, T3
Brodmann, M3
Rosenkranz, AR3
Eller, P3
Eller, K3
Ruffieux, H1
Hanson, AL1
Lodge, S1
Lawler, NG2
Whiley, L2
Gray, N2
Nolan, TH1
Bergamaschi, L1
Mescia, F1
Turner, L1
de Sa, A1
Pelly, VS1
Kotagiri, P1
Kingston, N1
Bradley, JR1
Holmes, E2
Wist, J1
Nicholson, JK2
Lyons, PA1
Smith, KGC1
Richardson, S1
Bantug, GR1
Hess, C1
Krčmová, LK1
Matoušová, K1
Javorská, L1
Šmahel, P1
Skála, M1
Koblížek, V1
Škop, J1
Turoňová, D1
Gančarčíková, M1
Melichar, B1
Cysique, LA1
Jakabek, D1
Bracken, SG1
Allen-Davidian, Y1
Heng, B1
Chow, S1
Dehhaghi, M1
Staats Pires, A1
Darley, DR1
Byrne, A1
Phetsouphanh, C1
Kelleher, A1
Dore, GJ1
Matthews, GV1
Guillemin, GJ1
Brew, BJ1
Hüfner, K1
Vedova, S1
Tymoszuk, P1
Nelles, P1
Bruckner, T1
Deisenhammer, EA1
Egeter, J1
Galffy, M1
Giesinger, JM1
Lehmann, J1
Oberhammer, M1
Rockenschaub, J1
Sacher, M1
Holzner, B1
Gostner, JM2
Sperner-Unterweger, B1
Badawy, AA2
Appelman, B1
Mooij-Kalverda, K1
Houtkooper, RH1
van Weeghel, M1
Dekker, T1
Smids, BS1
Brinkman, P1
Sikkens, JJ1
Lavell, HAA1
Wüst, RCI1
van Vugt, M1
Abed, AK1
Rouf Moustafa, S1
Rus, CP1
de Vries, BEK1
de Vries, IEJ1
Nutma, I1
Kooij, JJS1
Stefanoni, D1
Bertolone, L1
Hansen, KC1
Turski, WA1
Wnorowski, A1
Turski, GN1
Turski, CA1
Turski, L1
Robertson, J1
Nilsson, S1
Andersson, LM1
Fuchs, D1
Gisslen, M1
Lionetto, L1
Ulivieri, M1
Capi, M1
De Bernardini, D1
Fazio, F1
Petrucca, A1
Pomes, LM1
De Luca, O1
Gentile, G1
Casolla, B1
Curto, M1
Salerno, G1
Schillizzi, S1
Torre, MS1
Santino, I1
Rocco, M1
Marchetti, P1
Aceti, A1
Ricci, A1
Bonfini, R1
Nicoletti, F1
Simmaco, M1
Borro, M1
Collier, ME1
Zhang, S1
Scrutton, NS1
Giorgini, F1
Kimhofer, T1
Boughton, B1
Gay, M1
Yang, R1
Morillon, AC1
Chin, ST1
Ryan, M1
Begum, S1
Bong, SH1
Coudert, JD1
Edgar, D1
Raby, E1
Pettersson, S1
Richards, T1
Marín-Corral, J1
Rodríguez-Morató, J1
Gomez-Gomez, A1
Pascual-Guardia, S1
Muñoz-Bermúdez, R1
Salazar-Degracia, A1
Pérez-Terán, P1
Restrepo, MI1
Khymenets, O1
Haro, N1
Masclans, JR1
Pozo, OJ1
Qin, WH1
Liu, CL1
Jiang, YH1
Hu, B1
Wang, HY1
Fu, J1
Cisneros, IE1
Cunningham, KA1

Reviews

10 reviews available for kynurenine and 2019 Novel Coronavirus Disease

ArticleYear
Tryptophan-Kynurenine Pathway in COVID-19-Dependent Musculoskeletal Pathology: A Minireview.
    Mediators of inflammation, 2021, Volume: 2021

    Topics: Animals; Bone Diseases; COVID-19; Humans; Kynurenine; Muscular Diseases; Receptors, Aryl Hydrocarbon

2021
Redressing the interactions between stem cells and immune system in tissue regeneration.
    Biology direct, 2021, 10-20, Volume: 16, Issue:1

    Topics: Animals; Cell Adhesion Molecules; Cell Differentiation; Cell Proliferation; COVID-19; Humans; Immune

2021
Hypothesis: Emerging Roles for Aryl Hydrocarbon Receptor in Orchestrating CoV-2-Related Inflammation.
    Cells, 2022, 02-13, Volume: 11, Issue:4

    Topics: Adaptive Immunity; Amino Acid Transport Systems, Neutral; Angiotensin-Converting Enzyme 2; Basic Hel

2022
Kynurenines in the Pathogenesis of Peripheral Neuropathy During Leprosy and COVID-19.
    Frontiers in cellular and infection microbiology, 2022, Volume: 12

    Topics: COVID-19; Humans; Kynurenine; Leprosy; Peripheral Nervous System Diseases; SARS-CoV-2; Tryptophan

2022
COVID-19, Oxidative Stress, and Neuroinflammation in the Depression Route.
    Journal of molecular neuroscience : MN, 2022, Volume: 72, Issue:6

    Topics: COVID-19; Depression; Depressive Disorder, Major; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Infl

2022
The tryptophan catabolite or kynurenine pathway in COVID-19 and critical COVID-19: a systematic review and meta-analysis.
    BMC infectious diseases, 2022, Jul-15, Volume: 22, Issue:1

    Topics: COVID-19; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Tryptophan

2022
AhR and IDO1 in pathogenesis of Covid-19 and the "Systemic AhR Activation Syndrome:" a translational review and therapeutic perspectives.
    Restorative neurology and neuroscience, 2020, Volume: 38, Issue:4

    Topics: Air Pollutants; Betacoronavirus; Calcitriol; Coronavirus Infections; COVID-19; COVID-19 Drug Treatme

2020
Immunotherapy of COVID-19 with poly (ADP-ribose) polymerase inhibitors: starting with nicotinamide.
    Bioscience reports, 2020, 10-30, Volume: 40, Issue:10

    Topics: Basic Helix-Loop-Helix Transcription Factors; Betacoronavirus; Cell Line; Coronavirus Infections; CO

2020
Inflammation control and improvement of cognitive function in COVID-19 infections: is there a role for kynurenine 3-monooxygenase inhibition?
    Drug discovery today, 2021, Volume: 26, Issue:6

    Topics: Animals; Cognition; COVID-19; Humans; Inflammation; Kynurenine; Kynurenine 3-Monooxygenase; Neuropro

2021
Covid-19 interface with drug misuse and substance use disorders.
    Neuropharmacology, 2021, 10-15, Volume: 198

    Topics: Adaptation, Psychological; Angiotensin-Converting Enzyme 2; Animals; Axons; Comorbidity; COVID-19; D

2021

Other Studies

33 other studies available for kynurenine and 2019 Novel Coronavirus Disease

ArticleYear
Immunometabolic signatures predict risk of progression to sepsis in COVID-19.
    PloS one, 2021, Volume: 16, Issue:8

    Topics: Adult; Area Under Curve; Chemokines; COVID-19; Cytokines; Female; Humans; Kynurenine; Lymphocytes; M

2021
Biological and Clinical Factors Contributing to the Metabolic Heterogeneity of Hospitalized Patients with and without COVID-19.
    Cells, 2021, 09-02, Volume: 10, Issue:9

    Topics: Acute Disease; Adult; Amino Acids; Body Mass Index; Carnitine; Cohort Studies; COVID-19; Fatty Acids

2021
Deregulated kynurenine metabolism - An alternate hypothesis for COVID-19 associated anosmia.
    Medical hypotheses, 2021, Volume: 157

    Topics: Anosmia; COVID-19; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; SARS-CoV-2; Tryptophan

2021
Towards risk stratification and prediction of disease severity and mortality in COVID-19: Next generation metabolomics for the measurement of host response to COVID-19 infection.
    PloS one, 2021, Volume: 16, Issue:12

    Topics: Adult; Aged; Area Under Curve; Carnitine; Citrulline; COVID-19; Female; Glutamic Acid; Humans; Kynur

2021
Indoleamine 2,3-dioxygenase (IDO)-1 and IDO-2 activity and severe course of COVID-19.
    The Journal of pathology, 2022, Volume: 256, Issue:3

    Topics: 3-Hydroxyanthranilic Acid; Adult; Aged; Apoptosis; Autopsy; Brain; COVID-19; Humans; Indoleamine-Pyr

2022
COVID-19, perioperative neurocognitive disorder and SARS-CoV-2-induced dysregulation of the renin-angiotensin system and kynurenine metabolism. Comment on Br J Anaesth 2021; 127: e113-e115.
    British journal of anaesthesia, 2022, Volume: 128, Issue:2

    Topics: COVID-19; Humans; Kynurenine; Neurocognitive Disorders; Renin-Angiotensin System; SARS-CoV-2

2022
Amino Acid Metabolism is Significantly Altered at the Time of Admission in Hospital for Severe COVID-19 Patients: Findings from Longitudinal Targeted Metabolomics Analysis.
    Microbiology spectrum, 2021, 12-22, Volume: 9, Issue:3

    Topics: Amino Acids; Biomarkers; COVID-19; Hospitals; Host Microbial Interactions; Humans; Kynurenine; Metab

2021
Assessment of tryptophan and kynurenine as prognostic markers in patients with SARS-CoV-2.
    Clinica chimica acta; international journal of clinical chemistry, 2022, Jan-15, Volume: 525

    Topics: COVID-19; Humans; Kynurenine; Prognosis; SARS-CoV-2; Tryptophan

2022
Kynurenine pathway in Coronavirus disease (COVID-19): Potential role in prognosis.
    Journal of clinical laboratory analysis, 2022, Volume: 36, Issue:3

    Topics: Adult; Aged; COVID-19; Female; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; Picolinic Acid

2022
Establishing a quantitative fluorescence assay for the rapid detection of kynurenine in urine.
    The Analyst, 2022, May-03, Volume: 147, Issue:9

    Topics: Chromatography, High Pressure Liquid; COVID-19; Humans; Kynurenine

2022
Urine metabolomics links dysregulation of the tryptophan-kynurenine pathway to inflammation and severity of COVID-19.
    Scientific reports, 2022, 06-15, Volume: 12, Issue:1

    Topics: Biomarkers; Chromatography, Liquid; COVID-19; Humans; Inflammation; Kynurenine; Metabolomics; SARS-C

2022
Psychological outcomes of COVID-19 survivors at sixth months after diagnose: the role of kynurenine pathway metabolites in depression, anxiety, and stress.
    Journal of neural transmission (Vienna, Austria : 1996), 2022, Volume: 129, Issue:8

    Topics: Anxiety; Biomarkers; COVID-19; Depression; Humans; Kynurenic Acid; Kynurenine; Survivors; Tryptophan

2022
Metabolic Profiling at COVID-19 Onset Shows Disease Severity and Sex-Specific Dysregulation.
    Frontiers in immunology, 2022, Volume: 13

    Topics: COVID-19; Cross-Sectional Studies; Cytokines; Disease Progression; Female; Humans; Kynurenine; Male;

2022
Characterization of serotonin as a candidate biomarker of severity and prognosis of COVID-19 using LC/MS analysis.
    Journal of pharmacological sciences, 2022, Volume: 150, Issue:2

    Topics: Biomarkers; Chromatography, Liquid; COVID-19; Humans; Kynurenine; Mass Spectrometry; Prognosis; Sero

2022
Kynurenine serves as useful biomarker in acute, Long- and Post-COVID-19 diagnostics.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; C-Reactive Protein; COVID-19; COVID-19 Testi

2022
Saliva metabolomic profile of COVID-19 patients associates with disease severity.
    Metabolomics : Official journal of the Metabolomic Society, 2022, 10-22, Volume: 18, Issue:11

    Topics: Aminolevulinic Acid; Biomarkers; C-Reactive Protein; Chromatography, Liquid; COVID-19; Humans; Kynur

2022
Alteration of the kynurenine pathway is inversely associated with the humoral immune response in patients with SARS-CoV-2.
    Clinica chimica acta; international journal of clinical chemistry, 2022, Dec-01, Volume: 537

    Topics: COVID-19; Humans; Immunity, Humoral; Kynurenine; SARS-CoV-2; Tryptophan

2022
Alterations in the Kynurenine-Tryptophan Pathway and Lipid Dysregulation Are Preserved Features of COVID-19 in Hemodialysis.
    International journal of molecular sciences, 2022, Nov-15, Volume: 23, Issue:22

    Topics: COVID-19; Humans; Kynurenine; Lipids; Renal Dialysis; Tryptophan

2022
Alterations in the Kynurenine-Tryptophan Pathway and Lipid Dysregulation Are Preserved Features of COVID-19 in Hemodialysis.
    International journal of molecular sciences, 2022, Nov-15, Volume: 23, Issue:22

    Topics: COVID-19; Humans; Kynurenine; Lipids; Renal Dialysis; Tryptophan

2022
Alterations in the Kynurenine-Tryptophan Pathway and Lipid Dysregulation Are Preserved Features of COVID-19 in Hemodialysis.
    International journal of molecular sciences, 2022, Nov-15, Volume: 23, Issue:22

    Topics: COVID-19; Humans; Kynurenine; Lipids; Renal Dialysis; Tryptophan

2022
Alterations in the Kynurenine-Tryptophan Pathway and Lipid Dysregulation Are Preserved Features of COVID-19 in Hemodialysis.
    International journal of molecular sciences, 2022, Nov-15, Volume: 23, Issue:22

    Topics: COVID-19; Humans; Kynurenine; Lipids; Renal Dialysis; Tryptophan

2022
Alterations in the Kynurenine-Tryptophan Pathway and Lipid Dysregulation Are Preserved Features of COVID-19 in Hemodialysis.
    International journal of molecular sciences, 2022, Nov-15, Volume: 23, Issue:22

    Topics: COVID-19; Humans; Kynurenine; Lipids; Renal Dialysis; Tryptophan

2022
Alterations in the Kynurenine-Tryptophan Pathway and Lipid Dysregulation Are Preserved Features of COVID-19 in Hemodialysis.
    International journal of molecular sciences, 2022, Nov-15, Volume: 23, Issue:22

    Topics: COVID-19; Humans; Kynurenine; Lipids; Renal Dialysis; Tryptophan

2022
Alterations in the Kynurenine-Tryptophan Pathway and Lipid Dysregulation Are Preserved Features of COVID-19 in Hemodialysis.
    International journal of molecular sciences, 2022, Nov-15, Volume: 23, Issue:22

    Topics: COVID-19; Humans; Kynurenine; Lipids; Renal Dialysis; Tryptophan

2022
Alterations in the Kynurenine-Tryptophan Pathway and Lipid Dysregulation Are Preserved Features of COVID-19 in Hemodialysis.
    International journal of molecular sciences, 2022, Nov-15, Volume: 23, Issue:22

    Topics: COVID-19; Humans; Kynurenine; Lipids; Renal Dialysis; Tryptophan

2022
Alterations in the Kynurenine-Tryptophan Pathway and Lipid Dysregulation Are Preserved Features of COVID-19 in Hemodialysis.
    International journal of molecular sciences, 2022, Nov-15, Volume: 23, Issue:22

    Topics: COVID-19; Humans; Kynurenine; Lipids; Renal Dialysis; Tryptophan

2022
A patient-centric modeling framework captures recovery from SARS-CoV-2 infection.
    Nature immunology, 2023, Volume: 24, Issue:2

    Topics: COVID-19; Humans; Kynurenine; Patient-Centered Care; Post-Acute COVID-19 Syndrome; SARS-CoV-2

2023
Neopterin and kynurenine in serum and urine as prognostic biomarkers in hospitalized patients with delta and omicron variant SARS-CoV-2 infection.
    Clinical chemistry and laboratory medicine, 2023, 10-26, Volume: 61, Issue:11

    Topics: Biomarkers; COVID-19; Humans; Kynurenine; Neopterin; Oxygen; Prognosis; SARS-CoV-2; Tryptophan

2023
The kynurenine pathway relates to post-acute COVID-19 objective cognitive impairment and PASC.
    Annals of clinical and translational neurology, 2023, Volume: 10, Issue:8

    Topics: Adult; Biomarkers; Cognitive Dysfunction; COVID-19; Female; Humans; Kynurenine; Male; Middle Aged; P

2023
The effect of inflammation, SARS-CoV-2 infection, age and mental health on serotonin, and kynurenine and catecholamine pathway metabolites.
    Psychoneuroendocrinology, 2023, Volume: 156

    Topics: COVID-19; Cross-Sectional Studies; Dopamine; Humans; Inflammation; Kynurenine; Mental Health; Phenyl

2023
The kynurenine pathway of tryptophan metabolism: a neglected therapeutic target of COVID-19 pathophysiology and immunotherapy.
    Bioscience reports, 2023, 08-31, Volume: 43, Issue:8

    Topics: COVID-19; Humans; Immunotherapy; Kynurenine; NAD; Poly(ADP-ribose) Polymerase Inhibitors; SARS-CoV-2

2023
Prolonged indoleamine 2,3-dioxygenase-2 activity and associated cellular stress in post-acute sequelae of SARS-CoV-2 infection.
    EBioMedicine, 2023, Volume: 94

    Topics: Chromatography, Liquid; COVID-19; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Leukocyt

2023
Anxiety due to Long COVID is partially driven by activation of the tryptophan catabolite (TRYCAT) pathway.
    Asian journal of psychiatry, 2023, Volume: 88

    Topics: Anxiety; COVID-19; Humans; Kynurenine; Post-Acute COVID-19 Syndrome; Tryptophan

2023
The possible role of quinolinic acid as a predictive marker in patients with SARS-CoV-2.
    Clinica chimica acta; international journal of clinical chemistry, 2023, Oct-01, Volume: 550

    Topics: C-Reactive Protein; COVID-19; Humans; Kynurenine; Procalcitonin; Quinolinic Acid; SARS-CoV-2; Trypto

2023
Treatment of 95 post-Covid patients with SSRIs.
    Scientific reports, 2023, 11-02, Volume: 13, Issue:1

    Topics: COVID-19; Fatigue Syndrome, Chronic; Humans; Kynurenine; Primary Dysautonomias; Selective Serotonin

2023
COVID-19 infection alters kynurenine and fatty acid metabolism, correlating with IL-6 levels and renal status.
    JCI insight, 2020, 07-23, Volume: 5, Issue:14

    Topics: Adult; Aged; Amino Acids; Betacoronavirus; Blood Glucose; Case-Control Studies; Coronavirus Infectio

2020
Serum neopterin levels in relation to mild and severe COVID-19.
    BMC infectious diseases, 2020, Dec-10, Volume: 20, Issue:1

    Topics: Adult; Aged; Biomarkers; COVID-19; Critical Care; Female; Hospitalization; Humans; Kynurenine; Male;

2020
Increased kynurenine-to-tryptophan ratio in the serum of patients infected with SARS-CoV2: An observational cohort study.
    Biochimica et biophysica acta. Molecular basis of disease, 2021, 03-01, Volume: 1867, Issue:3

    Topics: Aged; Biomarkers; COVID-19; Female; Humans; Kynurenine; Lymphocyte Count; Male; Middle Aged; SARS-Co

2021
Systemic Perturbations in Amine and Kynurenine Metabolism Associated with Acute SARS-CoV-2 Infection and Inflammatory Cytokine Responses.
    Journal of proteome research, 2021, 05-07, Volume: 20, Issue:5

    Topics: Amines; COVID-19; Cytokines; Humans; Kynurenine; SARS-CoV-2

2021
Metabolic Signatures Associated with Severity in Hospitalized COVID-19 Patients.
    International journal of molecular sciences, 2021, Apr-30, Volume: 22, Issue:9

    Topics: Adult; Aged; Biomarkers; Ceramides; COVID-19; Female; Hospitalization; Humans; Kynurenine; Male; Met

2021
Gut ACE2 Expression, Tryptophan Deficiency, and Inflammatory Responses The Potential Connection That Should Not Be Ignored During SARS-CoV-2 Infection.
    Cellular and molecular gastroenterology and hepatology, 2021, Volume: 12, Issue:4

    Topics: Angiotensin-Converting Enzyme 2; Animals; COVID-19; Cytokines; Epithelial Cells; Inflammation; Intes

2021