kynurenic acid has been researched along with Scleroderma, Systemic in 6 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Endothelial dysfunction occurs early in systemic sclerosis (SSc), leading to tissue hypoxia, vasoconstriction and fibrosis." | 1.91 | Serum kynurenic acid is lower in systemic sclerosis patients with microvascular damage of hands. ( Colalillo, A; Pellicano, C; Rosato, E, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Pellicano, C | 1 |
| Colalillo, A | 1 |
| Rosato, E | 1 |
| PINALS, RS | 1 |
| Leklem, JE | 1 |
| Brown, RR | 2 |
| Hankes, LV | 2 |
| Jansen, CR | 1 |
| Houpt, JB | 1 |
| Ogryzlo, MA | 1 |
| Hunt, M | 1 |
| Leklem, J | 1 |
| Schmaeler, M | 1 |
| Jesseph, J | 1 |
| Sönnichsen, N | 1 |
| Feuerstein, M | 1 |
| Kölzsch, J | 1 |
6 other studies available for kynurenic acid and Scleroderma, Systemic
| Article | Year |
|---|---|
Serum kynurenic acid is lower in systemic sclerosis patients with microvascular damage of hands.
Topics: Endothelial Cells; Hand; Humans; Kynurenic Acid; Microscopic Angioscopy; Nails; Scleroderma, Systemi | 2023 |
TRYPTOPHAN METABOLISM IN RHEUMATIC DISEASE.
Topics: Amino Acids; Arthritis; Arthritis, Rheumatoid; Chromatography; Humans; Kynurenic Acid; Kynurenine; L | 1964 |
A mechanism for the formation in vivo of the 8-methyl ether of xanthurenic acid in humans.
Topics: Adult; Female; Humans; Kynurenic Acid; Kynurenine; Male; Methionine; Methyl Ethers; Middle Aged; Pel | 1975 |
Tryptophan metabolism in man (with special reference to rheumatoid arthritis and scleroderma).
Topics: Arthritis, Rheumatoid; Aspirin; Cystinuria; Drug Synergism; Edetic Acid; Humans; Kynurenic Acid; Kyn | 1973 |
Metabolism of C 14 labeled enantiomers of tryptophan, kynurenine and hydroxykynurenine in humans with scleroderma.
Topics: Adult; Carbon Dioxide; Carbon Isotopes; Female; Humans; Kynurenic Acid; Kynurenine; Middle Aged; Phe | 1972 |
[Studies on the excretion of tryptophan metabolites in patients with circumscript and progressive scleroderma].
Topics: Adult; Aged; Female; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; ortho-Aminobenzoates; Sc | 1968 |