kynurenic acid has been researched along with Renal Insufficiency, Chronic in 6 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adults with chronic kidney disease (CKD) exhibit alterations in tryptophan metabolism, mainly via the kynurenine pathway, due to higher enzymatic activity induced mainly by inflammation." | 7.83 | Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study. ( Davies, N; Hilder, EF; Jose, MD; Karu, N; McKercher, C; Nichols, DS; Shellie, RA, 2016) |
| "Adults with chronic kidney disease (CKD) exhibit alterations in tryptophan metabolism, mainly via the kynurenine pathway, due to higher enzymatic activity induced mainly by inflammation." | 3.83 | Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study. ( Davies, N; Hilder, EF; Jose, MD; Karu, N; McKercher, C; Nichols, DS; Shellie, RA, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y | 1 |
| Zelnick, LR | 1 |
| Huber, MP | 1 |
| Wang, K | 1 |
| Bansal, N | 1 |
| Hoofnagle, AN | 1 |
| Paranji, RK | 1 |
| Heckbert, SR | 1 |
| Weiss, NS | 1 |
| Go, AS | 1 |
| Hsu, CY | 1 |
| Feldman, HI | 1 |
| Waikar, SS | 1 |
| Mehta, RC | 1 |
| Srivastava, A | 1 |
| Seliger, SL | 1 |
| Lash, JP | 1 |
| Porter, AC | 1 |
| Raj, DS | 1 |
| Kestenbaum, BR | 1 |
| Mo, Y | 1 |
| Jie, X | 1 |
| Wang, L | 1 |
| Ji, C | 1 |
| Gu, Y | 1 |
| Lu, Z | 1 |
| Liu, X | 1 |
| Grams, ME | 1 |
| Tin, A | 1 |
| Rebholz, CM | 1 |
| Shafi, T | 1 |
| Köttgen, A | 1 |
| Perrone, RD | 1 |
| Sarnak, MJ | 1 |
| Inker, LA | 1 |
| Levey, AS | 1 |
| Coresh, J | 1 |
| Zhao, J | 1 |
| Karu, N | 1 |
| McKercher, C | 1 |
| Nichols, DS | 1 |
| Davies, N | 1 |
| Shellie, RA | 1 |
| Hilder, EF | 1 |
| Jose, MD | 1 |
| Schefold, JC | 1 |
| Zeden, JP | 1 |
| Fotopoulou, C | 1 |
| von Haehling, S | 1 |
| Pschowski, R | 1 |
| Hasper, D | 1 |
| Volk, HD | 1 |
| Schuett, C | 1 |
| Reinke, P | 1 |
1 trial available for kynurenic acid and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Plasma kynurenic acid/tryptophan ratio: a sensitive and reliable biomarker for the assessment of renal function.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Female; Humans; Hypertension; Kidney Function Tes | 2013 |
5 other studies available for kynurenic acid and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Association Between Kidney Clearance of Secretory Solutes and Cardiovascular Events: The Chronic Renal Insufficiency Cohort (CRIC) Study.
Topics: Aged; Albuminuria; Chromatography, Liquid; Cohort Studies; Cresols; Female; Glomerular Filtration Ra | 2021 |
Bupi Yishen formula attenuates kidney injury in 5/6 nephrectomized rats via the tryptophan-kynurenic acid-aryl hydrocarbon receptor pathway.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Drugs, Chinese Herbal; Inflammation; Kidney; | 2021 |
Metabolomic Alterations Associated with Cause of CKD.
Topics: Adult; Citrulline; Deoxyglucose; Female; Glomerulonephritis; Guanosine; Hippurates; Homovanillic Aci | 2017 |
Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study.
Topics: Aged; Aged, 80 and over; Anxiety; Biomarkers; Cognition; Cross-Sectional Studies; Depression; Female | 2016 |
Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms.
Topics: 5-Hydroxytryptophan; Adult; Aged; C-Reactive Protein; Case-Control Studies; Creatinine; Female; Huma | 2009 |