kynurenic acid has been researched along with Osteoarthritis in 4 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previously, we have demonstrated that kynurenic acid (KYNA), an endogenous metabolite of tryptophan formed along kynurenine pathway, is present in synovial fluid of rheumatoid arthritis (RA) and osteoarthritis (OA) patients." | 7.88 | Quinaldic acid in synovial fluid of patients with rheumatoid arthritis and osteoarthritis and its effect on synoviocytes in vitro. ( Langner, E; Nowicka-Stążka, P; Parada-Turska, J; Rzeski, W; Turski, W, 2018) |
| "Previously we demonstrated that kynurenic acid (KYNA), an endogenous metabolite of kynurenine, is present in the synovial fluid of patients with rheumatoid arthritis (RA)." | 7.79 | Kynurenic acid in synovial fluid and serum of patients with rheumatoid arthritis, spondyloarthropathy, and osteoarthritis. ( Majdan, M; Parada-Turska, J; Zgrajka, W, 2013) |
| "Previously, we have demonstrated that kynurenic acid (KYNA), an endogenous metabolite of tryptophan formed along kynurenine pathway, is present in synovial fluid of rheumatoid arthritis (RA) and osteoarthritis (OA) patients." | 3.88 | Quinaldic acid in synovial fluid of patients with rheumatoid arthritis and osteoarthritis and its effect on synoviocytes in vitro. ( Langner, E; Nowicka-Stążka, P; Parada-Turska, J; Rzeski, W; Turski, W, 2018) |
| "Previously we demonstrated that kynurenic acid (KYNA), an endogenous metabolite of kynurenine, is present in the synovial fluid of patients with rheumatoid arthritis (RA)." | 3.79 | Kynurenic acid in synovial fluid and serum of patients with rheumatoid arthritis, spondyloarthropathy, and osteoarthritis. ( Majdan, M; Parada-Turska, J; Zgrajka, W, 2013) |
| "Kynurenic acid (KYNA) is a neuroactive metabolite that interacts with NMDA, AMPA/kainate and alpha 7 nicotinic receptors." | 1.42 | The inimitable kynurenic acid: the roles of different ionotropic receptors in the action of kynurenic acid at a spinal level. ( Bohar, Z; Horvath, G; Kekesi, G; Pardutz, A; Petrovszki, Z; Safrany-Fark, A; Tar, L; Tuboly, G; Vecsei, L, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nowicka-Stążka, P | 1 |
| Langner, E | 1 |
| Turski, W | 1 |
| Rzeski, W | 1 |
| Parada-Turska, J | 2 |
| Zgrajka, W | 1 |
| Majdan, M | 1 |
| Tuboly, G | 1 |
| Tar, L | 1 |
| Bohar, Z | 1 |
| Safrany-Fark, A | 1 |
| Petrovszki, Z | 1 |
| Kekesi, G | 1 |
| Vecsei, L | 1 |
| Pardutz, A | 1 |
| Horvath, G | 1 |
| Igari, T | 1 |
| Tsuchizawa, M | 1 |
4 other studies available for kynurenic acid and Osteoarthritis
| Article | Year |
|---|---|
Quinaldic acid in synovial fluid of patients with rheumatoid arthritis and osteoarthritis and its effect on synoviocytes in vitro.
Topics: Adult; Aged; Aged, 80 and over; Animals; Arthritis, Rheumatoid; Cell Proliferation; Cells, Cultured; | 2018 |
Kynurenic acid in synovial fluid and serum of patients with rheumatoid arthritis, spondyloarthropathy, and osteoarthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Kynurenic Acid; Male; Middle Aged; Osteoarthriti | 2013 |
The inimitable kynurenic acid: the roles of different ionotropic receptors in the action of kynurenic acid at a spinal level.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Analgesics; Animals; Disease Models, Animal; Dose-Response | 2015 |
Tryptophan metabolism in the synovial fluid in rheumatoid arthritis and osteoarthritis.
Topics: Arthritis, Rheumatoid; Blood Sedimentation; Humans; Kynurenic Acid; Kynurenine; Nicotinic Acids; ort | 1969 |