Page last updated: 2024-10-30

kynurenic acid and Obesity

kynurenic acid has been researched along with Obesity in 10 studies

Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"Obesity is associated with impaired learning, but the mechanisms underlying this cognitive dysfunction are poorly understood."5.91Obesity-Induced Memory Deficits in Female Rats Are Oestrous Cycle Dependent and Linked to Impaired Brain Kynurenine Pathway Metabolism. ( Bolaños-Jiménez, F; Croyal, M; García Santillán, JA; Gourdel, M; Mezo-González, CE; Reyes-Castro, LA, 2023)
" One of the factors recently recognized to influence metabolism and weight gain is kynurenic acid (KYNA), an agonist of G protein-coupled receptor (GPR35)."3.91Kynurenic acid as the neglected ingredient of commercial baby formulas. ( Bednarski, J; Debinska, I; Dobrowolski, P; Gawel, K; Kocki, T; Milart, P; Paluszkiewicz, P; Raban, M; Smolinska, K; Tomaszewska, E; Turska, M; Turski, WA; Walczak, K, 2019)
"Obesity is associated with impaired learning, but the mechanisms underlying this cognitive dysfunction are poorly understood."1.91Obesity-Induced Memory Deficits in Female Rats Are Oestrous Cycle Dependent and Linked to Impaired Brain Kynurenine Pathway Metabolism. ( Bolaños-Jiménez, F; Croyal, M; García Santillán, JA; Gourdel, M; Mezo-González, CE; Reyes-Castro, LA, 2023)
"Obesity is intimately associated with hypertension; increases in blood pressure are closely related to the magnitude of weight gain."1.36Role of excitatory amino acid input in rostral ventrolateral medulla neurons in rats with obesity-induced hypertension. ( Dewa, A; Suhaimi, FW; Yusof, AP; Yusoff, NH, 2010)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (60.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Mezo-González, CE1
García Santillán, JA1
Reyes-Castro, LA1
Gourdel, M1
Croyal, M1
Bolaños-Jiménez, F1
Milart, P1
Paluszkiewicz, P1
Dobrowolski, P1
Tomaszewska, E1
Smolinska, K1
Debinska, I1
Gawel, K1
Walczak, K1
Bednarski, J1
Turska, M1
Raban, M1
Kocki, T1
Turski, WA1
Oxenkrug, G1
Bernstein, HG1
Guest, PC1
van der Hart, M1
Roeser, J1
Summergrad, P1
Steiner, J1
Yue, JT1
Abraham, MA1
Bauer, PV1
LaPierre, MP1
Wang, P1
Duca, FA1
Filippi, BM1
Chan, O1
Lam, TK1
Suhaimi, FW1
Yusoff, NH1
Dewa, A1
Yusof, AP1
Ye, ZY1
Li, DP1
Coppola, A1
Wenner, BR1
Ilkayeva, O1
Stevens, RD1
Maggioni, M1
Slotkin, TA1
Levin, ED1
Newgard, CB1
Vinyard, E2
Joven, CB1
Swendseid, ME2
Drenick, EJ2
Numa, S1
Hashimoto, T1
Nakanishi, S1
Okazaki, T1

Other Studies

10 other studies available for kynurenic acid and Obesity

ArticleYear
Obesity-Induced Memory Deficits in Female Rats Are Oestrous Cycle Dependent and Linked to Impaired Brain Kynurenine Pathway Metabolism.
    Neuroendocrinology, 2023, Volume: 113, Issue:5

    Topics: Animals; Brain; Female; Kynurenic Acid; Kynurenine; Memory Disorders; NAD; Obesity; Rats; Tryptophan

2023
Kynurenic acid as the neglected ingredient of commercial baby formulas.
    Scientific reports, 2019, 04-15, Volume: 9, Issue:1

    Topics: Animals; Breast Feeding; Dietary Supplements; Disease Models, Animal; Female; Gastrointestinal Tract

2019
Plasma xanthurenic acid in a context of insulin resistance and obesity in schizophrenia.
    Schizophrenia research, 2019, Volume: 211

    Topics: Case-Control Studies; Humans; Insulin Resistance; Kynurenic Acid; Kynurenine; Obesity; Schizophrenia

2019
Inhibition of glycine transporter-1 in the dorsal vagal complex improves metabolic homeostasis in diabetes and obesity.
    Nature communications, 2016, 11-22, Volume: 7

    Topics: Animals; Brain; Diabetes Mellitus, Experimental; Diet, High-Fat; Energy Metabolism; Gene Expression

2016
Role of excitatory amino acid input in rostral ventrolateral medulla neurons in rats with obesity-induced hypertension.
    Acta neurologica Belgica, 2010, Volume: 110, Issue:1

    Topics: Adiposity; Analysis of Variance; Animals; Blood Pressure; Body Weight; Disease Models, Animal; Dose-

2010
Activation of the melanocortin-4 receptor causes enhanced excitation in presympathetic paraventricular neurons in obese Zucker rats.
    Regulatory peptides, 2011, Jan-17, Volume: 166, Issue:1-3

    Topics: alpha-MSH; Animals; Bicuculline; Guanosine Diphosphate; Kynurenic Acid; Male; Melanocyte-Stimulating

2011
Branched-chain amino acids alter neurobehavioral function in rats.
    American journal of physiology. Endocrinology and metabolism, 2013, Feb-15, Volume: 304, Issue:4

    Topics: Amino Acids, Branched-Chain; Animals; Anxiety; Behavior, Animal; Brain; Diet; Diet, High-Fat; Dietar

2013
Vitamin B6 nutriture studied in obese subjects during 8 weeks of starvation.
    The American journal of clinical nutrition, 1967, Volume: 20, Issue:4

    Topics: Female; Humans; Kynurenic Acid; Kynurenine; Male; Obesity; Oxalates; Pyridoxine; Starvation; Transam

1967
Regulatory mechanisms for liver acetyl coenzyme A carboxylase.
    Biochemical Society symposium, 1972, Issue:35

    Topics: Acetyl-CoA Carboxylase; Animals; Bicarbonates; Diabetes Mellitus, Experimental; Fasting; Kinetics; K

1972
Vitamin B6 requirements in starving obese males.
    The American journal of clinical nutrition, 1969, Volume: 22, Issue:1

    Topics: Fasting; Humans; Kynurenic Acid; Male; Obesity; Pyridoxine; Time Factors; Tryptophan; Vitamin B 6 De

1969