kynurenic acid has been researched along with Nervous System Diseases in 6 studies
Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.
Nervous System Diseases: Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A rodent model of neurovisceral toxic syndrome induced by the neuroexcitant amino acid, domoic acid, is described, along with the activity of a putative antidote, the nonselective excitotoxin antagonist, kynurenic acid." | 7.68 | Domoic acid-induced neurovisceral toxic syndrome: characterization of an animal model and putative antidotes. ( Bose, R; Glavin, GB; Pinsky, C, 1990) |
| "Kynurenine is a metabolite of the tryptophan-nicotine-amide-adenine-dinucleotide pathway." | 6.38 | [Kynurenine and its metabolites in nervous system diseases]. ( Schwab, F; Vécsei, L, 1992) |
| "A rodent model of neurovisceral toxic syndrome induced by the neuroexcitant amino acid, domoic acid, is described, along with the activity of a putative antidote, the nonselective excitotoxin antagonist, kynurenic acid." | 3.68 | Domoic acid-induced neurovisceral toxic syndrome: characterization of an animal model and putative antidotes. ( Bose, R; Glavin, GB; Pinsky, C, 1990) |
| "Kynurenic acid (KYNA) is an antagonist to the α-7nACh and NMDA receptors." | 2.58 | Galantamine-Memantine Combination for Cognitive Impairments Due to Electroconvulsive Therapy, Traumatic Brain Injury, and Neurologic and Psychiatric Disorders: Kynurenic Acid and Mismatch Negativity Target Engagement. ( Koola, MM, 2018) |
| "Kynurenine is a metabolite of the tryptophan-nicotine-amide-adenine-dinucleotide pathway." | 2.38 | [Kynurenine and its metabolites in nervous system diseases]. ( Schwab, F; Vécsei, L, 1992) |
| "Quinolinic acid (QUIN) is an endogenous N-methyl-D-aspartate receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction." | 1.28 | Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease. ( Crowley, JS; Davis, LE; Demitrack, MA; Der, M; Dilling, LA; Elia, J; Heyes, MP; Kruesi, MJ; Lackner, A; Saito, K, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (66.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koola, MM | 1 |
| Shaw, CA | 1 |
| Bains, JS | 1 |
| Vécsei, L | 1 |
| Schwab, F | 1 |
| Heyes, MP | 1 |
| Saito, K | 1 |
| Crowley, JS | 1 |
| Davis, LE | 1 |
| Demitrack, MA | 1 |
| Der, M | 1 |
| Dilling, LA | 1 |
| Elia, J | 1 |
| Kruesi, MJ | 1 |
| Lackner, A | 1 |
| Boegman, RJ | 1 |
| Jhamandas, K | 1 |
| Beninger, RJ | 1 |
| Glavin, GB | 1 |
| Pinsky, C | 1 |
| Bose, R | 1 |
2 reviews available for kynurenic acid and Nervous System Diseases
| Article | Year |
|---|---|
Galantamine-Memantine Combination for Cognitive Impairments Due to Electroconvulsive Therapy, Traumatic Brain Injury, and Neurologic and Psychiatric Disorders: Kynurenic Acid and Mismatch Negativity Target Engagement.
Topics: Animals; Cognitive Dysfunction; Drug Therapy, Combination; Electroconvulsive Therapy; Galantamine; H | 2018 |
[Kynurenine and its metabolites in nervous system diseases].
Topics: Humans; Kynurenic Acid; Kynurenine; Nervous System Diseases; Quinolinic Acid; Quinolinic Acids | 1992 |
4 other studies available for kynurenic acid and Nervous System Diseases
| Article | Year |
|---|---|
Synergistic versus antagonistic actions of glutamate and glutathione: the role of excitotoxicity and oxidative stress in neuronal disease.
Topics: Animals; Behavior, Animal; Cerebral Cortex; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Exc | 2002 |
Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease.
Topics: Aged; Animals; Brain Diseases; Encephalitis; Female; HIV Infections; Humans; Kynurenic Acid; Kynuren | 1992 |
Neurotoxicity of tryptophan metabolites.
Topics: Animals; Cerebral Cortex; Choline O-Acetyltransferase; Kynurenic Acid; Male; NADP; Nervous System Di | 1990 |
Domoic acid-induced neurovisceral toxic syndrome: characterization of an animal model and putative antidotes.
Topics: Animals; Antidotes; Gastrointestinal Diseases; Kainic Acid; Kynurenic Acid; Male; Mice; Nervous Syst | 1990 |