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kynurenic acid and Ischemic Attack, Transient

kynurenic acid has been researched along with Ischemic Attack, Transient in 15 studies

Kynurenic Acid: A broad-spectrum excitatory amino acid antagonist used as a research tool.
kynurenic acid : A quinolinemonocarboxylic acid that is quinoline-2-carboxylic acid substituted by a hydroxy group at C-4.

Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)

Research Excerpts

ExcerptRelevanceReference
"1."1.30Brain concentrations of kynurenic acid after a systemic neuroprotective dose in the gerbil model of global ischemia. ( Cini, M; Dho, L; Marconi, M; Molinari, A; Post, C; Rosa, B; Salvati, P; Ukmar, G, 1999)
"Kynurenic acid (300 mg/kg) was administered i."1.27The excitatory amino acid antagonist kynurenic acid administered after hypoxic-ischemia in neonatal rats offers neuroprotection. ( Andiné, P; Ellrén, K; Hagberg, H; Kjellmer, I; Lehmann, A; Nielsen, T; Wennberg, E, 1988)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's13 (86.67)18.2507
2000's1 (6.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pellegrini-Giampietro, DE1
Cozzi, A1
Moroni, F1
Ghribi, O1
Callebert, J1
Plotkine, M1
Boulu, RG2
Wood, ER2
Bussey, TJ2
Phillips, AG2
Speciale, C1
Cini, M2
Wu, HQ1
Salvati, P2
Schwarcz, R1
Molinari, A2
Calabresi, M1
Varasi, M1
Berger, R1
Jensen, A1
Hossmann, KA1
Paschen, W1
Ukmar, G1
Dho, L1
Rosa, B1
Marconi, M1
Post, C1
Allaf, R1
Vistelle, R1
Katayama, Y1
Kawamata, T1
Kano, T1
Tsubokawa, T1
McCulloch, J1
Roucher, P1
Meric, P1
Correze, JL1
Mispelter, J1
Tiffon, B1
Lhoste, JM1
Seylaz, J2
Lobner, D1
Lipton, P1
Gill, R1
Woodruff, GN1
Roussel, S1
Pinard, E1
Andiné, P1
Lehmann, A1
Ellrén, K1
Wennberg, E1
Kjellmer, I1
Nielsen, T1
Hagberg, H1

Other Studies

15 other studies available for kynurenic acid and Ischemic Attack, Transient

ArticleYear
The glycine antagonist and free radical scavenger 7-Cl-thio-kynurenate reduces CA1 ischemic damage in the gerbil.
    Neuroscience, 1994, Volume: 63, Issue:3

    Topics: Animals; Body Temperature; Female; Free Radical Scavengers; Gene Expression; Gerbillinae; Glycine; H

1994
Effect of kynurenic acid on the ischaemia-induced accumulation of glutamate in rat striatum.
    Neuroreport, 1994, Jan-12, Volume: 5, Issue:4

    Topics: Animals; Aspartic Acid; Corpus Striatum; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Aci

1994
A glycine antagonist 7-chlorokynurenic acid attenuates ischemia-induced learning deficits.
    Neuroreport, 1993, Volume: 4, Issue:2

    Topics: Analysis of Variance; Animals; Cerebral Ventricles; Discrimination, Psychological; Glycine; Hippocam

1993
Kynurenic acid-enhancing and anti-ischemic effects of the potent kynurenine 3-hydroxylase inhibitor FCE 28833 in rodents.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Animals; Brain; Butyrates; Enzyme Inhibitors; Gerbillinae; Hippocampus; Hydrolases; Ischemic Attack,

1996
No effect of glutamate on metabolic disturbances in hippocampal slices of mature fetal guinea pigs after transient in vitro ischemia.
    Brain research. Developmental brain research, 1997, Jul-18, Volume: 101, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Dizocilpine Maleate; Energy Metabolism; Excitatory Amino Acid Antag

1997
Brain concentrations of kynurenic acid after a systemic neuroprotective dose in the gerbil model of global ischemia.
    Progress in neuro-psychopharmacology & biological psychiatry, 1999, Volume: 23, Issue:4

    Topics: Animals; Body Temperature; Brain; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Kynurenic Ac

1999
[Inefficacy of N-methyl-D-aspartate receptor complex antagonists on behavioral and histologic consequences of global cerebral ischemia in rats].
    Annales pharmaceutiques francaises, 2000, Volume: 58, Issue:4

    Topics: Animals; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Ischemic Attack, Transient;

2000
A glycine antagonist reduces ischemia-induced CA1 cell loss in vivo.
    Neuroscience letters, 1992, Sep-28, Volume: 145, Issue:1

    Topics: Animals; Glycine; Hippocampus; Injections, Intraventricular; Ischemic Attack, Transient; Kynurenic A

1992
Excitatory amino acid antagonist administered via microdialysis attenuates lactate accumulation during cerebral ischemia and subsequent hippocampal damage.
    Brain research, 1992, Jul-03, Volume: 584, Issue:1-2

    Topics: Amino Acids; Animals; Dialysis; Gerbillinae; Glucose; Hippocampus; Histocytochemistry; Ischemic Atta

1992
Ischaemic brain damage--prevention with competitive and non-competitive antagonists of N-methyl-D-aspartate receptors.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:3A

    Topics: Animals; Cats; Cerebral Arteries; Dextrorphan; Dizocilpine Maleate; Hematoma, Subdural; Ischemic Att

1991
Metabolic effects of kynurenate during reversible forebrain ischemia studied by in vivo 31P-nuclear magnetic resonance spectroscopy.
    Brain research, 1991, May-31, Volume: 550, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain; Ischemic Attack, Transient; Kynurenic

1991
Sigma-ligands and non-competitive NMDA antagonists inhibit glutamate release during cerebral ischemia.
    Neuroscience letters, 1990, Sep-04, Volume: 117, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anticonvulsants; Cyclazocine; Dizocilpine Maleate

1990
The neuroprotective actions of kynurenic acid and MK-801 in gerbils are synergistic and not related to hypothermia.
    European journal of pharmacology, 1990, Feb-06, Volume: 176, Issue:2

    Topics: Animals; Body Temperature; Brain; Carotid Arteries; Dibenzocycloheptenes; Dizocilpine Maleate; Drug

1990
Kynurenate does not reduce infarct size after middle cerebral artery occlusion in spontaneously hypertensive rats.
    Brain research, 1990, Jun-04, Volume: 518, Issue:1-2

    Topics: Animals; Caudate Nucleus; Cerebral Arteries; Cerebral Cortex; Cerebral Infarction; Ischemic Attack,

1990
The excitatory amino acid antagonist kynurenic acid administered after hypoxic-ischemia in neonatal rats offers neuroprotection.
    Neuroscience letters, 1988, Jul-19, Volume: 90, Issue:1-2

    Topics: Animals; Brain; Brain Edema; Cerebrovascular Disorders; Female; Hypoxia; Ischemic Attack, Transient;

1988